Zobrazeno 1 - 10
of 8 931
pro vyhledávání: '"B‐cell receptor"'
Autor:
Annika Katharina Breitfelder, Wieland Schrödl, Christoph Georg Baums, Gottfried Alber, Uwe Müller
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-16 (2024)
Abstract Streptococcus suis (S. suis) is one of the most important porcine pathogens, causing severe pathologies such as meningitis or polyarthritis. It is also a very successful colonizer of mucosal surfaces. The IgM-degrading enzyme of S. suis (Ide
Externí odkaz:
https://doaj.org/article/ea11274c33f84373b130286f19cb6b60
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1705-1714 (2024)
Camelids produce both conventional tetrameric antibodies (Abs) and dimeric heavy-chain antibodies (HCAbs). Although B cells that generate these two types of Abs exhibit distinct B cell receptors (BCRs), whether these two B cell populations differ in
Externí odkaz:
https://doaj.org/article/d5b2fdea9fcf4229bdc7c5dd0352f9d8
Autor:
Yohei Funakoshi, Kimikazu Yakushijin, Goh Ohji, Takaji Matsutani, Kazuhiko Doi, Hironori Sakai, Tomoki Sasaki, Takahiro Kusakabe, Sakuya Matsumoto, Yasuyuki Saito, Shinichiro Kawamoto, Katsuya Yamamoto, Taiji Koyama, Yoshiaki Nagatani, Keiji Kurata, Shiro Kimbara, Yoshinori Imamura, Naomi Kiyota, Mitsuhiro Ito, Hironobu Minami
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 661-668 (2024)
Abstract Monovalent Omicron XBB.1.5 mRNA vaccines were newly developed and approved by the FDA in Autumn 2023 for preventing COVID‐19. However, clinical efficacy for these vaccines is currently lacking. We previously established the quantification
Externí odkaz:
https://doaj.org/article/4e80912d8731416b882b2610fa7fdb8e
Autor:
Chidimma Agatha Akpa, Cora Husemann, Chris Allen, Ann-Christin von Brünneck, Jana Ihlow, Michael Hummel
Publikováno v:
Journal of Molecular Pathology, Vol 5, Iss 3, Pp 292-303 (2024)
Mucosa-associated lymphoid tissue (MALT) lymphomas are slow-growing B-cell lymphomas mainly diagnosed in the stomach and termed gastric MALT lymphoma (G-MALT). Despite histological evaluation, immunostaining, and additional B-cell clonality analysis
Externí odkaz:
https://doaj.org/article/54a98f4d2b744b7290557dee415bd454
Publikováno v:
生物医学转化, Vol 5, Iss 2, Pp 81-90 (2024)
B cells play a crucial role in recognizing external antigens through their surface B cell receptor (BCR), essential for generating protective antibodies and immune memory. Regulation of B cell immune activation is closely linked to various upper resp
Externí odkaz:
https://doaj.org/article/7f62dc16bd434bd0a7ce2cbd2408a543
Autor:
Goh Ohji, Yohei Funakoshi, Kimikazu Yakushijin, Takaji Matsutani, Tomoki Sasaki, Takahiro Kusakabe, Sakuya Matsumoto, Taiji Koyama, Yoshiaki Nagatani, Keiji Kurata, Shiro Kimbara, Naomi Kiyota, Hironobu Minami
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
A monovalent Omicron XBB.1.5 mRNA RBD analogue vaccine, MAFB-7256a (DS-5670d), was newly developed and approved in Japan in the Spring of 2024 for the prevention of COVID-19. However, clinical efficacy data for this vaccine are currently lacking. We
Externí odkaz:
https://doaj.org/article/59a011b3f9d04db7af323572148f920d
Autor:
Ethan Deitcher, Kirk Trisler, Branden S. Moriarity, Caleb J. Bostwick, Fleur A. D. Leenen, Steven R. Deitcher
Publikováno v:
BioMedInformatics, Vol 4, Iss 2, Pp 1384-1395 (2024)
Genome engineered B-cells are being developed for chronic, systemic in vivo protein replacement therapies and for localized, tumor cell-actuated anticancer therapeutics. For continuous systemic engineered protein production, expression may be driven
Externí odkaz:
https://doaj.org/article/767cf045505c4fcfb611e91e3b010a26
Autor:
Michelle Elbert, Frank Neumann, Maximilian Kiefer, Konstantinos Christofyllakis, Benedikt Balensiefer, Igor Kos, Gabi Carbon, Dominic Kaddu-Mulindwa, Joerg Thomas Bittenbring, Natalie Fadle, Evi Regitz, Falko Fend, Irina Bonzheim, Lorenz Thurner, Moritz Bewarder
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Primary vitreoretinal lymphoma (PVRL) is a rare subtype of DLBCL and can progress into primary central nervous system lymphoma (PCNSL). To investigate the role of chronic antigenic stimulation in PVRL, we cloned and expressed B-cell receptor
Externí odkaz:
https://doaj.org/article/ca3b6cea9f3443d09c6dc24e96584db7
Autor:
Sabrina Pollastro, Anne Musters, Giulia Balzaretti, Ilse Niewold, Barbera van Schaik, Signe Hässler, Catharina M. Verhoef, Marc Pallardy, Antoine van Kampen, Xavier Mariette, Niek de Vries, on behalf of the ABIRISK Consortium
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-10 (2024)
Abstract Background Although B-cell depleting therapy in rheumatoid arthritis (RA) is clearly effective, response is variable and does not correlate with B cell depletion itself. Methods The B-cell receptor (BCR) repertoire was prospectively analyzed
Externí odkaz:
https://doaj.org/article/ecdf69d1480741139ed72b2a3f836118
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
B cells surveil the body for foreign matter using their surface-expressed B cell antigen receptor (BCR), a tetrameric complex comprising a membrane-tethered antibody (mIg) that binds antigens and a signaling dimer (CD79AB) that conveys this interacti
Externí odkaz:
https://doaj.org/article/01e0ede57de04b9e9e729f528e89d11f