Regulation of skeletal muscle oxidative capacity and muscle mass by SIRT3.

Autor: Ligen Lin, Keyun Chen, Waed Abdel Khalek, Jack Lee Ward, Henry Yang, Béatrice Chabi, Chantal Wrutniak-Cabello, Qiang Tong

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e85636 (2014)

We have previously reported that the expression of mitochondrial deacetylase SIRT3 is high in the slow oxidative muscle and that the expression of muscle SIRT3 level is increased by dietary restriction or exercise training. To explore the function of

Externí odkaz: https://doaj.org/article/a07e0d10e53643fda8d1e0a15616b9e1

SIRT3, a mitochondrial NAD⁺-dependent deacetylase, is involved in the regulation of myoblast differentiation.

Autor: Waed Abdel Khalek, Fabienne Cortade, Vincent Ollendorff, Laure Lapasset, Lionel Tintignac, Béatrice Chabi, Chantal Wrutniak-Cabello

Publikováno v: PLoS ONE, Vol 9, Iss 12, p e114388 (2014)

Sirtuin 3 (SIRT3), one of the seven mammalian sirtuins, is a mitochondrial NAD+-dependent deacetylase known to control key metabolic pathways. SIRT3 deacetylases and activates a large number of mitochondrial enzymes involved in the respiratory chain,

Externí odkaz: https://doaj.org/article/f08bb3b5cf6d4cb58ca304cab8391558

Chicoric acid is an antioxidant molecule that stimulates AMP kinase pathway in L6 myotubes and extends lifespan in Caenorhabditis elegans.

Autor: Audrey Schlernitzauer, Catherine Oiry, Raphael Hamad, Simon Galas, Fabienne Cortade, Béatrice Chabi, François Casas, Laurence Pessemesse, Gilles Fouret, Christine Feillet-Coudray, Gérard Cros, Gérard Cabello, Richard Magous, Chantal Wrutniak-Cabello

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e78788 (2013)

Chicoric acid (CA) is a caffeoyl derivative previously described as having potential anti-diabetic properties. As similarities in cellular mechanism similarities between diabetes and aging have been shown, we explored on L6 myotubes the effect of CA

Externí odkaz: https://doaj.org/article/9fbe13c8d1bc4caab328b1b67292dbbb

Characterization of mitochondrial respiratory complexes involved in the regulation of myoblast differentiation

Autor: Fabienne Cortade, Béatrice Chabi, Hanane Hennani, Chantal Wrutniak-Cabello

Publikováno v: Cell Biology International
Cell Biology International, Wiley, 2021, ⟨10.1002/cbin.11602⟩

International audience; During myoblast differentiation, mitochondria undergo numerous changes that are necessary for the progression of the myogenic program. Notably, we previously showed that alteration in mitochondrial activity was able to control

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a948967b10ddd57cd19eb74051afb479
https://hal.inrae.fr/hal-03201669

Generating reference values on mitochondrial respiration in permeabilized muscle fibers

Autor: Béatrice, Chabi, Ost, M, Gama-Perez, P, Dahdah, N, Lemieux, H, Holody, CD, Carpenter, RG, Tepp, K, Puurand, M, Kaambre, T, Dubouchaud, H, Cortade, F, Pesta, D, Calabria, E, Casado, M, Fernandez-Ortiz, M, Acuña-Castroviejo, D, Villena, JA, Grefte, S, Keijer, J, O'Brien, K, Sowton, A, Murray, AJ, Campbell, MD, Marcinek, DJ, Wüst, R, Dayanidhi, S, Gnaiger, E, Doerrier, C, Garcia-Roves PM, PM, Nollet, E

Publikováno v: MitoFit Preprint Archives
MiP2019/MitoEAGLE-14th Conference on Mitochondrial Physiology: Mitochondrial function: changes during life cycle and in noncommunicable diseases
MiP2019/MitoEAGLE-14th Conference on Mitochondrial Physiology: Mitochondrial function: changes during life cycle and in noncommunicable diseases, Mitochondrial Physiology Society, Oct 2019, Belgrade, Serbia. 3p., ⟨10.26124/mitofit:ea19.MitoEAGLE.0001⟩

Permeabilized muscle fibers (pfi) are widely used to assess mitochondrial (mt) respiratory function in skeletal muscle of various models in different physiological and pathological conditions. Facing the numerous data available for mt-respiration fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff6ea783625e7757d7426003342ca55
https://hal.inrae.fr/hal-02941367/document