Zobrazeno 1 - 10
of 34
pro vyhledávání: '"B C, Berk"'
Publikováno v:
Trends in cardiovascular medicine. 1(3)
Restenosis following successful coronary balloon angioplasty remains one of major limitations of this procedure. It is now known that intimal hyperplasia is the primary cause of restenosis. Angioplasty injury of arteries causes activation of platelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31f06bb5e47d046affdc46141656b005
https://pubmed.ncbi.nlm.nih.gov/21239324
https://pubmed.ncbi.nlm.nih.gov/21239324
Publikováno v:
Archives des maladies du coeur et des vaisseaux. 97(12)
Oxidative stress, a state of excessive reactive oxygen species (ROS) activity, has been implicated in the pathogenesis of cardiovascular disease, including atherosclerosis, hypertension, and restenosis. Recently we have identified several SOXFs (Secr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0977554afd65e96ac69dc791ef217608
https://pubmed.ncbi.nlm.nih.gov/15669369
https://pubmed.ncbi.nlm.nih.gov/15669369
Publikováno v:
Trends in cardiovascular medicine. 9(8)
Signal transduction downstream of tyrosine kinases has become an increasingly important area of study in cardiovascular biology. In this review, we consider the experimental evidence pointing to significant roles for the Axl receptor tyrosine kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aaa8604a326a4da72faf8d58ae92beef
https://pubmed.ncbi.nlm.nih.gov/11094334
https://pubmed.ncbi.nlm.nih.gov/11094334
Autor:
J, Haendeler, B C, Berk
Publikováno v:
Regulatory peptides. 95(1-3)
It has been 100 years since the discovery of renin by Bergman and Tigerstedt. Since then, numerous studies have advanced our understanding of the renin-angiotensin system. A remarkable aspect was the discovery that angiotensin II (AngII) is the centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::114daf263d70721c7a0a02b6e7fc39d9
https://pubmed.ncbi.nlm.nih.gov/11062326
https://pubmed.ncbi.nlm.nih.gov/11062326
Publikováno v:
The Journal of biological chemistry. 275(21)
Several signal transduction events induced by angiotensin II (AngII) binding to the angiotensin II type 1 receptor resemble those evoked by platelet-derived growth factor (PDGF) binding to the PDGF-beta receptor (PDGFbeta-R). We report here, in agree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed9f62a2541c8e072f25bf096b11af71
https://pubmed.ncbi.nlm.nih.gov/10748142
https://pubmed.ncbi.nlm.nih.gov/10748142
Autor:
B C, Berk
Publikováno v:
Thrombosis and haemostasis. 82(2)
Multiple enzymes may stimulate ROS production in VSMC and endothelial cells. These include NADH/NADPH oxidase, xanthine oxidase, lipoxygenases, cyclooxygenase, P-450 monooxygenases, and the enzymes of mitochondrial oxidative phosphorylation. In addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46c5325d9325d30ab8bf53875688f4c8
https://pubmed.ncbi.nlm.nih.gov/10605787
https://pubmed.ncbi.nlm.nih.gov/10605787
Publikováno v:
The Journal of biological chemistry. 274(29)
Fluid shear stress is an important regulator of endothelial cell (EC) function. To determine whether mechanosensitive ion channels participate in the EC response to shear stress, we characterized the role of ion transport in shear stress-mediated ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58b873ea7b2441bdd614caf97384dda0
https://pubmed.ncbi.nlm.nih.gov/10400628
https://pubmed.ncbi.nlm.nih.gov/10400628
Publikováno v:
The Journal of biological chemistry. 274(29)
The Na+/H+ exchanger isoform-1 (NHE-1) is the key member of a family of exchangers that regulates intracellular pH and cell volume. Activation of NHE-1 by growth factors is rapid, correlates with increased NHE-1 phosphorylation and cell alkalinizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4d9e177b1ec8038707165439d08f6c0
https://pubmed.ncbi.nlm.nih.gov/10400637
https://pubmed.ncbi.nlm.nih.gov/10400637
Autor:
B C, Berk
Publikováno v:
Journal of the American Society of Nephrology : JASN. 10
In this review, the signal events regulated by angiotensin II (AngII) in vascular smooth muscle are analyzed based on activation of specific tyrosine kinases. AngII has been shown to play a critical role in the pathogenesis of hypertension, inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e99727cf7d42fc9b04436c903c2d1a0d
https://pubmed.ncbi.nlm.nih.gov/9892142
https://pubmed.ncbi.nlm.nih.gov/9892142
Publikováno v:
The Journal of biological chemistry. 274(1)
Mitogen-activated protein (MAP) kinases including ERK1/2 and JNK play an important role in shear stress-mediated gene expression in endothelial cells (EC). A new MAP kinase termed big MAP kinase 1 (BMK1/ERK5) has been shown to phosphorylate and activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1601e8102ee1eebc42431a9a5150e2af
https://pubmed.ncbi.nlm.nih.gov/9867822
https://pubmed.ncbi.nlm.nih.gov/9867822