Zobrazeno 1 - 10
of 39
pro vyhledávání: '"B A, Handwerger"'
Autor:
I G, Luzina, S P, Atamas, C E, Storrer, L C, daSilva, G, Kelsoe, J C, Papadimitriou, B S, Handwerger
Publikováno v:
Journal of leukocyte biology. 70(4)
The mechanisms of autoantibody production are not well understood. Germinal centers (GC) may be important sites of immune disregulation in autoimmune diseases. In this study, we document the presence of spontaneous GC formation in the spleens of seve
Publikováno v:
Archives of ophthalmology (Chicago, Ill. : 1960). 119(1)
To investigate the safety and efficacy of low-dose intravitreal tissue plasminogen activator (tPA) and an expansile gas bubble in displacing submacular hemorrhage in patients with age-related macular degeneration (ARMD).We reviewed retrospectively th
Publikováno v:
Archives of ophthalmology (Chicago, Ill. : 1960). 118(12)
Autor:
I G, Luzina, R H, Knitzer, S P, Atamas, W C, Gause, J C, Papadimitriou, M B, Sztein, C E, Storrer, B S, Handwerger
Publikováno v:
Arthritis and rheumatism. 42(3)
To define the phenotype of cells in the perivascular and vascular infiltrates of Palmerston North (PN) mice and the cytokines that those cells produce.Immunohistologic analysis, flow cytometric analysis, and reverse transcriptase-polymerase chain rea
Publikováno v:
Journal of clinical immunology. 19(1)
PN mice spontaneously develop, with age, a lupus-like disease. The present study further evaluated autoantibody production in female PN mice. As early as 1 month of age, all PN mice had detectable IgM antibodies to dsDNA and ssDNA and two-thirds prod
Publikováno v:
Journal of pediatric psychology. 21(4)
Investigated the incidence and severity of Posttraumatic Stress Disorder (PTSD) in childhood cancer using informant methodology. The parents of pediatric cancer patients (n = 30) and off-treatment survivors (n = 42) completed a modified version of th
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(10)
We previously have shown that T cell proliferation in response to a primary signal through the CD3 epsilon chain and a costimulatory signal via the CD28 molecule is impaired in healthy, aged mice. To determine whether age-related alterations in cytok
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(8)
The ability of T cells to proliferate in response to a number of stimuli is impaired in healthy, aged individuals. T cells from young (2 to 4 mo) and aged (20 to 26 mo) mice were stimulated with immobilized anti-CD3 epsilon-chain mAb and soluble anti
Publikováno v:
Transplantation proceedings. 25(1 Pt 1)
Autor:
C S, Via, B S, Handwerger
Publikováno v:
Current opinion in rheumatology. 4(5)
B-cell hyperactivity is characteristic of lupus and appears to be, in many instances, T-cell driven. Recent work continues to examine the paradox of T-cell activation in vivo and depressed T-cell function in vitro. The role of intrinsic B-cell abnorm