Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Béatrice Assouline-Thomas"'
Autor:
Maria Petropavlovskaia, Beatrice Assouline-Thomas, Jessica Cuerquis, Jing Zhao, Shaun Violette-Deslauriers, Eni Nano, Nicoletta Eliopoulos, Lawrence Rosenberg
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35372- (2024)
Mesenchymal stem/stromal cells (MSCs) are emerging as a new therapy for diabetes. Here we investigate the properties of MSCs engineered to express Islet Neogenesis Associated Protein (INGAP) previously shown to reverse diabetes in animal models and e
Externí odkaz:
https://doaj.org/article/f41f8cdf79f647ae8031aed30ac59381
Autor:
Béatrice Assouline-Thomas, Maria Petropavlovskaia, Jonathan Zhu, Lawrence Rosenberg, Julia Makhlin, Jieping Ding, Jamal Daoud, Mandana Moosavi
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 303:E917-E927
Islet neogenesis-associated protein (INGAP) was discovered in the partially duct-obstructed hamster pancreas as a factor inducing formation of new duct-associated islets. A bioactive portion of INGAP, INGAP104–118peptide (INGAP-P), has been shown t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c875b66197d019521f63a48462e382f1
https://doi.org/10.1152/ajpendo.00670.2011
https://doi.org/10.1152/ajpendo.00670.2011
Publikováno v:
Journal of Endocrinology. 211:231-239
Given the inherent therapeutic potential of the morphogenetic plasticity of adult human islets, the identification of factors controlling their cellular differentiation is of interest. The epidermal growth factor (EGF) family has been identified prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8989a4c13212ece80d346c50ecaac0db
https://doi.org/10.1530/joe-11-0213
https://doi.org/10.1530/joe-11-0213
Autor:
Béatrice Assouline-Thomas, David V. McLeod, Julia Makhlin, Jieping Ding, Maria Petropavlovskaia, Amélie Pilotte, Stephen C. Hanley, Bernard Massie, Lawrence Rosenberg
Publikováno v:
Protein Expression and Purification. 69:1-8
Islet Neogenesis Associated Protein (INGAP) is implicated in pancreatic islet neogenesis. INGAP peptide, a pentadecapeptide comprising amino acids 104–118, reverses diabetes in rodents and improves glucose homeostasis in patients with diabetes. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5807b7bfa1cb886189e8d287a6e587a3
https://doi.org/10.1016/j.pep.2009.07.009
https://doi.org/10.1016/j.pep.2009.07.009
Autor:
Lawrence Rosenberg, Maria Petropavlovskaia, Daniel Ellis, Julia Makhlin, Jieping Ding, Béatrice Assouline-Thomas
Publikováno v:
Differentiation; research in biological diversity. 90(4-5)
Regeneration of β-cells in diabetic patients is an important goal of diabetes research. Islet Neogenesis Associated Protein (INGAP) was discovered in the partially duct-obstructed hamster pancreas. Its bioactive fragment, pentadecapeptide 104-118 (I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4012d08de824c79bbfdc2023e4e39b95
https://pubmed.ncbi.nlm.nih.gov/26558987
https://pubmed.ncbi.nlm.nih.gov/26558987
Autor:
Emily Austin, Béatrice Assouline-Thomas, Maria Petropavlovskaia, Mandana Moosavi, Jason Blaichman, Stephen C. Hanley, Jordanna Kapeluto, Lawrence Rosenberg
Publikováno v:
Endocrinology. 151(4)
Studies of long-standing type 2 diabetes (T2D) report a deficit in beta-cell mass due to increased apoptosis, whereas neogenesis and replication are unaffected. It is unclear whether these changes are a cause or a consequence of T2D. Moreover, wherea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784db7c8586dded9d4a1057699cb16cb
https://pubmed.ncbi.nlm.nih.gov/20176718
https://pubmed.ncbi.nlm.nih.gov/20176718
Publikováno v:
Canadian Journal of Diabetes. 32:339
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46bf9db91b94598029e52631d758bef5
https://doi.org/10.1016/s1499-2671(08)24158-4
https://doi.org/10.1016/s1499-2671(08)24158-4