Zobrazeno 1 - 10
of 69
pro vyhledávání: '"B C, Furie"'
Autor:
H. Patel, B. C. Furie, H. A. Scoble, M. C. Huberty, B. Furie, M Bond, S. Gillis, W. B. Foster, M. Switzer
Publikováno v:
Protein Science. 6:185-196
The gamma-carboxyglutamic acid (Gla) domains of the vitamin K-dependent blood coagulation proteins contain 10 highly conserved Gla residues within the first 33 residues, but factor IX is unique in possessing 2 additional Gla residues at positions 36
Autor:
Glenn R. Larsen, Sako Dianne S, M. A. Shaffer, S A Sajer, John K. Erban, R M Gibson, B C Furie, B Furie, Ahern Tim J, Denisa D. Wagner
Publikováno v:
Journal of Biological Chemistry. 267:11104-11110
P-selectin on platelets and endothelial cells and E-selectin on endothelial cells are leukocyte receptors that recognize lineage-specific carbohydrates on neutrophils and monocytes. The proposed ligands for these receptors contain the Le(x) core and
Autor:
J N, Weitzel, J A, Sadowski, B C, Furie, R, Moroose, H, Kim, M E, Mount, M J, Murphy, B, Furie
Publikováno v:
Blood. 76:2555-2559
The vitamin K metabolism of three patients with factitious purpura due to brodifacoum ingestion was studied. These patients, who presented with bleeding disorders due to deficiency of the vitamin K-dependent blood clotting proteins, were refractory t
Publikováno v:
Journal of mass spectrometry : JMS. 35(2)
Two highly modified conotoxins from the mollusc Conus textile, epsilon-TxIX and Gla(1)-TxVI, were characterized by matrix-assisted laser desorption/ionization and electrospray mass spectrometry and also by electrospray ionization tandem and triple ma
Publikováno v:
Journal of cellular physiology. 179(1)
In order to better understand granule release from platelets, we developed an alpha-toxin permeabilized platelet model to study alpha-granule secretion. Secretion of alpha-granules was analyzed by flow cytometry using P-selectin as a marker for alpha
Publikováno v:
Blood. 93(6)
Publikováno v:
The Journal of biological chemistry. 274(4)
To understand the molecular basis of granule release from platelets, we examined the role of vesicle-associated membrane protein, SNAP-23, and syntaxin 4 in alpha-granule secretion. A vesicle-associated membrane protein, SNAP-23, and syntaxin 4 were
Publikováno v:
Seminars in hematology. 34(4)
Leukocytes, platelets, and endothelial cells interact at sites of vascular injury and inflammation through adhesion receptors on the cell surface. On binding of ligand to receptor, these receptors initiate intracellular signaling that leads to the mo
Publikováno v:
Seminars in hematology. 34(4)
Some of the interactions between coagulation factors and neutrophils are described. Proteins of the contact system, FXa, thrombin, and fibrinogen all bind to various sites on the neutrophil. This binding has a dual purpose: the assembly of coagulatio
Autor:
B C, Furie, B, Furie
Publikováno v:
Thrombosis and haemostasis. 78(1)
The vitamin K-dependent gamma-glutamyl carboxylase catalyzes the conversion of glutamic acid to gamma-carboxyglutamic acid in substrate proteins. The enzyme has recently been purified and the cDNA encoding the enzyme has been cloned. The availability