The role of granzymes in natural killer cell cytotoxicity

Autor: Bönnemann, Vivian

Natural killer (NK) cells are innate immune cells that defend the human body against viral infections and tumor growth. NK cells exhibit two pathways to kill aberrant cells: the granule-mediated pathway and the death receptor-mediated pathway. Upon t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be46c131edb201f6573e0914a9e366c1

ANALYSIS OF NATURAL KILLER CELL FUNCTIONS IN PATIENTS WITH HEREDITARY HEMOCHROMATOSIS.

Autor: Bönnemann, Vivian¹, Claus, Maren¹, Butzeck, Barbara², Collette, Daniela³, Bröde, Peter¹, Golka, Klaus¹, Watzl, Carsten¹ watzl@ifado.de

Publikováno v: EXCLI Journal. 2020, Vol. 19, Following p430-441. 14p.

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Analyzing the activity of the proteases granzyme B and caspase-8 inside living cells using fluorescence localization reporters.

Autor: Bruning N; Department of Immunology, Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund (IfADo), Dortmund, Germany., Bönnemann V; Department of Immunology, Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund (IfADo), Dortmund, Germany., Watzl C; Department of Immunology, Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund (IfADo), Dortmund, Germany. Electronic address: watzl@ifado.de.

Publikováno v: Methods in cell biology [Methods Cell Biol] 2023; Vol. 178, pp. 13-24. Date of Electronic Publication: 2022 Nov 03.