Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bärbel Friedrichs"'
Autor:
Bärbel Friedrichs, Simone Rehg, Kay-Martin Hanschmann, Volker Öppling, Isabelle Bekeredjian-Ding
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Lot release testing of diphtheria, tetanus and acellular pertussis vaccines traditionally relied on in vivo protection models involving challenge of laboratory animals with toxins. Meanwhile, many labs have switched to serological testing of
Externí odkaz:
https://doaj.org/article/3801193e6be9480c87adcbc8df0299fe
Publikováno v:
Toxicology in Vitro. 28:1249-1258
In vitro treatment of human peripheral blood neutrophils from smokers and non-smokers with an aqueous cigarette smoke (CS) extract resulted in a concentration-dependent increase in surface expression of CD11b and CD66b and a corresponding decrease of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f500bde9539d42e03b23eaff0b45cfc5
https://doi.org/10.1016/j.tiv.2014.06.007
https://doi.org/10.1016/j.tiv.2014.06.007
Autor:
Stephan Gebel, Haiyan Xu, Thomas Müller, Bärbel Friedrichs, J L Pype, Svenja Diehl, Jutta Schüller, H. Weiler, Masayuki Yamamoto, Keiko Taguchi
Publikováno v:
Toxicological Sciences. 115:238-252
Cigarette smoke (CS) imposes a strong oxidative burden on exposed tissues resulting in a severely disturbed oxidant/antioxidant balance, which in the context of chronic exposure is assumed to be a key contributor to CS-related diseases. Because of it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c260bf1f87761dda247c950d96f47557
https://doi.org/10.1093/toxsci/kfq039
https://doi.org/10.1093/toxsci/kfq039
Publikováno v:
Experimental Lung Research. 32:151-179
Female Sprague-Dawley rats were exposed to mainstream smoke from standard reference cigarettes and a nontobacco cellulose cigarette for 35 days. Whole smoke and smoke fractions were investigated. Lung inflammation was evaluated by differentiation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5b8e6a01a589c15d704bb32b9e2350
https://doi.org/10.1080/01902140600817457
https://doi.org/10.1080/01902140600817457
Autor:
Lutz Heinevetter, Cordula Müller, Bärbel Friedrichs, Michal Toborek, Regina Brigelius-Flohé, Bernhard Hennig
Publikováno v:
BioFactors. 9:61-72
Expression of cellular adhesion molecules (CAMs) at endothelial surfaces represents a physiological response to vascular damage and mediates the initiation of inflammation and possibly of atherogenesis. The cytokines TNF alpha and IL-1 are potent ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75598c97de18da447a0035cebb093c2c
https://doi.org/10.1002/biof.5520090108
https://doi.org/10.1002/biof.5520090108
Autor:
Stefanie Maurer, Bärbel Friedrichs, Rüdiger Streicher, Manfred Schultz, Regina Brigelius-Flohé
Publikováno v:
Biochemical Journal. 328:199-203
Oxygen radicals are commonly accepted mediators in the tumour necrosis factor-mediated nuclear factor κB (NFκB) signalling cascade, but evidence for their role during interleukin-1 (IL-1) signalling is lacking. To test the involvement of hydroperox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df4a73388768f563044d3591f7255e5
https://doi.org/10.1042/bj3280199
https://doi.org/10.1042/bj3280199
Autor:
Birgit Gerstenberg, Kenneth F. Podraza, Peter Schnell, Kris Meurrens, Detlef Veltel, Regina Stabbert, Christopher R. E. Coggins, Bärbel Friedrichs, Willy Gomm, Piter Terpstra, Susanne Weber, George J Patskan
Publikováno v:
Inhalation toxicology. 20(7)
Toxicological comparisons were made of three commercial cigarettes, namely Marlboro full flavor, Marlboro Lights, and Marlboro Ultra Lights, with the 1R4F reference cigarette. The main comparison was a 90-d inhalation study with mainstream smoke at 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc39df22fd3bd3420130cc2c176badd
https://pubmed.ncbi.nlm.nih.gov/18464057
https://pubmed.ncbi.nlm.nih.gov/18464057
Publikováno v:
Biological chemistry. 383(3-4)
Dietary hydroperoxides are being discussed as potential health hazards contributing to oxidative stress-related diseases. However, how food-born hydroperoxides could exert systemic effects remains elusive in view of the limited chances to be absorbed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e71d633fdae91038bab70d4a43b3e1a
https://pubmed.ncbi.nlm.nih.gov/12033453
https://pubmed.ncbi.nlm.nih.gov/12033453
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 18(12)
Abstract —The expression of endothelial-leukocyte adhesion molecules has been postulated to be regulated by redox-sensitive events. Tumor necrosis factor-α (TNF-α)– and interleukin-1 (IL-1)–induced E-selectin expression was analyzed after pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a86cdb6f1d5f2bb212a13ebba1b83e
https://pubmed.ncbi.nlm.nih.gov/9848873
https://pubmed.ncbi.nlm.nih.gov/9848873