Zobrazeno 1 - 10
of 26
pro vyhledávání: '"B Bishal Paudel"'
Autor:
Andrew J Sweatt, Cameron D Griffiths, Sarah M Groves, B Bishal Paudel, Lixin Wang, David F Kashatus, Kevin A Janes
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 11, Pp 1230-1256 (2024)
Abstract Protein copy numbers constrain systems-level properties of regulatory networks, but proportional proteomic data remain scarce compared to RNA-seq. We related mRNA to protein statistically using best-available data from quantitative proteomic
Externí odkaz:
https://doaj.org/article/a78905cf20e7454b93c42dc6ce895a86
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Activation of HER2/ErbB2 coincides with escape from ductal carcinoma in situ (DCIS) premalignancy and disrupts 3D organization of cultured breast-epithelial spheroids. The 3D phenotype is infrequent, however, and mechanisms for its incomplet
Externí odkaz:
https://doaj.org/article/e4f6632f41424200a4e45040e9ff3b15
Autor:
Dongya Jia, B. Bishal Paudel, Corey E. Hayford, Keisha N. Hardeman, Herbert Levine, José N. Onuchic, Vito Quaranta
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Cancer cells adjust their metabolic profiles to evade treatment. Metabolic adaptation is complex and hence better understood by an integrated theoretical-experimental approach. Using a minimal kinetic model, we predicted a previously undescribed Low/
Externí odkaz:
https://doaj.org/article/66e1a2f71e334430b77cb4dff30e193a
Autor:
B. Bishal Paudel, Su-Fern Tan, Todd E. Fox, Johnson Ung, Jeremy Shaw, Wendy Dunton, Irene Lee, Arati Sharma, Aaron D. Viny, Brian M. Barth, Martin S. Tallman, Myles Cabot, Francine E. Garrett-Bakelman, Ross L. Levine, Mark Kester, David Claxton, David J. Feith, Kevin A. Janes, Thomas P. Loughran
Publikováno v:
bioRxiv
Acute myeloid leukemia (AML) is an aggressive disease with complex and heterogeneous biology. Although several genomic classifications have been proposed, there is a growing interest in going beyond genomics to stratify AML. In this study, we profile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d818fb462fe8955009591cb49d720dd6
https://europepmc.org/articles/PMC10153188/
https://europepmc.org/articles/PMC10153188/
Autor:
Vito Quaranta, Melissa L. Kemp, John A. McLean, Stacy D. Sherrod, Simona G. Codreanu, Philip E. Stauffer, Charles J. Robbins, Corey E. Hayford, Keisha N. Hardeman, Joshua E. Lewis, B. Bishal Paudel
Table S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad27b34e0276dff01c148e6f016682ff
https://doi.org/10.1158/0008-5472.22424584
https://doi.org/10.1158/0008-5472.22424584
Autor:
Vito Quaranta, Melissa L. Kemp, John A. McLean, Stacy D. Sherrod, Simona G. Codreanu, Philip E. Stauffer, Charles J. Robbins, Corey E. Hayford, Keisha N. Hardeman, Joshua E. Lewis, B. Bishal Paudel
Supplementary Information, Methods, Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa0d19b58d024690744656262a7aca3
https://doi.org/10.1158/0008-5472.22424590.v1
https://doi.org/10.1158/0008-5472.22424590.v1
Autor:
Vito Quaranta, Melissa L. Kemp, John A. McLean, Stacy D. Sherrod, Simona G. Codreanu, Philip E. Stauffer, Charles J. Robbins, Corey E. Hayford, Keisha N. Hardeman, Joshua E. Lewis, B. Bishal Paudel
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e250d2be22597b837d948a1366ec0a08
https://doi.org/10.1158/0008-5472.22424593
https://doi.org/10.1158/0008-5472.22424593
Autor:
Vito Quaranta, Melissa L. Kemp, John A. McLean, Stacy D. Sherrod, Simona G. Codreanu, Philip E. Stauffer, Charles J. Robbins, Corey E. Hayford, Keisha N. Hardeman, Joshua E. Lewis, B. Bishal Paudel
Melanomas harboring BRAF mutations can be treated with BRAF inhibitors (BRAFi), but responses are varied and tumor recurrence is inevitable. Here we used an integrative approach of experimentation and mathematical flux balance analyses in BRAF-mutate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fa4f055b408dddf892a2c14c461bdf7
https://doi.org/10.1158/0008-5472.c.6511816.v1
https://doi.org/10.1158/0008-5472.c.6511816.v1
Autor:
Charles J. Robbins, Stacy D. Sherrod, Vito Quaranta, Joshua E. Lewis, B. Bishal Paudel, Simona G. Codreanu, Keisha N. Hardeman, Melissa L. Kemp, Corey E. Hayford, John A. McLean, Philip E. Stauffer
Publikováno v:
Cancer Res
Melanomas harboring BRAF mutations can be treated with BRAF inhibitors (BRAFi), but responses are varied and tumor recurrence is inevitable. Here we used an integrative approach of experimentation and mathematical flux balance analyses in BRAF-mutate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d12be9ea77745ea645ffd99ec951534
https://doi.org/10.1158/0008-5472.can-19-3588
https://doi.org/10.1158/0008-5472.can-19-3588
Autor:
Corey E. Hayford, Philip E. Stauffer, Blake Baleami, B. Bishal Paudel, Darren R. Tyson, Aziz Al’Khafaji, Kaitlyn E. Johnson, Leonard A. Harris, Amy Brock, Vito Quaranta
There is increasing interest in cancer cell subpopulations that can withstanding treatment via non-genetic mechanisms, such as tumor cell plasticity and adaptation. These cell populations may be comprised of cells with diverse phenotypes, e.g., quies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac3c6f55fe925e1d06e5c4ac07b9b741
https://doi.org/10.1101/2022.02.03.479045
https://doi.org/10.1101/2022.02.03.479045