Evaluation of the DOAC-Stop® Procedure to Overcome the Effect of DOACs on Several Thrombophilia Screening Tests

Autor: Julien Favresse, Benjamin Lardinois, Lina Sabor, Bérangère Devalet, Julie Vandepapeliere, Maximilien Braibant, Sarah Lessire, Bernard Chatelain, Hugues Jacqmin, Jonathan Douxfils, François Mullier

Publikováno v: TH Open, Vol 02, Iss 02, Pp e202-e209 (2018)

The impact of direct oral anticoagulants (DOACs) on laboratory assays used for thrombophilia testing (e.g., antithrombin, protein S, protein C, lupus anticoagulant and activated protein-C resistance) is a well-known issue and may cause false-positive

Externí odkaz: https://doaj.org/article/cb5cdb1115bb4c6ea5bea490dca486eb

Assessment of the analytical performances and sample stability on ST Genesia system using the STG‐DrugScreen application

Autor: Justine Baudar, Maïté Guldenpfennig, Marie de Saint-Hubert, Céline Bouvy, Jonathan Douxfils, Jean-Michel Dogné, François Mullier, Célia Devroye, Sarah Lessire, Laure Morimont, Bérangère Devalet, Anne-Sophie Larock, Anne-Sophie Dincq

Publikováno v: Journal of thrombosis and haemostasis : JTH, Vol. 17, no. 8, p. 1273-1287 (2019)
Journal of Thrombosis and Haemostasis
Douxfils, J, Morimont, L, Bouvy, C, de Saint-Hubert, M, Devalet, B, Devroye, C, Dincq, A-S, Dogné, J-M, Guldenpfennig, M, Baudar, J, Larock, A-S, Lessire, S & Mullier, F 2019, ' Assessment of the analytical performances and sample stability on ST Genesia system using the STG-DrugScreen application ', Journal of thrombosis and haemostasis : JTH, vol. 17, no. 8, pp. 1273-1287 . https://doi.org/10.1111/jth.14470

Background: Thrombin generation testing has been used to provide information on the coagulation phenotype of patients. The most used technique is the calibrated automated thrombogram (CAT) but it suffers from a lack of standardization, preventing its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21260c23ba4c5d3916ced2d2a3fbb5a1
https://doi.org/10.1111/jth.14470

Eculizumab decreases the procoagulant activity of extracellular vesicles in paroxysmal nocturnal hemoglobinuria

Autor: Benoît Bihin, Bernard Chatelain, Christian Chatelain, François Mullier, Adeline Wannez, Jean-Michel Dogné, Julie Laloy, Céline Bouvy, Bérangère Devalet

Publikováno v: Thrombosis Research. 156:142-148

Introduction Paroxysmal nocturnal hemoglobinuria (PNH) is a disease characterized by the susceptibility of blood cells to attack by the complement system, inducing extracellular vesicle (EV) production. Thromboembolism is the leading cause of death i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4870055f452421971e7f903d24725e9c
https://doi.org/10.1016/j.thromres.2017.06.013

Prospective and comparative study of paroxysmal nocturnal hemoglobinuria patients treated or not by eculizumab:Focus on platelet extracellular vesicles

Autor: Christian Chatelain, Bernard Chatelain, Benoît Bihin, Nicolas Bailly, Jonathan Douxfils, Lütfiye Alpan, Bérangère Devalet, Damien Gheldof, Adeline Wannez, Jean-Michel Dogné, François Mullier

Publikováno v: Devalet, B, Wannez, A, Bailly, N, Alpan, L, Gheldof, D, Douxfils, J, Bihin, B, Chatelain, B, Dogné, J-M, Chatelain, C & Mullier, F 2019, ' Prospective and comparative study of paroxysmal nocturnal hemoglobinuria patients treated or not by eculizumab : Focus on platelet extracellular vesicles ', Medicine (Mumbai): analytical reviews of general medicine, neurology, psychiatry, dermatology and pediatrics, vol. 98, no. 27, pp. e16164 . https://doi.org/10.1097/MD.0000000000016164
Medicine
Medicine, Vol. 98, no. 27, p. e16164 [1-8] (2019)

Thrombosis are severe complications of paroxysmal nocturnal hemoglobinuria (PNH), effectively reduced by eculizumab. Extracellular vesicles (EVs) may play a central role. The objective of this study was to assess the procoagulant activity of plasma i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7dfddadc43392bb80e7c86ddebc1f6
https://pure.unamur.be/ws/files/40063344/DevaletMedicine2019.pdf

Diagnosis and management of PNH: Review and recommendations from a Belgian expert panel

Autor: Nancy Boeckx, Bernard Chatelain, Bérangère Devalet, Stef Meers, Timothy Devos, André Gothot, Christian Chatelain, Dries Deeren

Publikováno v: European journal of haematology. 101(6)

Despite its considerable morbidity and mortality, paroxysmal nocturnal haemoglobinuria (PNH) is still underdiagnosed. Patients with PNH can suffer from cardiovascular, gastrointestinal, neurological or haematological symptoms and refer to several spe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002b3d8e4c6aadc616132810fd9c8d29
https://pubmed.ncbi.nlm.nih.gov/30171728