Zobrazeno 1 - 10
of 3 989
pro vyhledávání: '"Böger, P."'
Autor:
Juliane Hannemann, Anne Zink, Yoana Mileva, Paul Balfanz, Edgar Dahl, Sonja Volland, Thomas Illig, Edzard Schwedhelm, Florian Kurth, Alexandra Stege, Martin Aepfelbacher, Armin Hoffmann, Rainer Böger
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Mortality of patients hospitalized with COVID-19 has remained high during the consecutive SARS-CoV-2 pandemic waves. Early discrimination of patients at high mortality risk is crucial for optimal patient care. Symmetric (SDMA) and asymmetric
Externí odkaz:
https://doaj.org/article/fd19c5f66dfd4915bcc8f54205a52bc6
Autor:
Juliane Hannemann, Katrin Wasser, Yoana Mileva, Fiona Kleinsang, Mario Schubert, Edzard Schwedhelm, Kaomei Guan, Rolf Wachter, Rainer Böger
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 17 (2024)
Background Atrial fibrillation (AF) is a stroke risk factor that often remains undetected at hospital admission. Long‐term Holter monitoring helps to identify patients with previously unrecognized AF. Asymmetric (ADMA) and symmetric dimethylarginin
Externí odkaz:
https://doaj.org/article/70f7f2dad8af4eb195e2aa580ffe32bb
Autor:
Rainer Böger, Juliane Hannemann
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Chronic obstructive lung disease (COPD) has diverse molecular pathomechanisms and clinical courses which, however, are not fully mirrored by current therapy. Intermittent hypoxemia is a driver of lung function decline and poor out
Externí odkaz:
https://doaj.org/article/d9828a6540524740ae304f018bacaa33
Autor:
Mussab Kouka, Louise Beckmann, Thomas Bitter, Holger Kaftan, Daniel Böger, Jens Büntzel, Andreas Müller, Kerstin Hoffmann, Jiri Podzimek, Klaus Pietschmann, Thomas Ernst, Orlando Guntinas-Lichius
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Prognostic factors for overall survival (OS), percutaneous endoscopic gastrostomy (PEG) dependency, and long-term speech rehabilitation via voice prosthesis (VP) after laryngectomy for laryngeal or hypopharyngeal cancer were investigated in
Externí odkaz:
https://doaj.org/article/8ce4a11203764520bb18d29168cedfa0
Autor:
Afshin Saffari, Barbara Brechmann, Cedric Böger, Wardiya Afshar Saber, Hellen Jumo, Dosh Whye, Delaney Wood, Lara Wahlster, Julian E. Alecu, Marvin Ziegler, Marlene Scheffold, Kellen Winden, Jed Hubbs, Elizabeth D. Buttermore, Lee Barrett, Georg H. H. Borner, Alexandra K. Davies, Darius Ebrahimi-Fakhari, Mustafa Sahin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Unbiased phenotypic screens in patient-relevant disease models offer the potential to detect therapeutic targets for rare diseases. In this study, we developed a high-throughput screening assay to identify molecules that correct aberrant pro
Externí odkaz:
https://doaj.org/article/b52e18bceed849439f7ec10f0de5714b
Autor:
Alexandre de F. Cobre, Beatriz Böger, Mariana M. Fachi, Carlos A. Ehrenfried, Dile P. Stremel, Eduardo B. De Melo, Fernanda S. Tonin, Roberto Pontarolo
Publikováno v:
Química Nova, Vol 46, Iss 5, Pp 450-459 (2023)
To identify natural bioactive compounds (NBCs) as potential inhibitors of spike (S1) by means of in silico assays. NBCs with previously proven biological in vitro activity were obtained from the ZINC database and analyzed through virtual screening an
Externí odkaz:
https://doaj.org/article/20c1f272d1fe43418e25d30f05a7f663
Autor:
Emanuela Sozio, Juliane Hannemann, Martina Fabris, Adriana Cifù, Andrea Ripoli, Francesco Sbrana, Demetrio Cescutti, Luigi Vetrugno, Stefano Fapranzi, Flavio Bassi, Massimo Sponza, Francesco Curcio, Carlo Tascini, Rainer Böger
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract We aimed to assess the potential role of Asymmetric dimethylarginine (ADMA) in conditioning respiratory function and pulmonary vasoregulation during Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) infection. Within 72 h from admi
Externí odkaz:
https://doaj.org/article/0d207431a7de46259fe6b999e6c9f596
Autor:
Gianina Ungurean, Mehdi Behroozi, Leonard Böger, Xavier Helluy, Paul-Antoine Libourel, Onur Güntürkün, Niels C. Rattenborg
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Mammalian sleep has been implicated in maintaining a healthy extracellular environment in the brain. During wakefulness, neuronal activity leads to the accumulation of toxic proteins, which the glymphatic system is thought to clear by flushi
Externí odkaz:
https://doaj.org/article/7e5f9d7a52b947c9beac6798f6cb60c0
Autor:
Vinitha N. Ragavan, Pramod C. Nair, Natalia Jarzebska, Ramcharan Singh Angom, Luana Ruta, Elisa Bianconi, Silvia Grottelli, Natalia D. Tararova, Daniel Ryazanskiy, Steven R. Lentz, Sara Tommasi, Jens Martens-Lobenhoffer, Toshiko Suzuki-Yamamoto, Masumi Kimoto, Elena Rubets, Sarah Chau, Yingjie Chen, Xinli Hu, Nadine Bernhardt, Peter M. Spieth, Norbert Weiss, Stefan R. Bornstein, Debabrata Mukhopadhyay, Stefanie M. Bode-Böger, Renke Maas, Ying Wang, Antonio Macchiarulo, Arduino A. Mangoni, Barbara Cellini, Roman N. Rodionov
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Dimethylarginine dimethylaminohydrolase 1 (DDAH1) protects against cardiovascular disease by metabolising the risk factor asymmetric dimethylarginine (ADMA). However, the question whether the second DDAH isoform, DDAH2, directly metabolises
Externí odkaz:
https://doaj.org/article/c46891e5d10241cf95a530af2ca4d6b5
Autor:
Juliane Hannemann, Anika Laing, Benita Middleton, Edzard Schwedhelm, Nikolaus Marx, Massimo Federici, Mariola Kastner, Debra J. Skene, Rainer Böger
Publikováno v:
Pharmacological Research, Vol 199, Iss , Pp 107011- (2024)
Background: Night shift work is associated with sleep disturbances, obesity, and cardiometabolic diseases. Disruption of the circadian clock system has been suggested to be an independent cause of type 2 diabetes and cardiovascular disease in shift w
Externí odkaz:
https://doaj.org/article/f2bd3e984fb94d8ab3370c4ffe1d0116