Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Børge Thing Mortensen"'
Publikováno v:
Scandinavian Journal of Haematology. 30:235-246
Human bone marrow cells from normal subjects were density-separated in continuous density gradients of the Percoll medium. The distribution of cells showed a linear relationship between morphologic maturation and increasing density. The method was us
Publikováno v:
European Journal of Haematology. 48:202-207
Administration of both glycosylated and non-glycosylated recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) induces an immediate transient granulocytopenia of 1-3 hours' duration. In order to explore this phenomenon, granul
Publikováno v:
European Journal of Haematology. 42:77-83
The use of semi-solid cultures of bone marrow cells is briefly reviewed. In the last two decades this technique has greatly improved our understanding of the hierarchical structure of cell production and its regulatory factors. It is now well establi
Autor:
Peter Østrup Jensen, R.J. Hodgkiss, N. Helledie, J. K. Larsen, Ib Jarle Christensen, Børge Thing Mortensen, Per Ole Iversen
Publikováno v:
Cell Proliferation. 33:381-395
The microenvironmental changes in the bone marrow, spleen and liver during progression of the transplantable promyelocytic leukaemia in the Brown Norwegian rat (BNML) have been studied. We used flow cytometry to estimate cellular hypoxia and prolifer
Autor:
Kristina Carlson, Bengt Simonsson, Agneta Swedin, Christensen Ld, Børge Thing Mortensen, Britt Thuresson, JF Sällström, P Gimsing, Ulf Thunberg, Jan Westin, Carsten Geisler, Christer Sundström, Niels Smedegaard Andersen, Stig Lenhoff, M Bånghagen, Tor Olofsson, Mats Bengtsson
Publikováno v:
British Journal of Haematology. 104:546-552
In 30 patients with multiple myeloma who were scheduled for peripheral blood stem-cell transplantation, a quantitative analysis of the stem cells following enrichment by anti-CD34 was carried out. To detect the cells of the specific myeloma clone, po
Autor:
Peter Østrup Jensen, Niels Helledie, Børge Thing Mortensen, Per Ole Iversen, Mads Thorup Madsen, Elisabeth Ralfkiaer, Jørgen K. Larsen
Publikováno v:
British Journal of Haematology. 102:458-464
The Brown Norwegian rat transplanted with promyelocytic leukaemic cells (BNML) has been used as a model for human acute myeloid leukaemia. We have previously shown that both the blood supply to the bone marrow and the metabolic rate decrease in relat
Publikováno v:
Cytometry. 12:429-437
Washless methods for double staining of nuclear antigen and DNA in unfixed nuclei were compared with established methods for staining of fixed cells. The methods were tested on phytohemagglutinin (PHA)-stimulated normal human blood lymphocytes for th
Autor:
Christian H. Geisler, Børge Thing Mortensen, Nis I. Nissen, Marcus Diamant, Peter Østrup Jensen, Peter De Nully
Publikováno v:
Leukemialymphoma. 34(3-4)
Interleukin-6 (IL-6) has in vitro demonstrated growth regulatory effects on tumor cells from patients with chronic lymphocytic leukemia (CLL) and lymphoma. The proliferation rate of these cells is usually very low and this is thought to be one of the
Autor:
Nis I. Nissen, Doris Hovgaard, Peter Østrup Jensen, Peter Gimsing, Marcus Diamant, Børge Thing Mortensen, Peter de Nully Brown
Publikováno v:
Leukemia research. 22(11)
The plasma cell labeling index (PCLI) in patients with multiple myeloma (MM) is relatively low and this has been associated with the low rate of remission following chemotherapy. Interleukin-6 (IL-6) has been demonstrated to be a major growth factor
Publikováno v:
British journal of haematology. 91(2)
The pharmacokinetics and the pharmacodynamic profile of subcutaneously administered recombinant human non-glycosylated interleukin-3 (rhIL-3) was studied in lymphoma patients after standard CHOP chemotherapy. 30 patients received 0.5, 1.0, 5.0, 7.5 a