Zobrazeno 1 - 10
of 681
pro vyhledávání: '"B B, Cohen"'
Autor:
Colin A. Purdie, Michael Steel, Anne L. Robertson, HJ Stewart, J Paxton, M McCallum, B B Cohen, C Baker, David Cameron, R E Leake, R. C. F. Leonard, A Gould, K Gillespie
Publikováno v:
British Journal of Cancer
There is long-standing controversy over the management of small, node-negative breast cancers. Surgical excision, with or without local radiotherapy, plus adjuvant tamoxifen will result in long-term disease-free survival for some 80% of patients. On
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685b4461f822c0e296c42652b351fd18
https://doi.org/10.1038/sj.bjc.6601826
https://doi.org/10.1038/sj.bjc.6601826
Autor:
B. B. Cohen, D. M. Eccles, A. Lessels, L. Taylor, C. M. Steel, John F. Smyth, Hani Gabra, R. C. F. Leonard
Publikováno v:
British Journal of Cancer
Allele imbalance on chromosome 11 loci in ovarian cancer is a frequent event, suggesting the presence of tumour-suppressor genes for ovarian carcinogenesis on this chromosome. Ten highly polymorphic (CA) repeat microsatellites were used to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e98604f31b2da92c30e6f019eda33a
https://doi.org/10.1038/bjc.1995.340
https://doi.org/10.1038/bjc.1995.340
Publikováno v:
International Journal of Cancer. 53:188-198
Fifteen pedigrees with a total of 75 cases of breast cancer, 10 of ovarian cancer and 53 of other cancers have been collected. Polymorphic markers on chromosome 17q have been screened to locate a putative breast-cancer gene using DNA from relevant in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f74ac79dc7a6419b9efb634f547458
https://doi.org/10.1002/ijc.2910530203
https://doi.org/10.1002/ijc.2910530203
Autor:
B B Cohen, I E Young, V A Anderson, M L Hooper, C Annink, Kathreena M Kurian, Ian Kunkler, C. M. Steel, Andrew H. Wyllie
Publikováno v:
British Journal of Cancer
The CYP17 gene codes for the cytochrome P450c17α enzyme that is involved in the synthesis of oestrogens. This case-control study from the South East of Scotland shows that a polymorphism of the CYP17 gene is associated with an increased risk of male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea9a043f271db0ea5471cc858e3fb7e
http://europepmc.org/articles/PMC2374358
http://europepmc.org/articles/PMC2374358
Autor:
Barbara L. Weber, D. M. Black, V A Anderson, Ellen Warner, E. Hoodfar, Steven A. Narod, Olufunmilayo I. Olopade, B B Cohen, R. De Mey, Rosemarie Davidson, A. Renwick, M. Micek, A. Liede, Jamie L. Dann, A. Fordyce, Mary Claire King, C. M. Steel
Publikováno v:
British Journal of Cancer
BRCA1 mutations have been identified in breast and ovarian cancer families from diverse ethnic backgrounds. We studied 17 different families with the BRCA1 2800delAA mutation; seven were ascertained in Scotland (Dundee, Edinburgh, Glasgow, St Andrews
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54111762d690f821bb719f7470a10fa1
https://pubmed.ncbi.nlm.nih.gov/10682686
https://pubmed.ncbi.nlm.nih.gov/10682686
Autor:
P, Devilee, J, Hermans, J, Eyfjörd, A L, Bøorresen, R, Lidereau, H, Sobol, A, Borg, A M, Cleton-Jansen, E, Oláh, B B, Cohen, S, Scherneck, U, Hamann, B, Peterlin, M, Caligo, Y J, Bignon, C, Maugard
Publikováno v:
Genes, chromosomescancer. 18(3)
Loss of heterozygosity (LOH) at 7q31 has been claimed to occur in over 80% of all breast cancers and to be of prognostic significance. This would make this genetic alteration the most common event observed in breast cancer to date. Others, however, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d06951cb98f14fc955bef617f5b96b1c
https://pubmed.ncbi.nlm.nih.gov/9071572
https://pubmed.ncbi.nlm.nih.gov/9071572
Publikováno v:
Public health reports (Washington, D.C. : 1974). 110(3)
Massachusetts has developed the first State profile of the causes and costs of injury based on the national study, "Cost of Injury in the United States: A Report to Congress." Incidence of fatal injuries is based on Massachusetts data; nonfatal hospi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::487cb9d4894b40f986dc89e2811f5572
https://pubmed.ncbi.nlm.nih.gov/7610211
https://pubmed.ncbi.nlm.nih.gov/7610211
Autor:
J. M. Morsman, B. B. Cohen, D. M. Eccles, H. Gabra, R. C. F. Leonard, A. Lessels, C. M. Steel, Margaret R. Wallace, L. Gruber
Publikováno v:
Ovarian Cancer 3 ISBN: 9781475701388
Analysis of tumours for localized loss of heterozygosity (LOH) or ‘allele imbalance’ is a well-recognized approach to the detection and mapping of tumour suppressor genes [1]. Studies in ovarian cancer have identified regional LOH on chromosomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc1afb5e8cf4279e3ce40c1c831ad7ca
https://doi.org/10.1007/978-1-4757-0136-4_5
https://doi.org/10.1007/978-1-4757-0136-4_5
Autor:
Udi Chetty, J.M. Dixon, C M Steel, Margaret R. Wallace, D E Porter, E Smyth, David Carter, B B Cohen
Publikováno v:
The British journal of surgery. 81(10)
Eight breast cancer pedigrees with a high probability of containing individuals with the BRCA1 gene mutation (odds 79·2–99·9 per cent) were identified through genetic linkage analysis using probes located within q12–22 on the long arm of chromo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378791cf2bf2a1570c498991f1481cdb
https://pubmed.ncbi.nlm.nih.gov/7820489
https://pubmed.ncbi.nlm.nih.gov/7820489
Publikováno v:
The British journal of surgery. 80(11)
Up to 20 per cent of cases of breast cancer diagnosed in women under the age of 45 years may be caused by an autosomal dominant gene. A present difficulty is differentiation of mutation carriers from nonmutation carriers in high-risk families. Geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284bd5e1502bd9ee504de520a36c603b
https://pubmed.ncbi.nlm.nih.gov/8252342
https://pubmed.ncbi.nlm.nih.gov/8252342