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Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination

Autor: De La Fuente, Alerie Guzman, Lange, Simona, Silva, Maria Elena, Gonzalez, Ginez A., Tempfer, Herbert, van Wijngaarden, Peter, Zhao, Chao, Di Canio, Ludovica, Trost, Andrea, Bieler, Lara, Zaunmair, Pia, Rotheneichner, Peter, O’Sullivan, Anna, Couillard-Despres, Sebastien, Errea, Oihana, Mäe, Maarja A., Andrae, Johanna, He, Liqun, Keller, Annika, Bátiz, Luis F., Betsholtz, Christer, Aigner, Ludwig, Franklin, Robin J.M., Rivera, Francisco J.

Publikováno v: De La Fuente, A G, Lange, S, Silva, M E, Gonzalez, G A, Tempfer, H, van Wijngaarden, P, Zhao, C, Di Canio, L, Trost, A, Bieler, L, Zaunmair, P, Rotheneichner, P, O'Sullivan, A, Couillard-Despres, S, Errea, O, Mäe, M A, Andrae, J, He, L, Keller, A, Bátiz, L F, Betsholtz, C, Aigner, L, Franklin, R J M & Rivera, F J 2017, ' Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination ', Cell Reports, vol. 20, no. 8, pp. 1755-1764 . https://doi.org/10.1016/j.celrep.2017.08.007
Cell Reports, Vol 20, Iss 8, Pp 1755-1764 (2017)
Cell Reports

Summary The role of the neurovascular niche in CNS myelin regeneration is incompletely understood. Here, we show that, upon demyelination, CNS-resident pericytes (PCs) proliferate, and parenchymal non-vessel-associated PC-like cells (PLCs) rapidly de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3e8cc323b0fe2407e2a5a303ef6fe219
https://pure.qub.ac.uk/en/publications/pericytes-stimulate-oligodendrocyte-progenitor-cell-differentiation-during-cns-remyelination(c397b1f7-39e4-4045-be9f-f369606da79c).html

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Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells

Autor: Silva, Maria Elena, Lange, Simona, Hinrichsen, Bryan, Philp, Amber R, Reyes, Carolina R, Halabi, Diego, Mansilla, Josselyne B, Rotheneichner, Peter, Guzman De La Fuente, Alerie, Couillard-Despres, Sebastien, Bátiz, Luis F, Franklin, Robin JM, Aigner, Ludwig, Rivera, Francisco J

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Upon demyelination, oligodendrocyte progenitor cells (OPCs) are activated and they proliferate, migrate and differentiate into myelin-producing olig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c5c1c680117b34a30cc27296bde7ff08

Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination

Autor: Luis Federico Bátiz, Sebastien Couillard-Despres, Eleni Priglinger, Patrick Küry, Andreas Traweger, Maria Elena Silva, Robin J.M. Franklin, Richard Greil, Francisco J. Rivera, Chao Zhao, Ludwig Aigner, Martina Feichtner, Roman Wodnar, Ginez A. Gonzalez, Anna O’Sullivan, Alerie Guzman de la Fuente, Simona Lange, Janusz J. Jadasz, Herbert Tempfer, Oihana Errea, Pasquale Romanelli, Gabriele Brachtl

Publikováno v: Rivera, F J, de la Fuente, A G, Zhao, C, Silva, M E, Gonzalez, G A, Wodnar, R, Feichtner, M, Lange, S, Errea, O, Priglinger, E, O'Sullivan, A, Romanelli, P, Jadasz, J J, Brachtl, G, Greil, R, Tempfer, H, Traweger, A, Bátiz, L F, Küry, P, Couillard-Despres, S, Franklin, R J M & Aigner, L 2019, ' Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination ', Glia, vol. 67, no. 8, pp. 1510-1525 . https://doi.org/10.1002/glia.23624
Glia

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) that leads to severe neurological deficits. Due to their immunomodulatory and neuroprotective activities and their ability to promote the generation of oligodendro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da7ab908c51e8e18bcbbff3e41f294b8
https://pure.qub.ac.uk/en/publications/aging-restricts-the-ability-of-mesenchymal-stem-cells-to-promote-the-generation-of-oligodendrocytes-during-remyelination(3d9b3b3e-2219-4dfb-9cf7-f0e863ea11df).html