Zobrazeno 1 - 10 of 49 pro vyhledávání: '"B A, Bopp"'
1
A young and complex binary star – HD 144432
Autor: M.E. van den Ancker, B. W. Bopp, D. de Winter, M. R. Pérez
Publikováno v: Astronomy & Astrophysics. 416:647-654
The southern emission-line star HD 144432 has received considerable attention due to its relative brightness (V ~ 8.17), its late spectral type (late A-type or perhaps early F) and its relative isolation from a bona-fide active star formation region.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9624cf5595b6cb05c4e43962253172f8
https://doi.org/10.1051/0004-6361:20034390
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2
Stereoselective pharmacokinetics of pazinaclone, a new non-benzodiazepine anxiolytic, and its active metabolite in healthy subjects
Autor: D. J. Mulford, B. A. Bopp, Z Hussein, G R Granneman
Publikováno v: British Journal of Clinical Pharmacology. 36:357-361
1. Serum and urine concentrations of enantiomers of pazinaclone (DN-2327) and an active metabolite MII, were measured after single and twice daily oral doses of 4 and 8 mg racemic drug to healthy subjects. 2. The kinetics of rac-pazinaclone and rac-M
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4240cdffc79d7884ba8771a5bc7ddba
https://doi.org/10.1111/j.1365-2125.1993.tb00376.x
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3
Mass Exchange Via Pulsational Dumping from and F Supergiant
Autor: S. B. Parsons, R. C. Dempsey, B. W. Bopp
Publikováno v: Symposium - International Astronomical Union. 151:341-344
HD 207739 = V1914 Cyg, a tidally distorted F8 supergiant plus an obscured hot non-degenerate star, is presently in a state of episodic mass dumping onto an accretion shell around the hot component. Unrelated to the 141 day orbital cycle, the obscurat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4d243134056112c68ad8a83699dd118
https://doi.org/10.1017/s0074180900122430
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4
Differences in the stereoselective pharmacokinetics of pazinaclone (DN-2327), a new anxiolytic, and its active metabolite after intravenous and oral single doses to dogs
Autor: Z, Hussein, D J, Mulford, B A, Bopp, G R, Granneman
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 21(5)
The stereoselective pharmacokinetics of the new nonbenzodiazepine anxiolytic compound pazinaclone (DN-2327) were studied in four beagle dogs after oral (2.5 mg/kg) and intravenous (0.5 mg/kg) administration of racemate in a two-way, crossover study d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bc3188dacb0ce0e215a0e5a2fe9f80c3
https://pubmed.ncbi.nlm.nih.gov/7902240
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6
Metabolism and disposition of clarithromycin in man
Autor: J L, Ferrero, B A, Bopp, K C, Marsh, S C, Quigley, M J, Johnson, D J, Anderson, J E, Lamm, K G, Tolman, S W, Sanders, J H, Cavanaugh
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 18(4)
The metabolic fate and pharmacokinetics of clarithromycin following a single 250- or 1200-mg oral dose of 14C-clarithromycin were studied in six healthy adult males. Peak plasma levels of clarithromycin averaged 0.6 microgram/ml after the low dose an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::54cad9719885e9b1111a542918321648
https://pubmed.ncbi.nlm.nih.gov/1976065
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8
Renin inhibitors. Dipeptide analogs of angiotensinogen utilizing a structurally modified phenylalanine residue to impart proteolytic stability
Autor: J J, Plattner, P A, Marcotte, H D, Kleinert, H H, Stein, J, Greer, G, Bolis, A K, Fung, B A, Bopp, J R, Luly, H L, Sham
Publikováno v: Journal of Medicinal Chemistry. 31:2277-2288
A series of renin inhibitors have been prepared and evaluated for their susceptibility to cleavage by the serine protease chymotrypsin. The compounds were designed by consideration of the structural requirements in the active-site region of renin and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9faaec357ae61d9f2f08fab4cd5437f3
https://doi.org/10.1021/jm00120a006
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9
Metabolism of14C-estazolam in dogs and humans
Autor: B A Bopp, R C Sonders, Douglas E. Rollins, D J Anderson, Kenneth N. Buchi, G R Granneman, J M Machinist, Keith G. Tolman
Publikováno v: Xenobiotica. 16:11-20
14C-Estazolam (2 mg) administered orally to dogs and human subjects was rapidly and completely absorbed with peak plasma levels occurring within one hour. In humans, plasma levels peaked at 103 +/- 18 ng/ml and declined monoexponentially with a half-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab7606c2031e03f7080aa9b8a4efce0
https://doi.org/10.3109/00498258609043501
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10
Metabolism of [14C]Cefmenoxime in normal subjects after intramuscular administration
Autor: J M Machinist, B A Bopp, D Quinn
The metabolism of cefmenoxime (SCE-1365) was studied in four healthy male volunteers after intramuscular administration of a single 500-mg dose of the 14C-labeled drug. Plasma levels of total radioactivity and cefmenoxime peaked at 0.5 and 1.0 h, cor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc1c843543b616d149fcfa83f897f86
https://europepmc.org/articles/PMC179939/
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