Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Béla M. Prágai"'
Autor:
Charles M. Rice, Béla M. Prágai, Mara Lippa, Sondra Schlesinger, Ilya Frolov, Eugene Agapov, Thomas A. Hoffman
Publikováno v:
Journal of Virology. 73:3854-3865
The natural life cycle of alphaviruses, a group of plus-strand RNA viruses, involves transmission to vertebrate hosts via mosquitoes. Chronic infections are established in mosquitoes (and usually in mosquito cell cultures), but infection of susceptib
Autor:
Henry V. Huang, Sergey A. Dryga, Charles M. Rice, Béla M. Prágai, Ilya Frolov, Thomas A. Hoffman, Sondra Schlesinger
Publikováno v:
Proceedings of the National Academy of Sciences. 93:11371-11377
Alphaviruses are positive-strand RNA viruses that can mediate efficient cytoplasmic gene expression in insect and vertebrate cells. Through recombinant DNA technology, the alphavirus RNA replication machinery has been engineered for high-level expres
Publikováno v:
Journal of Virology. 68:8147-8157
The hepatitis C virus H strain (HCV-H) polyprotein is cleaved to produce at least 10 distinct products, in the order of NH2-C-E1-E2-p7-NS2-NS3-NS4A-NS4B-NS5A-NS5B -COOH. An HCV-encoded serine proteinase activity in NS3 is required for cleavage at fou
Publikováno v:
Journal of Virology. 68:5063-5073
The hepatitis C virus (HCV) H strain polyprotein is cleaved to produce at least nine distinct products: NH2-C-E1-E2-NS2-NS3-NS4A-NS4B-NS5A-NS5B-CO OH. In this report, a series of C-terminal truncations and fusion with a human c-myc epitope tag allowe
Publikováno v:
Journal of Virology. 65:6714-6723
A heterologous system expressing functional Sindbis virus nonstructural proteins (nsPs) has several possible uses for studying Sindbis virus-specific RNA replication and transcription in vivo and in vitro. Of the many possible approaches, vaccinia vi
Autor:
Rudolf K. F. Beran, Béla M. Prágai, Brett D. Lindenbach, Charles M. Rice, Anna Marie Pyle, François Penin, Roland Montserret
Hepatitis C virus (HCV) nonstructural protein 4A (NS4A) is only 54 amino acids (aa) in length, yet it is a key regulator of the essential serine protease and RNA helicase activities of the NS3-4A complex, as well as a determinant of NS5A phosphorylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15a682f3de6357179e79d8faea55b1a
https://europepmc.org/articles/PMC1951449/
https://europepmc.org/articles/PMC1951449/
Autor:
Charles M. Rice, Béla M. Prágai, Sondra Schlesinger, Ilya Frolov, Brett D. Lindenbach, Eugene Agapov
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 95(22)
Infection of vertebrate cells with alphaviruses normally leads to prodigious expression of virus-encoded genes and a dramatic inhibition of host protein synthesis. Recombinant Sindbis viruses and replicons have been useful as vectors for high level f
Autor:
Béla M. Prágai, David Apirion
Publikováno v:
Journal of Molecular Biology. 154:465-484
Infection of the Escherichia coli RNA-processing mutant rne with the bacteriophage strain T4Δ27 (a deletion in the transfer RNA region that leaves intact only three of the ten final RNA molecules) results in a reduced accumulation of the three matur
Publikováno v:
Biochemical and Biophysical Research Communications. 106:768-778
The three enzymes, RNAase III, RNAase E and RNAase P participate in the processing of RNA precursors in Escherichia coli . In extracts which contain a mutated RNAase III or RNAase E under certain conditions RNAase P activity is not expressed while in
Autor:
David Apirion, Béla M. Prágai
Publikováno v:
Journal of Molecular Biology. 153:619-630
In order to assess the contribution of the processing enzyme RNAase III to the maturation of bacteriophage T4 transfer RNA, RNAase III + and RNAase III − strains were infected with T4 and the tRNAs produced were analyzed. Infection of the RNAase II