Zobrazeno 1 - 10
of 29
pro vyhledávání: '"B A, Konkle"'
Autor:
Margaret V. Ragni, Lynn M. Malec, Nicoletta Machin, Anne T. Neff, Peter A. Kouides, Andra H. James, B. A. Konkle, Donald Brambilla, Craig M. Kessler, Claire S. Philipp
Publikováno v:
Haemophilia. 22:397-402
Background von Willebrand disease (VWD) is the most common congenital bleeding disorder. In women, menorrhagia is the most common bleeding symptom, and is disabling with iron deficiency anaemia, high health cost and poor quality of life. Current horm
Autor:
E. Stang, J. Maahs, Joan Cox Gill, Althea M. Grant, Roshni Kulkarni, Andra H. James, Vanessa R. Byams, Peter A. Kouides, Danielle Nance, B. A. Konkle, S. McALISTER, Diane J. Nugent, Claire S. Philipp, M. M. Dumas, Deborah L. Brown, Judith Baker, J. M. Soucie
Publikováno v:
Haemophilia. 17:6-13
Inherited bleeding disorders are especially problematic for affected girls and women due to the monthly occurrence of menstrual periods and the effects on reproductive health. Although heavy menstrual bleeding (HMB) is the most common manifestation,
Autor:
R. Watts, J. E. Palascak, W. Hanna, Joan Cox Gill, J. Hord, Peter A. Kouides, Peter W. Marks, Keith Hoots, Michael D. Tarantino, B. A. Konkle, R. Shopnick, E. Kurczynski, Craig M. Kessler, Steven W. Pipe, Gilbert C. White, Alan R. Cohen, Georges-Etienne Rivard, Anne L. Angiolillo, Nigel S. Key, Donna DiMichele, Thomas C. Abshire, Leonard A. Valentino, Lisa N. Boggio, Rekha Parameswaran, Amy D. Shapiro, M. V. Ragni
Publikováno v:
Haemophilia. 11:100-106
Recombinant activated factor VII (rFVIIa), licensed in 1999 for treatment of haemophilia patients with inhibitors (HI), represents an important advance in the therapeutic armamentarium. Standard bolus dosing ranges from 90 to 120 mcg kg(-1) every 2-3
Autor:
B. A. Konkle, K. Kriz, T. Albert, K. Chu, Johannes Oldenburg, A von Felten, F. E. Maly, Bernhard Lämmle, Peter J. Baker, Walter A. Wuillemin, A. Siegemund, David Keeling
Publikováno v:
Thrombosis and Haemostasis. 85:454-457
SummaryThe recent discovery of five patients with coumarin sensitive FIX-variants due to a missense mutation in the FIX propeptide, either Ala-10Val or Ala-10Thr, has highlighted a novel type of genetic predisposition to bleeding during oral anticoag
Autor:
C L, Kempton, T C, Abshire, R A, Deveras, W K, Hoots, J C, Gill, C M, Kessler, N S, Key, B A, Konkle, P, Kuriakose, D E, Macfarlane, G, Bergman
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 18(5)
OBI-1 is a recombinant B-domain deleted porcine factor VIII (FVIII). FVIII treatment in those with haemophilia A may be complicated by the development of anti-FVIII antibodies (inhibitors) leading to a failure to respond to treatment with human FVIII
Autor:
M. Ullman, Michael B. Nichol, Christina Chen, Brenda Riske, Roshni Kulkarni, J Wu, M. Lou, JD Hord, Marion A. Koerper, Judith Baker, B. A. Konkle
Publikováno v:
Value in Health. 18:A682
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 17(5)
In older men with haemophilia, arthropathy resulting from a lifetime of intra-articular bleeding contributes to the loss of independence and increased morbidity that occurs with age. A regular exercise programme that incorporates aerobics, strength t
Autor:
G, Young, G, Auerswald, V, Jimenez-Yuste, B A, Konkle, T, Lambert, M, Morfini, E, Santagostino, V, Blanchette
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 17(5)
Currently, patients with severe haemophilia can expect to lead a relatively normal life including prevention of disabling arthropathy as a result of the development of factor replacement therapy and advances in the understanding of the use of such th
Autor:
J M, Soucie, C, Wang, A, Siddiqi, R, Kulkarni, M, Recht, B A, Konkle, Pattye Tobase, Zimmerman
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 17(2)
Although body adiposity and disease severity in haemophilia have been found in cross-sectional studies to be negatively associated with joint mobility, it is not clear how these two factors affect the rate of joint mobility loss over time. Over a 10-
Autor:
S. Lee, R. S. McKinley, Louis Bernatchez, B. R. Konkle, M. Gatt, M. L. Malott, Moira M. Ferguson
Publikováno v:
Journal of Fish Biology. 43:91-101
We analysed mitochondrial DNA (mtDNA) variation of lake sturgeon (Adpenser fulvescens) from the Moose River basin. Our objective was to address various proximate and ultimate factors which may influence the distribution of lake sturgeon mtDNA haploty