Zobrazeno 1 - 10
of 12
pro vyhledávání: '"B A, Domin"'
Publikováno v:
Oncology research. 5(12)
3'-Azido-3'-deoxythymidine (AZT) competitively inhibited the transport of thymidine (Km = 0.23 mM) into human erythrocytes with a Ki of 1.0 mM at 37 degrees C. The principal human metabolite of AZT in plasma, the 5'-glucuronide (GAZT), was a weak inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4bdcf0fd1fead8e5a16cb295d398f978
https://pubmed.ncbi.nlm.nih.gov/8086670
https://pubmed.ncbi.nlm.nih.gov/8086670
Publikováno v:
The Journal of biological chemistry. 267(28)
Carbovir (9-[4 alpha-(hydroxymethyl)cyclopent-2-ene-1 alpha-yl]guanine) (CBV) is a carbocyclic analogue of 2',3'-dideoxyguanosine that exhibits potent and selective in vitro activity against human immunodeficiency virus. Antiviral activity is associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4cc2cfba0fc1fcffab26f5acc1d5ea32
https://pubmed.ncbi.nlm.nih.gov/1400293
https://pubmed.ncbi.nlm.nih.gov/1400293
Publikováno v:
Molecular pharmacology. 41(5)
The membrane permeation characteristics of 5'-deoxythymidine (5'-ddThd) and 5'-azido-5'-deoxythymidine (5'-N3-5'-ddThd) were investigated in human erythrocytes, with an inhibitor-stop assay, at 20 degrees. Uptake of both nucleoside analogs occurred w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc810992847236fc5373dbbd23b4cdbe
https://pubmed.ncbi.nlm.nih.gov/1588925
https://pubmed.ncbi.nlm.nih.gov/1588925
Publikováno v:
Molecular pharmacology. 21(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1401b44e45031a4bbcf727631a06d8b5
https://pubmed.ncbi.nlm.nih.gov/7132960
https://pubmed.ncbi.nlm.nih.gov/7132960
Publikováno v:
Cancer research. 46(2)
Placental tissues were obtained from Chinese women in Taiwan who had been exposed to contaminated rice oils containing polychlorinated biphenyls and their thermal degradative products. Exposure via the diet occurred 4-5 years prior to pregnancy. Plac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81224a2b49478d91083d42598924a2be
https://pubmed.ncbi.nlm.nih.gov/3079671
https://pubmed.ncbi.nlm.nih.gov/3079671
Publikováno v:
The Journal of biological chemistry. 263(19)
The mechanism of transport of the antiviral agent acyclovir (ACV) into human erythrocytes has been investigated. Initial velocities of ACV influx were determined with an "inhibitor-stop" assay that used papaverine to inhibit ACV influx rapidly and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1286127d2cad389347fa81c63e2b3bbf
https://pubmed.ncbi.nlm.nih.gov/3379070
https://pubmed.ncbi.nlm.nih.gov/3379070
Publikováno v:
Advances in experimental medicine and biology. 163
In the past few years we have been engaged in studying several folate cofactor requiring enzymes derived from human cells; namely thymidylate synthase, dihydrofolate reductase, folyl binder, 10-formyl-H4PteGlu synthetase, 5,10-methenyl-H4PteGlu cyclo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7066feb18ec6db0a14475aa9859143d0
https://pubmed.ncbi.nlm.nih.gov/6351556
https://pubmed.ncbi.nlm.nih.gov/6351556
Publikováno v:
Molecular pharmacology. 21(2)
A cloned subline of human cell variants derived from KB cells (KB/6b), 6500-fold resistant to methotrexate (MTX), exhibited a stable 40-fold elevation of the enzyme dihydrofolate reductase (EC 1.5.1.3., DHFR) in the absence of the drug. No difference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b78443081bc11611cb7b544c4231fba
https://pubmed.ncbi.nlm.nih.gov/7099148
https://pubmed.ncbi.nlm.nih.gov/7099148
Publikováno v:
Molecular pharmacology. 31(4)
The presence of homologues of rabbit cytochrome P-450 isozyme 5 in pulmonary and hepatic microsomal preparations from guinea pig, mouse, monkey, hamster, and rat was examined by immunoblotting and inhibition of metabolism of 2-aminofluorene with anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa204aeace1f1f61db4e44be9a7d949e
https://pubmed.ncbi.nlm.nih.gov/3574284
https://pubmed.ncbi.nlm.nih.gov/3574284
Publikováno v:
Molecular pharmacology. 30(3)
Enzyme components and activities of the cytochrome P-450 monooxygenase system in microsomal preparations from the Clara cell, alveolar type II cell, and alveolar macrophage fractions isolated from lungs of untreated rabbits and rabbits treated with 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28535ce0eb28f95483d984c6e638c3a8
https://pubmed.ncbi.nlm.nih.gov/3092027
https://pubmed.ncbi.nlm.nih.gov/3092027