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Autor:
Abdullah Mashhour, Ahmed Alaskar, B A Somaie, Y Alobaida, S Alkhaldi, Imadul Islam, H A Alhadrami, Nimer Mehyar, A M Tolah, M Al Ghobain, Bandar Alghanem, Mohamed Boudjelal
Publikováno v:
SAR and QSAR in Environmental Research. 32:963-983
The coronavirus helicase is an essential enzyme required for viral replication/transcription pathways. Structural studies revealed a sulphate moiety that interacts with key residues within the nucleotide-binding site of the helicase. Compounds with a