Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Béatrice Plougastel"'
Autor:
Bijal A. Parikh, Michael D. Bern, Sytse J. Piersma, Liping Yang, Diana L. Beckman, Jennifer Poursine-Laurent, Béatrice Plougastel-Douglas, Wayne M. Yokoyama
Publikováno v:
Cell Reports, Vol 32, Iss 4, Pp 107969- (2020)
Summary: Major histocompatibility complex class I (MHC-I)-restricted immune responses are largely attributed to cytotoxic T lymphocytes (CTLs). However, natural killer (NK) cells, as predicted by the missing-self hypothesis, have opposing requirement
Externí odkaz:
https://doaj.org/article/afa279b4721442ef96a64b2fe1c7986a
Autor:
Wayne M. Yokoyama, Marco Colonna, Ryan W. Crump, Jill Schriewer, Ed Hembrador, Aaron S. Rapaport, Hanspeter Pircher, Jian Gao, Gaelle Le Friec, Béatrice Plougastel, R. Mark L. Buller, Yaming Wang, Susan Gilfillan, Marina Cella
Publikováno v:
Immunity. 43(6):1112-1124
CD8(+) T cells and NK cells protect from viral infections by killing virally infected cells and secreting interferon-γ. Several inhibitory receptors limit the magnitude and duration of these anti-viral responses. NKG2A, which is encoded by Klrc1, is
Publikováno v:
Nature Immunology. 4:801-807
The natural killer (NK) gene complex (NKC) encodes orphan lectin-like NK cell receptors that may explain uncharacterized NK cell specificities. Unlike other NKC-encoded receptors that recognize molecules with major histocompatibility complex (MHC) cl
Autor:
Béatrice Plougastel, Wayne M. Yokoyama
Publikováno v:
Nature Reviews Immunology. 3:304-316
There has been marked progress in our understanding of the role of natural killer (NK) cells in immune responses, mainly due to the identification of NK-cell receptors and their ligands. The genes encoding many NK-cell receptors are located in the NK
Publikováno v:
Immunogenetics. 53:592-598
The murine Nkrp1 gene family encodes three previously identified activation and inhibitory receptors expressed on natural killer (NK) cells. This family includes the gene for NKR-P1C (NK1.1), the most specific serologic marker on C57BL/6-derived NK c
Autor:
John Trowsdale, Béatrice Plougastel
Publikováno v:
Genomics. 49:193-199
The NKG2 family of genes (HGMW-approved symbol KLRC) contains at least four members (NKG2-A, -C, -E, and -F) which are localized to human chromosome 12p12.3-p13.2. This region, called the natural killer (NK) complex, encodes for lectin-like genes pre
Publikováno v:
EMBO journal, 16(20), 6087-6094. Wiley-Blackwell
Proteasomes are proteolytic complexes involved in non-lysosomal degradation which are localized in both the cytoplasm and the nucleus. The dynamics of proteasomes in living cells is unclear, as is their targeting to proteins destined for degradation.
Autor:
Pieter DeJong, P. Merel, Thomas Melot, Jessica Zucman, Béatrice Plougastel, M. Sanson, Khê Hoang-Xuan, Gilles Thomas, Chantal Desmaze, Alain Aurias, Olivier Delattre, Guy A. Rouleau
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 59:555-564
Publikováno v:
Genomics. 18:609-615
The EWS gene has been identified based on its location at the chromosome 22 breakpoint of the t(11;22)(q24;q12) translocation that characterizes Ewing sarcoma and related neuroectodermal tumors. The EWS gene spans about 40 kb of DNA and is encoded by
Autor:
Jessica Zucman, Guy A. Rouleau, Gilles Thomas, Martine Peter, Alain Aurias, Thomas Melot, Chantal Desmaze, Olivier Delattre, Isabelle Joubert, Pieter J. de Jong, Béatrice Plougastel
Publikováno v:
Genes, Chromosomes and Cancer. 5:271-277
Ewing's sarcoma (ES) and peripheral neuroepithelioma (PN) are related tumors, possibly of neural crest origin, which are cytogenetically characterized by the specific translocation t(11;22)(q24;q 12). The cos5 locus, previously identified in the vici