Zobrazeno 1 - 10
of 181
pro vyhledávání: '"B B Yao"'
Publikováno v:
African Journal of Nephrology, Vol 3, Iss 2, Pp 84-87 (1999)
The authors studied the clinical features of high hypertension (blood pressure over 240 mmHg for the systolic and over 140 mmHg for the diastolic pressure) in 300 black African patients observed in the unit of medical emergency at Abidjan. In this un
Externí odkaz:
https://doaj.org/article/5aa77265c34d483ab1b76271893a2df5
Publikováno v:
Journal of human hypertension. 32(1)
Hypertension is the most significant modifiable risk factor for cerebrovascular disease. It has been estimated that about 54% of strokes worldwide can be attributed to hypertension. However, there has not been a systematic study assessing the shared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a822c8edb5948cc43162d9f9b3adab80
https://pubmed.ncbi.nlm.nih.gov/29176593
https://pubmed.ncbi.nlm.nih.gov/29176593
Publikováno v:
Journal of human hypertension. 31(11)
In candidate gene era, dozens of single-nucleotide polymorphisms (SNPs) within renin-angiotensin-aldosterone system (RAAS) have been reported to be significantly associated with hypertension. However, the unbiased genome-wide association studies (GWA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81206aa929a6b9426ff1bb91f75a01eb
https://pubmed.ncbi.nlm.nih.gov/28425437
https://pubmed.ncbi.nlm.nih.gov/28425437
Akademický článek
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Autor:
B B Yao, William A. Carroll, Jennifer M. Frost, Madhavi Pai, George K. Grayson, Chang Zhu, Bradley A. Hooker, Alan S. Florjancic, Karin R. Tietje, Michael Meyer, Anthony V. Daza, Michael J. Dart, Tiffany Runyan Garrison, Derek W. Nelson, Keith B. Ryther, Gin C. Hsieh, Prasant Chandran, Odile F. El-Kouhen, Yihong Fan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:2604-2608
SAR studies on a series of thiophene amide derivatives provided CB(2) receptor agonists. The activity of the compounds was characterized by radioligand binding determination, multiple functional assays, ADME, and pharmacokinetic studies. A representa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82cec3e6fc78e745dc4ab01db88eb9d1
https://doi.org/10.1016/j.bmcl.2012.01.121
https://doi.org/10.1016/j.bmcl.2012.01.121
Autor:
Michael J. Dart, Cenchen Zhan, Anita K. Salyers, Erica J. Wensink, Gin C. Hsieh, Chang Z. Zhu, Michael Meyer, Prisca Honore, Madhavi Pai, B B Yao, Prasant Chandran, Bradley A. Hooker, William A. Carroll
Publikováno v:
British Journal of Pharmacology. 162:428-440
BACKGROUND AND PURPOSE Cannabinoid CB2 receptor activation by selective agonists has been shown to produce analgesic effects in preclinical models of inflammatory and neuropathic pain. However, mechanisms underlying CB2-mediated analgesic effects rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aec659da5cbbff4819a96b971300a12
https://doi.org/10.1111/j.1476-5381.2010.01046.x
https://doi.org/10.1111/j.1476-5381.2010.01046.x
Akademický článek
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Autor:
Prisca Honore, Chang Z. Zhu, Joseph P. Mikusa, PR Hollingsworth, B B Yao, Michael J. Dart, Prasant Chandran, Y Fan, Madhavi Pai, Meyer, Anthony V. Daza, Michael W. Decker, Gin C. Hsieh
Publikováno v:
British Journal of Pharmacology. 157:645-655
Background and purpose: Activation of cannabinoid (CB) receptors decreases nociceptive transmission in inflammatory or neuropathic pain states. However, the effects of CB receptor agonists in post-operative pain remain to be investigated. Here, we ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15c8faeb58b8934eefb4d87235c8422a
https://doi.org/10.1111/j.1476-5381.2009.00184.x
https://doi.org/10.1111/j.1476-5381.2009.00184.x
Publikováno v:
Neuroscience. 158:1652-1661
We investigated the systemic and site-specific actions of a selective CB 2 receptor agonist, A-836339 on mechanically evoked (10 g von Frey hair) and spontaneous firing of spinal wide dynamic range (WDR) neurons in neuropathic (L5 and L6 ligations) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19973308a4ef066472f3b0177d7430a
https://doi.org/10.1016/j.neuroscience.2008.11.015
https://doi.org/10.1016/j.neuroscience.2008.11.015
Autor:
Anthony V. Daza, Odile F. El-Kouhen, B B Yao, Prasant Chandran, Lanlan Li, Madhavi Pai, Gin C. Hsieh, Karin R. Tietje, Michael Meyer, Michael J. Dart, Chang Z. Zhu, George K. Grayson, Tiffany Runyan Garrison, Loan N. Miller, Jennifer M. Frost
Publikováno v:
Journal of Medicinal Chemistry. 51:1904-1912
A series of potent indol-3-yl-tetramethylcyclopropyl ketones have been prepared as CB 2 cannabinoid receptor ligands. Two unsubstituted indoles ( 5, 32) were the starting points for an investigation of the effect of indole ring substitutions on CB 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13c95b673144663e4abfb3fb3c6db76
https://doi.org/10.1021/jm7011613
https://doi.org/10.1021/jm7011613