Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Bénédicte Hugel"'
Autor:
Jean-Marie Freyssinet, Nicolas Morel, Bénédicte Hugel, J. F. Cochard, Laurent Petit, Olivier Morel, François Sztark, P. Dabadie
Publikováno v:
Journal of Trauma: Injury, Infection & Critical Care. 64:698-704
Background: Traumatic brain injury (TBI) can induce cell damage. Procoagulant microparticles (MPs) are reliable markers of cell stimulation. The aim of this study was to investigate the generation of procoagulant MPs in the cerebrospinal fluid (CSF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db92211b1b062679d0217734105f3c3f
https://doi.org/10.1097/ta.0b013e31816493ad
https://doi.org/10.1097/ta.0b013e31816493ad
Autor:
Sandra Janower, Bénédicte Hugel, Alain Tedgui, Catherine Meuleman, Ziad Mallat, Ariel Cohen, Stéphane Ederhy, Emanuele Di Angelantonio, Jean-Marie Freyssinet, Franck Boccara
Publikováno v:
The American Journal of Cardiology. 100:989-994
Circulating procoagulant microparticles (MPs) arising from cell activation or fragmentation during apoptosis retain procoagulant properties and are increased in severe thrombotic states. We investigated whether circulating procoagulant MP levels woul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8d2a0710897521c215432860832b43
https://doi.org/10.1016/j.amjcard.2007.04.040
https://doi.org/10.1016/j.amjcard.2007.04.040
Autor:
Gilles Chironi, Jean-Marie Freyssinet, Muriel Del Pino, Alain Simon, Jérôme Gariepy, Alain Tedgui, Bénédicte Hugel
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 26:2775-2780
Objective— To clarify circulating microparticles (MP) relationships with preclinical atherosclerosis. Methods and Results— In 216 subjects without cardiovascular disease, we assessed: (1) annexin V-positive, platelet-derived, endothelium-derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9710f0c0b1efaf3d38cec5089ab7b1aa
https://doi.org/10.1161/01.atv.0000249639.36915.04
https://doi.org/10.1161/01.atv.0000249639.36915.04
Autor:
Angela Tesse, Bénédicte Hugel, Karel Chalupsky, Ramaroson Andriantsitohaina, Delia Mitolo-Chieppa, Jean-Marie Freyssinet, Christian D. Muller, Ferhat Meziani, M. Carmen Martinez
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 25:2522-2527
Objective—Microparticles are membrane vesicles with procoagulant and proinflammatory properties released during cell activation, including apoptosis. The present study was designed in dissecting the effects evoked by microparticles on vascular reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639362068d540c10e6c8431ad8e4c9ae
https://doi.org/10.1161/01.atv.0000189298.62240.5d
https://doi.org/10.1161/01.atv.0000189298.62240.5d
Autor:
Kathryn F. Carruthers, Ziad Mallat, Carla Sibella Arguelles, Keith A.A. Fox, Jean-Marie Freyssinet, Marie-Laure Tanguy, Joelle Benessiano, Bénédicte Hugel, Anne Dauphin, Joelle Masliah, Patrick Henry, Bernard Asselain, Phillippe Gabriel Steg, Omar H. Dabbous, Gilles Montalescot, Jean-Philippe Collet, Alain Tedgui
Publikováno v:
Journal of the American College of Cardiology. 46(7):1249-1257
OBJECTIVES The purpose of this study was to determine the prognostic value of circulating secretory phospholipase A2 (sPLA2) activity in patients with acute coronary syndromes (ACS). BACKGROUND The plasma level of type IIA sPLA2 is a risk factor for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8622c5c940210e9b893d480f6535c9bf
Autor:
Bénédicte Hugel, T. Blättler, Corinne Kunzelmann, Adriano Aguzzi, Jean-Marie Freyssinet, Maria Carmen Martinez
Publikováno v:
Cellular and Molecular Life Sciences. 61:2998-3007
Because expressed at a significant level at the membrane of human T cells, we made the hypothesis that the cellular prion protein (PrPc) could behave as a receptor, and be responsible for signal transduction. PrPc engagement by specific antibodies wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee4bf503023c1b52444b7e5d526abd4
https://doi.org/10.1007/s00018-004-4318-2
https://doi.org/10.1007/s00018-004-4318-2
Autor:
Thomas Geeraerts, Philippe Leclerc, Hassan Salim, Marc Tardieu, Bénédicte Hugel, Jean-Marie Freyssinet, Christiane Hery, Kumaran Deiva
Publikováno v:
European Journal of Neuroscience. 20:3222-3232
Our purpose was to investigate in human neurons the neuroprotective pathways induced by Fractalkine (FKN) against glutamate receptor-induced excitotoxicity. CX(3)CR1 and FKN are expressed constitutively in the tested human embryonic primary neurons a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b056f36dbd917472689725f257ffd14c
https://doi.org/10.1111/j.1460-9568.2004.03800.x
https://doi.org/10.1111/j.1460-9568.2004.03800.x
Autor:
Kaori Sato, Ramon G. Bonegio, Ian R. Rifkin, Kenneth Walsh, Tamar Aprahamian, John J. Castellot, Jean-Marie Freyssinet, Bénédicte Hugel
Publikováno v:
The Journal of Experimental Medicine
To clarify the link between autoimmune disease and hypercholesterolemia, we created the gld.apoE−/− mouse as a model of accelerated atherosclerosis. Atherosclerotic lesion area was significantly increased in gld.apoE−/− mice compared with apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e83932a129afe10a96a419ff83b2eca
https://doi.org/10.1084/jem.20031557
https://doi.org/10.1084/jem.20031557
Autor:
Michel Chauvin, Florence Toti, Bénédicte Hugel, Michel Zupan, Olivier Morel, Jean-Marie Freyssinet, Laurence Jesel, François Lanza, Jean-Pierre Cazenave, Marie-Pierre Douchet
Publikováno v:
Thrombosis and Haemostasis. 91:345-353
SummaryDuring myocardial infarction (MI), platelet activation and endothelial apoptosis are responsible for the release of procoagulant membrane-derived microparticles (MP) in the blood flow. MP prothrombotic and proinflammatory properties may be cru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67e3280a5907f5f976e5b4b0b8e3a01
https://doi.org/10.1160/th03-05-0294
https://doi.org/10.1160/th03-05-0294
Autor:
Bénédicte Hugel, J M Freyssinet, V. Eschwège, V. Mairovitz, R. Frydman, Martine Wolf, Dominique Meyer, C. Rongières-Bertrand, Catherine Boyer-Neumann, I. Laude
Publikováno v:
Thrombosis and Haemostasis. 85:18-21
SummaryOne of the frequently proposed mechanisms for pregnancy losses refers to uteroplacental thrombosis. However the contribution of classical thrombotic risk factors remains questionable and, if real, does not account for a large number of pregnan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37a9990d7516ea14171ff85af86e1937
https://doi.org/10.1055/s-0037-1612657
https://doi.org/10.1055/s-0037-1612657