Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Bürli RW"'
Autor:
Bürli RW; Cerevance Limited, 418 Cambridge Science Park, Cambridge, CB4 0PZ, United Kingdom., Doyle KJ; Cerevance Limited, 418 Cambridge Science Park, Cambridge, CB4 0PZ, United Kingdom., Dickson L; Cerevance Limited, 418 Cambridge Science Park, Cambridge, CB4 0PZ, United Kingdom., Rowland A; Cerevance Limited, 418 Cambridge Science Park, Cambridge, CB4 0PZ, United Kingdom., Matthews K; Cerevance Limited, 418 Cambridge Science Park, Cambridge, CB4 0PZ, United Kingdom., Stott AJ; Cerevance Limited, 418 Cambridge Science Park, Cambridge, CB4 0PZ, United Kingdom., Teall M; Cerevance Limited, 418 Cambridge Science Park, Cambridge, CB4 0PZ, United Kingdom., Ossola B; Cerevance Limited, 418 Cambridge Science Park, Cambridge, CB4 0PZ, United Kingdom., Russell SG; Cerevance Limited, 418 Cambridge Science Park, Cambridge, CB4 0PZ, United Kingdom., Harvey JRM; Cerevance Limited, 418 Cambridge Science Park, Cambridge, CB4 0PZ, United Kingdom., Wu Y; Wuxi Apptec Co., Ltd., 288 Fute Zhong Rd., Waigaoqiao, Shanghai 200131, People's Republic of China., Narayana L; Aragen Life Sciences Ltd, Plot #284A (part), Bommasandra-Jigani Link Road Industrial Area, Bengaluru 562106, India., Brice NL; Cerevance Limited, 418 Cambridge Science Park, Cambridge, CB4 0PZ, United Kingdom., Carlton M; Cerevance Limited, 418 Cambridge Science Park, Cambridge, CB4 0PZ, United Kingdom., Dawson LA; Cerevance Limited, 418 Cambridge Science Park, Cambridge, CB4 0PZ, United Kingdom.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2024 Apr 05; Vol. 15 (5), pp. 646-652. Date of Electronic Publication: 2024 Apr 05 (Print Publication: 2024).
Autor:
Glen A; Takeda Cambridge Ltd., 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Bürli RW; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Livermore D; Takeda Cambridge Ltd., 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Buffham W; Takeda Cambridge Ltd., 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Merison S; Takeda Cambridge Ltd., 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Rowland AE; Takeda Cambridge Ltd., 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Newman R; Takeda Cambridge Ltd., 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Fieldhouse C; Takeda Cambridge Ltd., 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Miller DJ; Takeda Cambridge Ltd., 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Dawson LA; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Matthews K; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Carlton MB; Takeda Cambridge Ltd., 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Brice NL; Takeda Cambridge Ltd., 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK. Electronic address: nicola.brice@cerevance.com.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2024 Mar 01; Vol. 100, pp. 129629. Date of Electronic Publication: 2024 Jan 30.
Autor:
Rifat A; Institute of Neurophysiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany., Ossola B; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Bürli RW; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Dawson LA; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Brice NL; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Rowland A; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Lizio M; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Xu X; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Page K; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Fidzinski P; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Department of Neurology, Epilepsy-Center Berlin-Brandenburg, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Neurocure Cluster of Excellence, Neuroscience Clinical Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany., Onken J; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Department of Neurosurgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany., Holtkamp M; Department of Neurology, Epilepsy-Center Berlin-Brandenburg, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany., Heppner FL; Neurocure Cluster of Excellence, Neuroscience Clinical Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Department of Neuropathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin, 10117, Berlin, Germany., Geiger JRP; Institute of Neurophysiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany., Madry C; Institute of Neurophysiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany. christian.madry@charite.de.
Publikováno v:
Journal of neuroinflammation [J Neuroinflammation] 2024 Feb 26; Vol. 21 (1), pp. 58. Date of Electronic Publication: 2024 Feb 26.
Autor:
Hewer RC; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Christie LA; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Doyle KJ; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Xu X; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Roberts MJ; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Dickson L; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Cheung T; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Cadwalladr DH; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Pickford P; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Teall M; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Powell JAC; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Sheardown S; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Narayana L; Aragen Life Sciences Ltd, Plot #284A (part), Bommasandra-Jigani Link Road Industrial Area, Bengaluru 562106, India., Brice NL; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Dawson LA; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Carlton M; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Bürli RW; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2023 Sep 28; Vol. 66 (18), pp. 12858-12876. Date of Electronic Publication: 2023 Sep 14.
Autor:
Christie LA; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom., Brice NL; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom., Rowland A; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom., Dickson L; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom., Anand R; Centre for Cellular and Molecular Neurobiology, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom., Teall M; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom., Doyle KJ; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom., Narayana L; Aragen Lifesciences Limited, Plot #284A (part), Bommasandra-Jigani Link Road Industrial Area, Bengaluru 562106, India., Mitchell C; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom., Harvey JRM; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom., Mulligan V; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom., Dawson LA; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom., Cragg SJ; Centre for Cellular and Molecular Neurobiology, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom., Carlton M; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom., Bürli RW; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, United Kingdom.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2023 Sep 14; Vol. 66 (17), pp. 11718-11731. Date of Electronic Publication: 2023 Aug 31.
Autor:
Dickson L; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Teall M; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Chevalier E; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Cheung T; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Liwicki GM; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Mack S; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Stephenson A; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., White K; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Fosbeary R; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Harrison DC; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Brice NL; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Doyle K; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Ciccocioppo R; School of Pharmacy, Pharmacology Unit, University of Camerino, Camerino 62032, Italy., Wu C; WuXi Apptec Limited, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China., Almond S; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Patel TR; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Mitchell P; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Barnes M; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Ayscough AP; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Dawson LA; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Carlton M; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K., Bürli RW; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2023 Mar 02; Vol. 14 (4), pp. 442-449. Date of Electronic Publication: 2023 Mar 02 (Print Publication: 2023).
Autor:
Ossola B; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK. Electronic address: dino.ossola@cerevance.com., Rifat A; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Neurophysiology, Charitéplatz 1, 10117 Berlin, Germany; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany., Rowland A; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Hunter H; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Drinkall S; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany., Bender C; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Hamlischer M; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Teall M; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Burley R; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Barker DF; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Cadwalladr D; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Dickson L; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Lawrence JMK; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Harvey JRM; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Lizio M; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Xu X; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Kavanagh E; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Cheung T; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Sheardown S; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Lawrence CB; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; Geoffrey Jefferson Brain Research Centre, The Manchester Academic Health Science Centre, Northern Care Alliance NHS Group, University of Manchester, Manchester, UK; The Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, UK., Harte M; Division of Pharmacy & Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; The Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, UK., Brough D; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; Geoffrey Jefferson Brain Research Centre, The Manchester Academic Health Science Centre, Northern Care Alliance NHS Group, University of Manchester, Manchester, UK; The Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, UK., Madry C; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Neurophysiology, Charitéplatz 1, 10117 Berlin, Germany., Matthews K; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Doyle K; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Page K; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Powell J; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Brice NL; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Bürli RW; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Carlton MB; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK., Dawson LA; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, CB4 0PZ, UK.
Publikováno v:
Neuropharmacology [Neuropharmacology] 2023 Feb 15; Vol. 224, pp. 109330. Date of Electronic Publication: 2022 Nov 12.
Autor:
Wrobel L; Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom.; UK Dementia Research Institute, University of Cambridge, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom., Hill SM; Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom.; UK Dementia Research Institute, University of Cambridge, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, 413 45, Gothenburg, Sweden., Djajadikerta A; Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom.; UK Dementia Research Institute, University of Cambridge, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom., Fernandez-Estevez M; Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom.; UK Dementia Research Institute, University of Cambridge, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom., Karabiyik C; Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom.; UK Dementia Research Institute, University of Cambridge, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom., Ashkenazi A; Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom., Barratt VJ; Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom.; UK Dementia Research Institute, University of Cambridge, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom., Stamatakou E; Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom.; UK Dementia Research Institute, University of Cambridge, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom., Gunnarsson A; Biophysics SE, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Rasmusson T; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Boston, MA, USA., Miele EW; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Boston, MA, USA., Beaton N; Biognosys AG, Wagistrasse 21, 8952, Schlieren, Switzerland., Bruderer R; Biognosys AG, Wagistrasse 21, 8952, Schlieren, Switzerland., Feng Y; Biognosys AG, Wagistrasse 21, 8952, Schlieren, Switzerland., Reiter L; Biognosys AG, Wagistrasse 21, 8952, Schlieren, Switzerland., Castaldi MP; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Boston, MA, USA., Jarvis R; Discovery UK, Neuroscience, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Tan K; Discovery UK, Neuroscience, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Bürli RW; Discovery UK, Neuroscience, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Rubinsztein DC; Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom. dcr1000@cam.ac.uk.; UK Dementia Research Institute, University of Cambridge, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, United Kingdom. dcr1000@cam.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2022 Jul 16; Vol. 13 (1), pp. 4146. Date of Electronic Publication: 2022 Jul 16.
Autor:
Burley R; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Hewer RC; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Teall M; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Dickson L; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Ossola B; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Russell S; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Bender C; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Cheung T; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Powell JAC; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Xu X; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Brice NL; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Otter L; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Arimont M; PharmEnable Ltd, 2 Hazlewell Court, Bar Road, Lolworth, Cambridge CB23 8DS, UK., Kidd SL; PharmEnable Ltd, 2 Hazlewell Court, Bar Road, Lolworth, Cambridge CB23 8DS, UK., Vidal D; PharmEnable Ltd, 2 Hazlewell Court, Bar Road, Lolworth, Cambridge CB23 8DS, UK., Dale JW; PharmEnable Ltd, 2 Hazlewell Court, Bar Road, Lolworth, Cambridge CB23 8DS, UK., Mervin L; PharmEnable Ltd, 2 Hazlewell Court, Bar Road, Lolworth, Cambridge CB23 8DS, UK., Sore HF; PharmEnable Ltd, 2 Hazlewell Court, Bar Road, Lolworth, Cambridge CB23 8DS, UK., Mateu N; PharmEnable Ltd, 2 Hazlewell Court, Bar Road, Lolworth, Cambridge CB23 8DS, UK., Lakshminarayana N; Aragen Life Sciences Ltd, Plot #284A (part), Bommasandra-Jigani Link Road Industrial Area, Bengaluru 562106, India., Dawson LA; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Carlton M; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK., Bürli RW; Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK. Electronic address: roland.burli@cerevance.com.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2022 Apr 01; Vol. 61, pp. 128607. Date of Electronic Publication: 2022 Feb 03.
Autor:
Hill SM; Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Cambridge, UK.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.; UK Dementia Research Institute, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Wrobel L; Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Cambridge, UK.; UK Dementia Research Institute, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Ashkenazi A; Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Cambridge, UK.; UK Dementia Research Institute, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.; Faculty of Medicine, Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel., Fernandez-Estevez M; Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Cambridge, UK.; UK Dementia Research Institute, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Tan K; Neuroscience, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Bürli RW; Neuroscience, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Rubinsztein DC; Department of Medical Genetics, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Cambridge, UK. dcr1000@cam.ac.uk.; UK Dementia Research Institute, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK. dcr1000@cam.ac.uk.
Publikováno v:
Nature chemical biology [Nat Chem Biol] 2021 Apr; Vol. 17 (4), pp. 448-455. Date of Electronic Publication: 2021 Jan 28.