Zobrazeno 1 - 10
of 723
pro vyhledávání: '"B Brett, Finlay"'
Autor:
Katherine Donald, B. Brett Finlay
Publikováno v:
Frontiers in Allergy, Vol 5 (2024)
In addition to numerous clinical studies, research using experimental models have contributed extensive evidence to the link between antibiotic exposure and atopic disease. A number of mouse models of allergy have been developed and used to uncover t
Externí odkaz:
https://doaj.org/article/f02d8ecf2f6b46c783d495217746721a
Autor:
Katherine Donald, B. Brett Finlay
Publikováno v:
Frontiers in Allergy, Vol 5 (2024)
The gut houses 70%–80% of the body's immune cells and represents the main point of contact between the immune system and the outside world. Immune maturation occurs largely after birth and is guided by the gut microbiota. In addition to the many hu
Externí odkaz:
https://doaj.org/article/95ef1dcdf5ef460abf57ed3e9e172b5b
Autor:
Katherine Donald, Antonio Serapio-Palacios, Zachary Gerbec, Tahereh Bozorgmehr, Ravi Holani, Ana Raquel Cruz, Pamela Schnupf, B. Brett Finlay
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114835- (2024)
Summary: Asthma susceptibility is linked to dysbiosis in early-life gut microbiota, and the antibody secretory immunoglobulin (Ig)A (SIgA) is a key determinant of gut microbiota composition. SIgA is obtained through breast milk during the critical ea
Externí odkaz:
https://doaj.org/article/308792914f924ccfbabfef94ed518275
Autor:
Sarah E Woodward, Laurel M P Neufeld, Jorge Peña-Díaz, Wenny Feng, Antonio Serapio-Palacios, Isabel Tarrant, Wanyin Deng, B Brett Finlay
Publikováno v:
PLoS Biology, Vol 22, Iss 8, p e3002761 (2024)
Enteric pathogens navigate distinct regional microenvironments within the intestine that cue important adaptive behaviors. We investigated the response of Citrobacter rodentium, a model of human pathogenic Escherichia coli infection in mice, to regio
Externí odkaz:
https://doaj.org/article/bf39aca966254f04bdd241b67abf2f66
Autor:
Isabel Tarrant, B. Brett Finlay
Publikováno v:
Frontiers in Microbiomes, Vol 3 (2024)
With the global prevalence of allergic disease continuing to rise at an alarming rate, the need for effective and safe therapeutics is paramount. Given the critical role of the early-life microbiota on immune development, emerging research suggests t
Externí odkaz:
https://doaj.org/article/39aa3fc314fa40b49251cf633d089d41
Autor:
Courtney Hoskinson, Darlene L. Y. Dai, Kate L. Del Bel, Allan B. Becker, Theo J. Moraes, Piushkumar J. Mandhane, B. Brett Finlay, Elinor Simons, Anita L. Kozyrskyj, Meghan B. Azad, Padmaja Subbarao, Charisse Petersen, Stuart E. Turvey
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Allergic diseases affect millions of people worldwide. An increase in their prevalence has been associated with alterations in the gut microbiome, i.e., the microorganisms and their genes within the gastrointestinal tract. Maturation of the
Externí odkaz:
https://doaj.org/article/03daefb63c6e493985002af451b630a4
Autor:
Carolina Tropini, B. Brett Finlay, Mark Nichter, Melissa K. Melby, Jessica L. Metcalf, Maria Gloria Dominguez-Bello, Liping Zhao, Margaret J. McFall-Ngai, Naama Geva-Zatorsky, Katherine R. Amato, Eduardo A. Undurraga, Hendrik N. Poinar, Jack A. Gilbert
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTThere is concern that the time taken to publish academic papers in microbiological science has significantly increased in recent years. While the data do not specifically support this, evidence suggests that editors are having to invite more
Externí odkaz:
https://doaj.org/article/6875683cea994700b14c0a85ec5a39a1
Autor:
Jorge Peña-Díaz, Sarah E. Woodward, Anna Creus-Cuadros, Antonio Serapio-Palacios, Stephanie Ortiz-Jiménez, Wanyin Deng, B. Brett Finlay
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTQuorum Sensing (QS) is a form of cell-to-cell communication that enables bacteria to modify behavior according to their population density. While QS has been proposed as a potential intervention against pathogen infection, QS-mediated communi
Externí odkaz:
https://doaj.org/article/3caac1b9dd6149da95e55fd585e5bb07
Autor:
Stefanie L. Vogt, Antonio Serapio-Palacios, Sarah E. Woodward, Andrew S. Santos, Stefan P.W. de Vries, Michelle C. Daigneault, Lisa V. Brandmeier, Andrew J. Grant, Duncan J. Maskell, Emma Allen-Vercoe, B. Brett Finlay
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTEnterohemorrhagic Escherichia coli (EHEC) is a major cause of severe bloody diarrhea, with potentially lethal complications, such as hemolytic uremic syndrome. In humans, EHEC colonizes the colon, which is also home to a diverse community of
Externí odkaz:
https://doaj.org/article/a5f7afa6035e4f5d813c2f4dd3f81e59
Autor:
Paula T. Littlejohn, Haggai Bar-Yoseph, Karlie Edwards, Hong Li, Cynthia Y. Ramirez-Contreras, Ravi Holani, Avril Metcalfe-Roach, Yiyun M. Fan, Tom Min-Shih Yang, Nina Radisavljevic, Xiaoke Hu, James D. Johnson, B. Brett Finlay
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
IntroductionMicronutrients perform a wide range of physiological functions essential for growth and development. However, most people still need to meet the estimated average requirement worldwide. Globally, 2 billion people suffer from micronutrient
Externí odkaz:
https://doaj.org/article/b4ffca3968ed454d99e7b9e36376f9cd