Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Bärbel, Camara"'
Autor:
Dennis Das Gupta, Christoph Paul, Nadine Samel, Maria Bieringer, Daniel Staudenraus, Federico Marini, Hartmann Raifer, Lisa Menke, Lea Hansal, Bärbel Camara, Edith Roth, Patrick Daum, Michael Wanzel, Marco Mernberger, Andrea Nist, Uta-Maria Bauer, Frederik Helmprobst, Malte Buchholz, Katrin Roth, Lorenz Bastian, Alina M Hartmann, Claudia Baldus, Koichi Ikuta, Andreas Neubauer, Andreas Burchert, Hans-Martin Jäck, Matthias Klein, Tobias Bopp, Thorsten Stiewe, Axel Pagenstecher, Michael Lohoff
The processes leading from disturbed B cell development to adult B cell progenitor acute lymphoblastic leukemia (BCP-ALL) are poorly understood. Here, we describe Irf4−/− mice as prone to developing BCP-ALL with age. Irf4−/− preB-I cells exhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::019b2ff723d80862b81ffa903579885c
https://doi.org/10.1101/2022.02.16.480573
https://doi.org/10.1101/2022.02.16.480573
Autor:
Addi J. Romero-Olmedo, Axel Ronald Schulz, Svenja Hochstätter, Dennis Das Gupta, Heike Hirseland, Daniel Staudenraus, Bärbel Camara, Kirsten Volland, Véronique Hefter, Siddhesh Sapre, Verena Krähling, Helena Müller-Kräuter, Henrik E. Mei, Christian Keller, Michael Lohoff
A third mRNA-based “booster” vaccination is the favored strategy to maintain protection against SARS-CoV-2 infection. Yet, significant waning of specific immunity within six months after 2nd vaccination, along with higher incidence of breakthroug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d8160cd519cec4fc425887a79c9d7b0
https://doi.org/10.1101/2022.02.10.22270733
https://doi.org/10.1101/2022.02.10.22270733
Autor:
Addi J, Romero-Olmedo, Axel Ronald, Schulz, Svenja, Hochstätter, Dennis Das, Gupta, Heike, Hirseland, Daniel, Staudenraus, Bärbel, Camara, Kirsten, Volland, Véronique, Hefter, Siddhesh, Sapre, Verena, Krähling, Helena, Müller-Kräuter, Ho-Ryun, Chung, Henrik E, Mei, Christian, Keller, Michael, Lohoff
Publikováno v:
The Lancet Infectious Diseases. 22:588-589
Autor:
Daniel Staudenraus, Siddhesh Sapre, Iiris Virta, Heike Hirseland, Dennis DasGupta, Axel Schulz, Addi Romero Olmedo, Carina Münch, Svenja Hochstäter, Christian Keller, Bärbel Camara, Michael Lohoff, Henrik E. Mei, Véronique Hefter
Herein, we compared SARS-CoV-2-specific antibody and T-cell responses to two doses of BNT162b2 mRNA in 51 vaccinees > 80 years old and 46 (20–53 years old) controls. The responses of the elderly were much lower and 10% non-responders were identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea26beed0e6f28a9e4efcc7dca41e0b5
https://doi.org/10.21203/rs.3.rs-900790/v1
https://doi.org/10.21203/rs.3.rs-900790/v1
Autor:
Addi J. Romero-Olmedo, Axel Ronald Schulz, Svenja Hochstätter, Dennis Das Gupta, Iiris Virta, Heike Hirseland, Daniel Staudenraus, Bärbel Camara, Carina Münch, Véronique Hefter, Siddhesh Sapre, Verena Krähling, Helena Müller-Kräuter, Marek Widera, Henrik E. Mei, Christian Keller, Michael Lohoff
Publikováno v:
Nature microbiology
Here we compared SARS-CoV-2-specific antibody and T-cell responses between older adults (80 years old, n = 51) and a younger control group (20-53 years old, n = 46) after receiving two doses of BNT162b2. We found that responses in older adults were g
Autor:
Frederik Helmprobst, Hans-Martin Jäck, Andreas Neubauer, Maria Bieringer, Thorsten Stiewe, Marco Mernberger, Christoph Paul, Lisa Menke, Uta-Maria Bauer, Dennis Das Gupta, Nadine Bollig, Axel Pagenstecher, Federico Marini, Michael Wanzel, Andreas Burchert, Andrea Nist, Hartmann Raifer, Daniel Staudenraus, Matthias Klein, Michael Lohoff, Edith Roth, Bärbel Camara, Malte Buchholz, Patrick Daum, Tobias Bopp
How disturbances of B cell development provoke adult B acute lymphoblastic leukemia (B-ALL) remains poorly understood. Here we describe Irf4–/– mice as prone to developing B-ALL with age. Irf4–/– pro/preB cells exhibited impaired differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bafe58b8d57b37c741a4b4717fe64ab7
https://doi.org/10.21203/rs.3.rs-271184/v1
https://doi.org/10.21203/rs.3.rs-271184/v1
Autor:
Elfadil Abass, Nadine Bollig, Katharina Reinhard, Bärbel Camara, Durria Mansour, Alexander Visekruna, Michael Lohoff, Ulrich Steinhoff
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 7, p e2322 (2013)
BACKGROUND: For effective control of visceral leishmaniasis (VL) in East Africa, new rapid diagnostic tests are required to replace current tests with low sensitivity. The aim of this study is to improve diagnosis of VL in East Africa by testing a ne
Externí odkaz:
https://doaj.org/article/a7a17382d93d49ae9e9551d2a0d1fc1b
Autor:
Thorsten B. Feyerabend, Nadine Bollig, Michael Lohoff, Thea Zapf, Hans Reimer Rodewald, Christoph Paul, Claudia Trier, Svenja Wolff, Hartmann Raifer, Bärbel Camara, Ulrike Schleicher
Publikováno v:
European Journal of Immunology. 46:114-121
The genus leishmania comprises different protozoan parasites which are causative agents of muco-cutaneous and systemic, potentially lethal diseases. After infection with the species Leishmania major, resistant mice expand Th1 cells which stimulate ma
Autor:
Anne Brüstle, Michael Lohoff, Alekya Porapu, Hartmann Raifer, Bärbel Camara, Chol Ho Kang, Maria Bieringer, Daniel Staudenraus, Enno Hartmann, Olaf Pinkenburg, Elfadil Abass, Lisa Menke
Publikováno v:
European journal of immunology. 49(5)
We found that deletion of the final 30 amino acids of transcription factor IRF4's (interferon-regulatory factor) C-terminus creates hyperactive IRF4. When introduced into IRF4-deficient CD4+ or CD8+ T cells, more type 17 differentiation was found com
Autor:
Karsten Hiller, Anne Brüstle, Momoe Itsumi, Vasilis Vasiliou, Isaac S. Harris, Dirk Brenner, Tak W. Mak, Christian Jäger, Carsten Bindslev-Jensen, Maureen A. Cox, Catherine Dostert, Carole Binsfeld, Ying Chen, Philipp A. Lang, Michael Lohoff, Bärbel Camara, Yannic Nonnenmacher, Olaf Pinkenburg, Chiara Gorrini, Zhenyue Hao, Melanie Grusdat, Markus Ollert, Gordon S. Duncan
Publikováno v:
Mak, T W, Grusdat, M, Duncan, G S, Dostert, C, Nonnenmacher, Y, Cox, M, Binsfeld, C, Hao, Z, Brüstle, A, Itsumi, M, Jäger, C, Chen, Y, Pinkenburg, O, Camara, B, Ollert, M, Bindslev-Jensen, C, Vasiliou, V, Gorrini, C, Lang, P A, Lohoff, M, Harris, I S, Hiller, K & Brenner, D 2017, ' Glutathione Primes T Cell Metabolism for Inflammation ', Immunity, vol. 46, no. 4, pp. 675-689 . https://doi.org/10.1016/j.immuni.2017.03.019
Activated T cells produce reactive oxygen species (ROS), which trigger the antioxidative glutathione (GSH) response necessary to buffer rising ROS and prevent cellular damage. We report that GSH is essential for T cell effector functions through its