Výsledky vyhledávání - "B A Brunkhorst"

Role of the Fc gamma R subclasses Fc gamma RII and Fc gamma RIII in the activation of human neutrophils by low and high valency immune complexes

Autor: G R, Strohmeier, B A, Brunkhorst, K F, Seetoo, T, Meshulam, J, Bernardo, E R, Simons

Publikováno v: Journal of leukocyte biology. 58(4)

Two Fc gamma receptor (Fc gamma R) subclasses on human neutrophils, Fc gamma RII and Fc gamma RIII, activate different cellular functions. To examine the involvement of each receptor subtype in polymorphonuclear leukocyte activation, Fab and F(ab')2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::686267ff082812b52f69e9d0d0ba26a9
https://pubmed.ncbi.nlm.nih.gov/7561517

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Differential roles of Fc gamma RII and Fc gamma RIII in immune complex stimulation of human neutrophils

Autor: B A, Brunkhorst, G, Strohmeier, K, Lazzari, G, Weil, D, Melnick, H B, Fleit, E R, Simons

Publikováno v: The Journal of biological chemistry. 267(29)

Insoluble immune complexes (IIC) stimulate human neutrophils through Fc gamma receptors. Freshly isolated human neutrophils express two FcR subclasses, FcRII and FcRIII. We explored the role of FcRII and FcRIII in this activation process by selective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2094aad0201edd32af3a2c7dd5185f1f
https://pubmed.ncbi.nlm.nih.gov/1328206

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Calcium changes in immune complex-stimulated human neutrophils. Simultaneous measurement of receptor occupancy and activation reveals full population stimulus binding but subpopulation activation

Autor: B A, Brunkhorst, K G, Lazzari, G, Strohmeier, G, Weil, E R, Simons

Publikováno v: The Journal of biological chemistry. 266(20)

Immune complexes (ICs) induce an initial transient increase in cytosolic intracellular calcium [( Ca2+]in) levels in human neutrophils (PMN). Changes in PMN [Ca2+]in were measured with the fluorescent calcium indicator Indo-1 ( [1-[2-amino-5-(6-carbo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::79924333bff8d671ec79154bf29cafe7
https://pubmed.ncbi.nlm.nih.gov/2071590

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Ammonium decreases human polymorphonuclear leukocyte cytoskeletal actin

Autor: Richard Niederman, B A Brunkhorst

Publikováno v: New York University Scholars

Ammonium, a weak base produced as a metabolic by-product of urea metabolism by bacterial pathogens, inhibits a variety of motile polymorphonuclear leukocyte (PMN) functions. It was initially assumed that the mechanism of leukocyte inhibition was due

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1fb219da49c9ddbdd4114e43e36f4b3
https://nyu.pure.elsevier.com/en/publications/4baac97d-e087-45f3-92c5-bff0290436a5

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Propionate induces polymorphonuclear leukocyte activation and inhibits formylmethionyl-leucyl-phenylalanine-stimulated activation

Autor: E Kraus, B A Brunkhorst, Maddalena V. Coppi, Richard Niederman, M Budnick

Publikováno v: New York University Scholars

Short-chain carboxylic acids (SCCA) are metabolic by-products of bacterial pathogens which can alter cytoplasmic pH and inhibit a variety of polymorphonuclear leukocyte (PMN) motile functions. Since cytoskeletal F-actin alterations are central to PMN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e30ca026f5268321b28464ed94e040
https://nyu.pure.elsevier.com/en/publications/2c222431-2c75-492e-b6dd-e2b520afc13e

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