Zobrazeno 1 - 10
of 44
pro vyhledávání: '"B A Jakschik"'
Publikováno v:
The Journal of Immunology. 152:1907-1914
Most studies of mast cells have been directed at their role in the pathophysiology of IgE-mediated allergic reactions with little recognition of their participation in bacterial infections. We report that mast cells can specifically bind FimH, a mann
Publikováno v:
The Journal of Immunology. 152:1380-1384
Previous investigations in our laboratory have shown that mast cells play a significant role in the initiation of immune complex-mediated inflammation. Histamine, leukotrienes, and TNF released from mast cells are important mediators of early inflamm
Publikováno v:
The Journal of Immunology. 149:2482-2487
Immunologic basement membrane injury occurs in certain human diseases. We investigated the role of mast cells in the initiation of inflammation induced by selective deposition of antibody on the basement membrane in the skin. Intradermal injection of
Publikováno v:
The Journal of Immunology. 147:1636-1641
Mast cells are secretory cells strategically located in the vicinity of blood vessels where they can readily initiate and modulate various inflammatory processes, including plasma exudation and leukocyte infiltration. We have previously shown that 50
The importance of mast cells for the neutrophil influx in immune complex-induced peritonitis in mice
Publikováno v:
The Journal of Immunology. 145:1868-1873
The role of mast cells in polymorphonuclear leukocyte (PMN) influx in Ag-antibody complex-induced peritonitis was evaluated in mast cell-deficient WBB6F1-W/Wv (W/Wv) mice and their normal littermates, WBB6F1-+/+ (+/+). Peritoneal cell influx was eval
Autor:
R, Malaviya, B A, Jakschik
Publikováno v:
The Journal of biological chemistry. 268(7)
The 5-lipoxygenase catalyzes the first two steps in the metabolism of arachidonic acid to leukotrienes. It has been shown that the calcium influx into leukocytes following stimulation by A23187 activates the enzyme and causes its translocation to the
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 262(2)
Plasma exudation characterizes the early phase of acute inflammation. The possible role of mast cells and their mediators in this event in immune complex-induced injury was studied. Dye exudation was assessed from 5 min to 2 hr after initiating rever
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 5(3)
Mast cell-endothelial cell interactions have long been suspected to be important in inflammation. The detail of the pathways of communication have yet to be elucidated. In this report we describe, for the first time, mast cell granules within endothe
Publikováno v:
Eicosanoids. 5(1)
Stimulation of peritoneal cells from BALB/c, CBA/J or WBB6F1(-)+/+ mice with IgE/antigen caused the release of mast cell granules and leukotriene C4. No leukotriene formation was observed with peritoneal cells from mast cell-deficient WBB6F1-W/Wv mic
Publikováno v:
Advances in prostaglandin, thromboxane, and leukotriene research.