Zobrazeno 1 - 10
of 20
pro vyhledávání: '"B A, Molitoris"'
Publikováno v:
American Journal of Physiology-Renal Physiology. 264:F907-F916
Preceding ischemia or concurrent hypotension is known to enhance aminoglycoside nephrotoxicity; however, the underlying mechanisms responsible have not been determined. To investigate the effect of preceding mild ischemia on cellular gentamicin handl
Autor:
V. Colombaro, A.-E. Decleves, V. Voisin, L. Giordano, I. Jadot, I. Habsch, B. Flamion, N. Caron, J. P. Ngo, M. Kett, J. Pearson, D. Smith, A. Abdelkader, S. Kar, J. Bertram, B. Gardiner, R. Evans, T. W. Emans, C. P. Ow, J. A. Joles, R. G. Evans, S. C. Malpas, M. P. Koeners, G. R. Dube, S. B. Campos-Bilderback, R. M. Sandoval, D. Bosukonda, P. Keck, R. Leger, P. Bey, W. Carlson, B. A. Molitoris, V. Cernaro, A. Sfacteria, S. Lucisano, R. Lupica, A. M. Bruzzese, C. Aloisi, F. Montuori, G. Lorenzano, L. Visconti, M. Buemi
Publikováno v:
Nephrology Dialysis Transplantation. 29:iii56-iii57
Publikováno v:
The International journal of artificial organs. 30(5)
Acute Kidney Injury (AKI) is a complex disorder for which currently there is no accepted definition. We describe an initiative to develop uniform standards for defining and classifying AKI and establish a forum for multidisciplinary interaction to im
Autor:
K J, Kelly, B A, Molitoris
Publikováno v:
Seminars in nephrology. 20(1)
Acute renal failure (ARF) occurs frequently and results in an unacceptably high morbidity and mortality. There is no currently accepted specific therapy that alters the course of ischemic ARF. Recent experimental advances and continued funding of ARF
Autor:
B A, Molitoris, J, Marrs
Publikováno v:
The American journal of medicine. 106(5)
Autor:
T A, Sutton, B A, Molitoris
Publikováno v:
Seminars in nephrology. 18(5)
Significant advances have been made in understanding the pathophysiology of injury at the cellular level in ischemic acute renal failure. Alterations in the actin cytoskeleton are of central importance to the structural, physiological, and biochemica
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 274(1)
An LLC-PK1 cell culture model was used to evaluate for a direct protective effect of the pentoxifylline analogue HWA-448 in gentamicin nephrotoxicity at the cellular level. Cells exposed to 2 mM gentamicin for 6 days displayed a significant decrease
Autor:
B. A. Molitoris, E. M. Fish
Publikováno v:
The American journal of physiology. 267(4 Pt 2)
Extracellular acidosis has been shown to be protective during ischemia in renal tubule cells. However, the mechanism of protection remains unknown. Since ischemia leads to disruption and polymerization of the cortical actin cytoskeleton, we hypothesi
Autor:
B A, Molitoris
Publikováno v:
Kidney international. Supplement. 36
Autor:
B. A. Molitoris
Publikováno v:
The American journal of physiology. 260(6 Pt 2)
Proximal tubule cells play a major role in the reabsorption of ions, water, and solutes from the glomerular filtrate. This is accomplished, in large part, by a surface membrane polarized into structurally, biochemically, and physiologically distinct