Zobrazeno 1 - 10
of 34
pro vyhledávání: '"B Brennhausen"'
Publikováno v:
Journal of Lipid Research, Vol 28, Iss 1, Pp 87-99 (1986)
Cholesterol efflux was studied from cholesteryl esterladen mouse peritoneal macrophages in the presence of Tangier lipoproteins derived from fasting and postprandial sera of three patients homozygous for Tangier disease (analphalipoproteinemia). The
Externí odkaz:
https://doaj.org/article/ef78631a32b5438b97dc1adbdb58c385
Autor:
Susanne Mohr, Andrea Cignarella, Paul Cullen, A. von Eckardstein, B Brennhausen, Gerd Assmann
Publikováno v:
Scopus-Elsevier
In this study, we investigated the impact of the common apoE polymorphism on apoE metabolism and cholesterol homeostasis in monocyte-derived macrophages isolated from E2/2, E3/3, and E4/4 subjects. Unloaded cells of all genotypes contained similar am
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 17:1591-1598
Abstract Identification of genes expressed during foam cell formation is important for understanding the molecular basis of atherosclerosis. We used polymerase chain reaction (PCR)–based differential display to isolate differentially expressed cDNA
Publikováno v:
Scopus-Elsevier
Abstract —Lovastatin has been shown to reduce cholesterol esterification in cholesterol-loaded human macrophages. Surprisingly, in nonloaded macrophages, lovastatin produces the opposite effect, lowering free cholesterol and increasing cholesteryl
Publikováno v:
Arzneimittel-Forschung. 40(3A)
The antiatherogenic effects of Ca2(+)-antagonists have been proved in animal studies and in man. It is suggested that drugs of this class--unlike lipid-lowering drugs--do not exert their effects by decreasing lipoprotein plasma levels but by a modula
Autor:
Arnold von Eckardstein, Gerd Assmann, Susanne Mohr, Paul Cullen, Andrea Cignarella, B Brennhausen
Publikováno v:
Atherosclerosis. 134:229
Publikováno v:
Journal of Lipid Research, Vol 26, Iss 3, Pp 316-326 (1985)
Triglyceride-rich lipoproteins derived from ten normo- and hyperlipidemic apoE-2 homozygotes were analyzed for their composition, beta-VLDL content, and their ability to induce cholesteryl ester storage in macrophages. In six of these probands apoE s
Publikováno v:
Journal of Lipid Research, Vol 28, Iss 1, Pp 87-99 (1986)
Cholesterol efflux was studied from cholesteryl esterladen mouse peritoneal macrophages in the presence of Tangier lipoproteins derived from fasting and postprandial sera of three patients homozygous for Tangier disease (analphalipoproteinemia). The
Publikováno v:
The EMBO Journal. 4:2773-2779
The interaction of human serum high density lipoproteins (HDL) with mouse peritoneal macrophages and human blood monocytes was studied. Saturation curves for binding of apolipoprotein E-free [125I]HDL3 showed at least two components: non-specific bin