Zobrazeno 1 - 10
of 15
pro vyhledávání: '"B A, Demeneix"'
Publikováno v:
Molecular and cellular endocrinology. 420
Adult neurogenesis occurs in neural stem cell (NSC) niches where slow cycling stem cells give rise to faster cycling progenitors. In the adult mouse NSC niche thyroid hormone, T3, and its receptor TRα act as a neurogenic switch promoting progenitor
Publikováno v:
Nucleosides and Nucleotides
Nucleosides and Nucleotides, 1997, 16 (7-9), pp.1121-1127. ⟨10.1080/07328319708006146⟩
ResearcherID
Nucleosides and Nucleotides, 1997, 16 (7-9), pp.1121-1127. ⟨10.1080/07328319708006146⟩
ResearcherID
International audience; Several non-permanent polycations possessing substantial buffering capacity below physiological pH, such as lipopolyamines and polyethylenimines, are efficient transfection agents per se, i.e. without the addition of lysosomot
Publikováno v:
Current topics in developmental biology. 103
Classically, thyroid hormones (THs) have been primarily associated with postembryonic development (Tata, 1968), notably metamorphosis in anuran amphibians and flat fish. This period is parallel to the perinatal period in man and many marked developme
Autor:
Michelle R. Embry, R Davi, Marc Léonard, Stefan Scholz, Patrick Renner, Daniel L. Villeneuve, J S Denny, Mark E. McMaster, Scott E. Belanger, B A Demeneix, F Busquet
Publikováno v:
Critical reviews in toxicology. 43(1)
Endocrine disruption is considered a highly relevant hazard for environmental risk assessment of chemicals, plant protection products, biocides and pharmaceuticals. Therefore, screening tests with a focus on interference with estrogen, androgen, and
Autor:
G F, Lemkine, B A, Demeneix
Publikováno v:
Current opinion in molecular therapeutics. 3(2)
Branched and linear polyethylenimines (PEIs) are proving to be efficient, non-toxic and versatile agents for in vivo gene delivery by a number of routes. A major factor in the successful use of PEIs seems to be the small size of PEI/DNA complexes whi
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 133
Publikováno v:
The International journal of developmental biology. 42(8)
The formulation of cationic polymers of polyethylenimine (PEI) with plasmid DNA has been optimized to deliver genes into the Xenopus tadpole brain in vivo. Using intraventricular microinjections of 1 microl (containing 0.5 to 1 microg DNA) we show th
Publikováno v:
Gene Therapy ISBN: 9783642721625
The mechanisms underlying the actions of polycationic (as opposed to monocationic) gene transfer vectors is described. Two main types of vectors are examined, polycationic amphiphiles such as DOGS (Transfectam™) and Lipofectamine on the one hand an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9be91d05d00a5c65d7823427c465cc5
https://doi.org/10.1007/978-3-642-72160-1_20
https://doi.org/10.1007/978-3-642-72160-1_20
Publikováno v:
Gene therapy. 3(5)
Nonviral gene transfer into the central nervous system could provide a basis for therapeutic uses and fundamental research. We show that naked DNA injected intracerebrally into the mouse brain can provide expression of a reporter protein. Expression
Publikováno v:
Biology of the cell. 85(1)
The main limitation of non-viral gene transfer methods is their relatively low efficiency in vivo. However, a number of approaches can be taken to improve their performances, whether the aim is studying gene function during development or employing t