Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bénédicte Demeulder"'
Autor:
Roselle Gélinas, Florence Mailleux, Justine Dontaine, Laurent Bultot, Bénédicte Demeulder, Audrey Ginion, Evangelos P. Daskalopoulos, Hrag Esfahani, Emilie Dubois-Deruy, Benjamin Lauzier, Chantal Gauthier, Aaron K. Olson, Bertrand Bouchard, Christine Des Rosiers, Benoit Viollet, Kei Sakamoto, Jean-Luc Balligand, Jean-Louis Vanoverschelde, Christophe Beauloye, Sandrine Horman, Luc Bertrand
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
AMPK activation inhibits cardiac hypertrophy. Here the authors show that this occurs independently of previously proposed mechanisms and that AMPK controls the phosphorylation of the aminotransferase GFAT, thereby preventing cardiac hypertrophy throu
Externí odkaz:
https://doaj.org/article/46a09b637dfb42aab34016e0737a3bb6
Autor:
Kei Sakamoto, Sandrine Horman, Roselle Gélinas, Benjamin Lauzier, Audrey Ginion, Bertrand Bouchard, Laurent Bultot, Hrag Esfahani, Jean-Luc Balligand, Emilie Dubois-Deruy, Aaron K Olson, Bénédicte Demeulder, Christophe Beauloye, Benoit Viollet, Evangelos-Panagiotis Daskalopoulos, Christine Des Rosiers, Justine Dontaine, Jean-Louis Vanoverschelde, Luc Bertrand, Florence Mailleux, C. Gauthier
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.374. ⟨10.1038/s41467-017-02795-4⟩
Nature Communications, Vol. 9, no. 1, p. 374 [1-17] (2018)
Nature Communications, 2018, 9 (1), pp.374. ⟨10.1038/s41467-017-02795-4⟩
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.374. ⟨10.1038/s41467-017-02795-4⟩
Nature Communications, Vol. 9, no. 1, p. 374 [1-17] (2018)
Nature Communications, 2018, 9 (1), pp.374. ⟨10.1038/s41467-017-02795-4⟩
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
AMP-activated protein kinase (AMPK) has been shown to inhibit cardiac hypertrophy. Here, we show that submaximal AMPK activation blocks cardiomyocyte hypertrophy without affecting downstream targets previously suggested to be involved, such as p70 ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8730038aa8097c3db15d238f852dc83
https://doi.org/10.1038/s41467-017-02795-4
https://doi.org/10.1038/s41467-017-02795-4
Autor:
Nicolas Pierre, Simon Vanmechelen, Bénédicte Demeulder, Pauline Regnier, Rodrigo Fernández-Verdejo, Marc Francaux
Publikováno v:
Cell Biology International. 40:91-99
Endoplasmic reticulum (ER) stress is a central actor in the physiopathology of insulin resistance (IR) in various tissues. The subsequent unfolded protein response (UPR) interacts with insulin signaling through inositol-requiring 1α (IRE1α) activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2aa8ad079ec0322a8ac2c3412291e6c
https://doi.org/10.1002/cbin.10542
https://doi.org/10.1002/cbin.10542
Autor:
Audrey Ginion, Louis Hue, Benoit Viollet, Elham Zarrinpashneh, Mark H. Rider, Christophe Beauloye, Bénédicte Demeulder, Luc Bertrand, Sandrine Horman, Jean-Louis Vanoverschelde
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1832:780-790
Eukaryotic elongation factor 2 (eEF-2) and mammalian target of rapamycin (mTOR)–p70 ribosomal protein S6 kinase (p70S6K) signaling pathways control protein synthesis and are inhibited during myocardial ischemia. Intracellular acidosis and AMP-activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1b2d2e92a4cd3c358e784ed08622dd
https://doi.org/10.1016/j.bbadis.2013.02.015
https://doi.org/10.1016/j.bbadis.2013.02.015
Autor:
Marc Francaux, Damien Naslain, Gilles Caty, Bénédicte Demeulder, Raphael Fortin, Louise Deldicque, Olivier Lutz
Publikováno v:
Nutrients, Vol. 8, no. 1, p. E47 [1-16] (2016)
Nutrients; Volume 8; Issue 1; Pages: 47
Nutrients, Vol 8, Iss 1, p 47 (2016)
Nutrients
Nutrients; Volume 8; Issue 1; Pages: 47
Nutrients, Vol 8, Iss 1, p 47 (2016)
Nutrients
This study was designed to better understand the molecular mechanisms involved in the anabolic resistance observed in elderly people. Nine young (22 ± 0.1 years) and 10 older (69 ± 1.7 years) volunteers performed a one-leg extension exercise consis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e209b93b07b772c3e91d940c6880597
https://hdl.handle.net/2078.1/172345
https://hdl.handle.net/2078.1/172345
Autor:
Hélène Gilson, Pascale Lause, Olivier Schakman, Jean-Paul Thissen, Stéphanie Kalista, Mario Pende, Luc Bertrand, Bénédicte Demeulder
Publikováno v:
Endocrinology; Vol 153
Myostatin inhibition by follistatin (FS) offers a new approach for muscle mass enhancement. The aim of the present study was to characterize the mediators responsible for the FS hypertrophic action on skeletal muscle in male mice. Because IGF-I and I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584672c6ad9a3589adb30333ab3fd1a9
Autor:
Raphael Fortin, Damien Naslain, Olivier Lutz, Bénédicte Demeulder, Marc Francaux, Gilles Caty
Publikováno v:
The FASEB Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9731f12f368a4454ecbf259413ab3146
https://doi.org/10.1096/fasebj.28.1_supplement.702.4
https://doi.org/10.1096/fasebj.28.1_supplement.702.4
Autor:
Christophe Beauloye, Sandrine Horman, Luc Bertrand, Audrey Ginion, Jean-Luc Balligand, Roselle Gélinas, Bénédicte Demeulder, Louis Hue, Jean-Louis Vanoverschelde, Johanna Hammond, Florence Mailleux
Publikováno v:
Archives of Cardiovascular Diseases Supplements. 7:190-191
Background We have previously shown that the AMPK specific activator, A769662, is able to block phenylephrine (PE)-induced hypertrophy without affecting the previously identified AMPK-related key regulators of cardiac hypertrophy, namely protein synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45953d60b47b7a6c19c79ab1dcf7bc23
https://doi.org/10.1016/s1878-6480(15)30161-0
https://doi.org/10.1016/s1878-6480(15)30161-0
Autor:
Louis Hue, Jean-Luc Balligand, Luc Bertrand, Bénédicte Demeulder, Cossette Sanchez Canedo, Jose R. Bayascas, Jean-Louis Vanoverschelde, Christophe Beauloye, Audrey Ginion, Dario R. Alessi
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 298(4)
Like insulin, leucine stimulates the mammalian target of rapamycin (mTOR)/p70 ribosomal S6 kinase (p70S6K) axis in various organs. Insulin proceeds via the canonical association of phosphatidylinositol 3-kinase (PI3K), phosphoinositide-dependent prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f6ee9c31641575bd78332764fa5fb6
https://pubmed.ncbi.nlm.nih.gov/20051528
https://pubmed.ncbi.nlm.nih.gov/20051528
Autor:
Audrey Ginion, Roselle Gélinas, Sandrine Horman, Christophe Beauloye, Johanna Hammond, Louis Hue, Jean-Luc Balligand, Bénédicte Demeulder, Florence Mailleux, Luc Bertrand, Jean-Louis Vanoverschelde
Publikováno v:
Archives of Cardiovascular Diseases Supplements. :57
BackgroundAMPK activators, like resveratrol or metformin, inhibit pathological cardiac hypertrophy. However, despite evidence for their anti-hypertrophic effect, it seems that this phenomenon is mainly circumstantial. Indeed, those agents induce a ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d680b22e9533a04bc1de2db2e221745