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Akademický článek

Cytomegalovirus inhibitors of programmed cell death restrict antigen cross-presentation in the priming of antiviral CD8 T cells.

Autor: Ebert S; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany., Böhm V; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany., Büttner JK; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany., Brune W; Leibniz Institute of Virology (LIV), Hamburg, Germany., Brinkmann MM; Institute of Genetics, Technische Universität Braunschweig, Braunschweig, Germany.; Virology and Innate Immunity Research Group, Helmholtz Centre for Infection Research, Braunschweig, Germany., Holtappels R; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.; Research Center for Immunotherapy (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany., Reddehase MJ; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.; Research Center for Immunotherapy (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany., Lemmermann NAW; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.; Research Center for Immunotherapy (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.; Institute of Virology, Medical Faculty, University of Bonn, Bonn, Germany.

Publikováno v: PLoS pathogens [PLoS Pathog] 2024 Aug 15; Vol. 20 (8), pp. e1012173. Date of Electronic Publication: 2024 Aug 15 (Print Publication: 2024).

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Akademický článek

Modulation of cytomegalovirus immune evasion identifies direct antigen presentation as the predominant mode of CD8 T-cell priming during immune reconstitution after hematopoietic cell transplantation.

Autor: Holtappels R; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Büttner JK; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Freitag K; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Reddehase MJ; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Lemmermann NA; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.; Institute of Virology, Medical Faculty, University of Bonn, Bonn, Germany.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Feb 15; Vol. 15, pp. 1355153. Date of Electronic Publication: 2024 Feb 15 (Print Publication: 2024).

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Akademický článek

Direct antigen presentation is the canonical pathway of cytomegalovirus CD8 T-cell priming regulated by balanced immune evasion ensuring a strong antiviral response.

Autor: Büttner JK; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Becker S; Institute of Virology, Medical Faculty, University of Bonn, Bonn, Germany., Fink A; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Brinkmann MM; Institute of Genetics, Technische Universität Braunschweig, Braunschweig, Germany.; Virology and Innate Immunity Research Group, Helmholtz Centre for Infection Research, Braunschweig, Germany., Holtappels R; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Reddehase MJ; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Lemmermann NA; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.; Institute of Virology, Medical Faculty, University of Bonn, Bonn, Germany.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Dec 12; Vol. 14, pp. 1272166. Date of Electronic Publication: 2023 Dec 12 (Print Publication: 2023).

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Akademický článek

Mast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungs.

Autor: Ebert S; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany., Becker M; Institute for Immunology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany., Lemmermann NA; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany., Büttner JK; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany., Michel A; Institute for Immunology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany., Taube C; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands., Podlech J; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany., Böhm V; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany., Freitag K; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany., Thomas D; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany., Holtappels R; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany., Reddehase MJ; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany., Stassen M; Institute for Immunology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

Publikováno v: PLoS pathogens [PLoS Pathog] 2014 Apr 24; Vol. 10 (4), pp. e1004100. Date of Electronic Publication: 2014 Apr 24 (Print Publication: 2014).

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Akademický článek

Noncanonical expression of a murine cytomegalovirus early protein CD8 T-cell epitope as an immediate early epitope based on transcription from an upstream gene.

Autor: Fink A; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, Obere Zahlbacher Str. 67, Mainz D-55131, Germany. finka@uni-mainz.de., Büttner JK; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, Obere Zahlbacher Str. 67, Mainz D-55131, Germany. julia_buettner@uni-mainz.de., Thomas D; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, Obere Zahlbacher Str. 67, Mainz D-55131, Germany. thomdo00@uni-mainz.de., Holtappels R; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, Obere Zahlbacher Str. 67, Mainz D-55131, Germany. R.Holtappels@uni-mainz.de., Reddehase MJ; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, Obere Zahlbacher Str. 67, Mainz D-55131, Germany. matthias.reddehase@uni-mainz.de., Lemmermann NA; Institute for Virology and Research Center for Immunology (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, Obere Zahlbacher Str. 67, Mainz D-55131, Germany. lemmermann@uni-mainz.de.

Publikováno v: Viruses [Viruses] 2014 Feb 14; Vol. 6 (2), pp. 808-31. Date of Electronic Publication: 2014 Feb 14.

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