Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Béatrice Vayssière"'
Autor:
R Galien, Raphael Geney, Koen Kurt Smits, Béatrice Vayssière, Thierry Christophe, Reginald Brys, L. Lepescheux, Ellen van der Aar, Luc Nelles, Fabrice Ciesielski, Guy Van Lommen, Pierre Deprez, Luc Juliaan Corina Van Rompaey, Muriel Uhring, Stephen Robert Fletcher, Christel Jeanne Marie Menet, Philippe Clément-Lacroix, Javier Blanc, Nolwenn Jouannigot
Publikováno v:
Journal of Medicinal Chemistry. 57:9323-9342
Janus kinases (JAK1, JAK2, JAK3, and TYK2) are involved in the signaling of multiple cytokines important in cellular function. Blockade of the JAK-STAT pathway with a small molecule has been shown to provide therapeutic immunomodulation. Having ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9517bf576a1a79fdee93942c785e39bf
https://doi.org/10.1021/jm501262q
https://doi.org/10.1021/jm501262q
Autor:
Jean Feyen, L. Lepescheux, Thierry Christophe, Luc Juliaan Corina Van Rompaey, Luc Nelles, Reginald Brys, Steve De Vos, Nick Vandeghinste, Gerben van ’t Klooster, Ellen van der Aar, Bart Smets, Stephen Robert Fletcher, Philippe Clément-Lacroix, Béatrice Vayssière, R Galien, Katja Conrath, Christel Jeanne Marie Menet
Publikováno v:
The Journal of Immunology. 191:3568-3577
The JAKs receive continued interest as therapeutic targets for autoimmune, inflammatory, and oncological diseases. JAKs play critical roles in the development and biology of the hematopoietic system, as evidenced by mouse and human genetics. JAK1 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed129cea4d418b29aaf896dc9e7f5b99
https://doi.org/10.4049/jimmunol.1201348
https://doi.org/10.4049/jimmunol.1201348
Expression, purification and functional characterization of Wnt signaling co-receptors LRP5 and LRP6
Autor:
Helene Lebhar, Corinne Gillard, Patrick Mollat, Robert Touitou, Damien Fleury, Georges Rawadi, Béatrice Vayssière
Publikováno v:
Protein Expression and Purification. 70:39-47
Activation of the Wnt signaling cascade plays a pivotal role during development and in various disease states. Wnt signals are transduced by seven-transmembrane Frizzled (Fz) proteins and the single-transmembrane LDL-receptor-related proteins 5 or 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714b83aaeba260721f144b38bdf5d87e
https://doi.org/10.1016/j.pep.2009.08.012
https://doi.org/10.1016/j.pep.2009.08.012
Autor:
Béatrice Vayssière, Patrick Mollat, Christof Niehrs, Patrick Martin, Sergio Roman Roman, Philippe Pognonec, Isabelle Suc-Royer, Patrick Ammann, Frederic Morvan, Kim E. Boulukos, Georges Rawadi, Sonia Pinho, Philippe Clément-Lacroix, Roland Baron
Publikováno v:
Journal of Bone and Mineral Research. 21:934-945
Wnt/β-catenin signaling has been proven to play a central role in bone biology. Unexpectedly, the Wnt antagonist Dkk2 is required for terminal osteoblast differentiation and mineralized matrix formation. We show that Dkk1, unlike Dkk2, negatively re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c621c2169aeb7f6f875247874ae204fd
https://doi.org/10.1359/jbmr.060311
https://doi.org/10.1359/jbmr.060311
Autor:
Chi Faucheu, Sergio Roman-Roman, Robert Touitou, Eric Haÿ, Veronique Stiot, Isabelle Suc-Royer, Georges Rawadi, Béatrice Vayssière, Roland Baron
Publikováno v:
Journal of Biological Chemistry. 280:13616-13623
Low density lipoprotein receptor-related protein 5 (LRP5) has been identified as a Wnt co-receptor involved in the activation of the beta-catenin signaling pathway. To improve our understanding of the molecular mechanisms by which LRP5 triggers the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2efeb77ced695f2d34df0a1c6eab016
https://doi.org/10.1074/jbc.m411999200
https://doi.org/10.1074/jbc.m411999200
BMP-2 Controls Alkaline Phosphatase Expression and Osteoblast Mineralization by a Wnt Autocrine Loop
Publikováno v:
Journal of Bone and Mineral Research. 18:1842-1853
Wnt/β-catenin signaling has recently been suggested to be involved in bone biology. The precise role of this cascade in osteoblast differentiation was examined. We show that a Wnt autocrine loop mediates the induction of alkaline phosphatase and min
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dade1b4c6b2b9f797158336bcbbb0e2d
https://doi.org/10.1359/jbmr.2003.18.10.1842
https://doi.org/10.1359/jbmr.2003.18.10.1842
Autor:
Roland Baron, Eliane Mandine, Pierre Deprez, Véronique Jean-Baptiste, Dominique Lesuisse, Béatrice Vayssière, Didier Benard, Dominique Gofflo, Giulio Superti-Furga, Edoardo Sarubbi
Publikováno v:
Biochemical and Biophysical Research Communications. 298:185-192
The Src-SH2 domain has been determined to play a key role in many signaling pathways, especially in osteoclast-mediated bone resorption. Therefore, non-peptidic small molecules, mimicking the natural pYEEI peptide ligand, have been designed, to inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486011974f89264ccb5f1a700cb989ad
https://doi.org/10.1016/s0006-291x(02)02424-5
https://doi.org/10.1016/s0006-291x(02)02424-5
Autor:
Francisco Romero, Roland Berger, Béatrice Vayssière, Jacques Camonis, Corinne Leprince, Didier Cussac, Armand Tavitian
Publikováno v:
ResearcherID
Src homology 3 (SH3) domains are conserved modules which participate in protein interaction by recognizing proline-rich motifs on target molecules. To identify new SH3-containing proteins, we performed a two-hybrid screen with a proline-rich region o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda978c919e9af0c7451c175b8c78d81
https://doi.org/10.1074/jbc.272.24.15101
https://doi.org/10.1074/jbc.272.24.15101
Publikováno v:
Gastroenterology. 150:S379
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92c5ccc5c220ab59000e0389c6699dee
https://doi.org/10.1016/s0016-5085(16)31333-6
https://doi.org/10.1016/s0016-5085(16)31333-6
Autor:
Damien Fleury, Béatrice Vayssière, Robert Touitou, Georges Rawadi, Helene Lebhar, Corinne Gillard, Patrick Mollat
Publikováno v:
Protein expression and purification. 60(1)
Dickkopf-1 (Dkk1) protein is a secreted inhibitor of canonical Wnt signaling and modulates that pathway during embryonic development. It is also implicated in several diseases and hence Dkk1 is a potential target for therapeutic intervention. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8203e96c7f206ab22cf819749efcc70
https://pubmed.ncbi.nlm.nih.gov/18456511
https://pubmed.ncbi.nlm.nih.gov/18456511