Zobrazeno 1 - 10
of 24
pro vyhledávání: '"B C Langton"'
Autor:
B. C. Langton, H.-L. C. Liu, D. L. Parkes, M. Longhi, M. P. Mcgrogan, L. A. Chao, J. W. Brandis, S. S. Elliger, L. K. Shawver, Jian-Ai Xuan
Publikováno v:
Biochemical and Biophysical Research Communications. 211:792-803
We describe the chimerization of a monoclonal antibody directed against the c-erbB-2 protein using a novel PCR method for cloning immunoglobulin variable region genes. We also describe the characterization of the chimera and show its potential use fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b1712c664b9c64e77da4517e9c9c23
https://doi.org/10.1006/bbrc.1995.1882
https://doi.org/10.1006/bbrc.1995.1882
Autor:
Cecilia A, Svelander, Evelina A, Tibäck, Lilia M, Ahrné, Maud I B C, Langton, Ulf S O, Svanberg, Marie A G, Alminger
Publikováno v:
Journal of the science of food and agriculture. 90(10)
Human studies have demonstrated that processing of tomato can greatly increase lycopene bioavailability. However, the difference between processing methods is not widely investigated. In the current study different thermal treatments of tomato were e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e81d1be7314df74247bd348d71b9e72
https://pubmed.ncbi.nlm.nih.gov/20564447
https://pubmed.ncbi.nlm.nih.gov/20564447
Autor:
B C Langton-Webster, Xiao-Li You, Lily Yen, Moulay A. Alaoui-Jamali, Stéphane Richard, Z R Nie
Publikováno v:
Oncogene. 14(15)
We have examined the role of erbB-2 expression in the modulation of cellular toxicity to cisplatin. We have demonstrated that treatment of NIH3T3-erbB-2 cells, which overexpress the p185(erbB-2) product of the human erbB-2 gene, with a monoclonal ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a09aab25256fff64fc660f1e3d4696c
https://pubmed.ncbi.nlm.nih.gov/9150389
https://pubmed.ncbi.nlm.nih.gov/9150389
Publikováno v:
Molecular carcinogenesis. 15(2)
Serially transplantable rat mammary tumor (RMT) cells are not dependent on exogenous epidermal growth factor (EGF) and insulin-like growth factor-I for continuous growth in serum-free medium. Previously, we found that conditioned medium obtained from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::338c245624008894824c981c49c95932
https://pubmed.ncbi.nlm.nih.gov/8599580
https://pubmed.ncbi.nlm.nih.gov/8599580
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 5(12)
Overexpression of the c-erbB-2 protein (gp185c-erbB-2) is correlated with a tumorigenic phenotype and may contribute to disease progression. We have reported previously on an anti-gp185c-erbB-2 antibody, TAb 250, that inhibits in vitro and in vivo gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d7cda8c8fbda4677779ba6c841862e0
https://pubmed.ncbi.nlm.nih.gov/7696185
https://pubmed.ncbi.nlm.nih.gov/7696185
Autor:
Allan Lipton, R. P. Walker, B. C. Langton, Y. L. Matthews, H. Al-Mondhiry, J. R. Dasch, L. M. Witters
Publikováno v:
International Journal of Oncology.
Transforming growth factors-alpha and -beta1 are thought to play a role in carcinogenesis. Using a sandwich linked immunosorbent assay, we have measured TGF-alpha and -beta1 levels in malignant human plasma and effusions. TGF-alpha and -beta1 plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654929ddfafa1ded719278af649d9020
https://doi.org/10.3892/ijo.4.4.943
https://doi.org/10.3892/ijo.4.4.943
Publikováno v:
Cancer research. 51(17)
A monoclonal antibody (TAb 250) specific to an extracellular epitope of the c-erbB-2 protein (gp185) inhibited the in vitro proliferation of human breast tumor cell lines that overexpress c-erbB-2 in a dose-dependent manner. Treatment of cells with c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b30094a967df0a3c89eb477ff6e7b4e
https://pubmed.ncbi.nlm.nih.gov/1678683
https://pubmed.ncbi.nlm.nih.gov/1678683
Publikováno v:
Cancer research. 51(10)
An antigen, immunologically related to the external domain of the c-erbB-2 (HER-2/neu) protein, was found shed into the serum of nude mice bearing tumors that overexpress the c-erbB-2 protein (gp185). Utilizing paired combinations from a panel of mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e8e5530d63d8e9afae1d6da4db218b8
https://pubmed.ncbi.nlm.nih.gov/1673637
https://pubmed.ncbi.nlm.nih.gov/1673637
Publikováno v:
Cancer research. 50(20)
In order to examine the role of the erbB-2 oncogene in human breast cancer, gene amplification and expression were examined in multiple stages of tumor progression. Gene amplification ranging from 2-fold to 32-fold was found in 30 (29%) of 130 cases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d80e7d3eff8f1a2e874673053976bd8
https://pubmed.ncbi.nlm.nih.gov/2208136
https://pubmed.ncbi.nlm.nih.gov/2208136
Publikováno v:
The Journal of Immunology. 141:447-456
The protein Ag, tobacco mosaic virus protein, (TMVP) and its tryptic peptide number 8 (residues 93-112 of the protein) exhibit cross-reactivity on the T cell level in some strains of mice (e.g., C3H.SW, C57BL/10); these strains are termed cross-react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ed846508b3ed1c0e3d21b3e0ba24d24
https://doi.org/10.4049/jimmunol.141.2.447
https://doi.org/10.4049/jimmunol.141.2.447