Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Bárbara de A. Abrahim-Vieira"'
1
Akademický článek
Computational Studies of Benzoxazinone Derivatives as Antiviral Agents against Herpes Virus Type 1 Protease
Autor: Juliana F. R. Mello, Nathália C. Botelho, Alessandra M. T. Souza, Riethe Oliveira, Monique A. Brito, Bárbara de A. Abrahim-Vieira, Ana Carolina R. Sodero, Helena C. Castro, Lucio M. Cabral, Leonardo A. Miceli, Carlos R. Rodrigues
Publikováno v: Molecules, Vol 20, Iss 6, Pp 10689-10704 (2015)
Herpes simplex virus infections have been described in the medical literature for centuries, yet the the drugs available nowadays for therapy are largely ineffective and low oral bioavailability plays an important role on the inefficacy of the treatm
Externí odkaz: https://doaj.org/article/4c44b936310b4d6fb14b26f34c18c6d2
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2
Akademický článek
In Silico Analyses of a Promising Drug Candidate for the Treatment of Amyotrophic Lateral Sclerosis Targeting Superoxide Dismutase I Protein
Autor: Gabriel Rodrigues Coutinho Pereira, Bárbara de Azevedo Abrahim-Vieira, Joelma Freire de Mesquita
Publikováno v: Pharmaceutics, Vol 15, Iss 4, p 1095 (2023)
Amyotrophic lateral sclerosis (ALS) is the most prevalent motor neuron disorder in adults, which is associated with a highly disabling condition. To date, ALS remains incurable, and the only drugs approved by the FDA for its treatment confer a limite
Externí odkaz: https://doaj.org/article/466883845c254e3ea8187d5ffb871368
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3
Akademický článek
Comprehensive in silico analysis and molecular dynamics of the superoxide dismutase 1 (SOD1) variants related to amyotrophic lateral sclerosis.
Autor: Gabriel Rodrigues Coutinho Pereira, Bárbara de Azevedo Abrahim Vieira, Joelma Freire De Mesquita
Publikováno v: PLoS ONE, Vol 16, Iss 2, p e0247841 (2021)
Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disorder, with a significant social and economic burden. ALS remains incurable, and the only drugs approved for its treatments confers a survival benefit of a few months for the pa
Externí odkaz: https://doaj.org/article/acc89258ed00417d93f668124110e8fa
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4
In silico analyses of acetylcholinesterase (AChE) and its genetic variants in interaction with the anti‐Alzheimer drug Rivastigmine
Autor: Gabriel Rodrigues Coutinho, Pereira, Lucas Machado, Gonçalves, Bárbara de Azevedo, Abrahim-Vieira, Joelma Freire, De Mesquita
Publikováno v: Journal of Cellular Biochemistry. 123:1259-1277
Alzheimer's disease (AD) is the leading cause of dementia worldwide. Despite causing great social and economic impact, there is currently no cure for AD. The most effective therapy to manage AD symptoms is based on acetylcholinesterase inhibitors (AC
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f178aa850381f78c9cf7466d553d96c
https://doi.org/10.1002/jcb.30277
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5
Akademický článek
Antimycobacterial and Anti-Inflammatory Activities of Substituted Chalcones Focusing on an Anti-Tuberculosis Dual Treatment Approach
Autor: Thatiana Lopes Biá Ventura, Sanderson Dias Calixto, Bárbara de Azevedo Abrahim-Vieira, Alessandra Mendonça Teles de Souza, Marcos Vinícius Palmeira Mello, Carlos Rangel Rodrigues, Leandro Soter de Mariz e Miranda, Rodrigo Octavio Mendonça Alves de Souza, Ivana Correa Ramos Leal, Elena B. Lasunskaia, Michelle Frazão Muzitano
Publikováno v: Molecules, Vol 20, Iss 5, Pp 8072-8093 (2015)
Tuberculosis (TB) remains a serious public health problem aggravated by the emergence of M. tuberculosis (Mtb) strains resistant to multiple drugs (MDR). Delay in TB treatment, common in the MDR-TB cases, can lead to deleterious life-threatening infl
Externí odkaz: https://doaj.org/article/8a02e9dc9bc44a93a3b5e8c3e65fc20b
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7
Alternative Methods for Pulmonary-Administered Drugs Metabolism: a Breath of Change
Autor: Lucio Mendes Cabral, Érika Yoko Suzuki, Alice Simon, Thaisa Francielle Souza Domingos, Bárbara de Azevedo Abrahim Vieira, Alessandra Mendonça Teles de Souza, Carlos Rangel Rodrigues, Valeria Pereira de Sousa, Flávia Almada do Carmo
Publikováno v: Mini reviews in medicinal chemistry.
Abstract: Prediction of pulmonary metabolites following inhalation of a locally acting pulmonary drug is essential to the successful development of novel inhaled medicines. The lungs present metabolic enzymes, therefore they influence drug disposal a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c763d90b0353f1edb4b1d30f9e3ae79f
https://pubmed.ncbi.nlm.nih.gov/35726420
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8
Trehalose synthesis inhibitor: A molecular in silico drug design
Autor: Lucas Machado Gonçalves, Eduardo T. V. Trevisol, Joelma Freire De Mesquita, Bárbara de Azevedo Abrahim Vieira
Publikováno v: Journal of Cellular Biochemistry. 121:1114-1125
Infectious diseases are serious public health problems, affecting a large portion of the world's population. A molecule that plays a key role in pathogenic organisms is trehalose and recently has been an interest in the metabolism of this molecule fo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e998388d1178de7fe5fe024adfe2cfe4
https://doi.org/10.1002/jcb.29347
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9
Comprehensive in silico analysis and molecular dynamics of the superoxide dismutase 1 (SOD1) variants related to amyotrophic lateral sclerosis
Autor: Joelma Freire De Mesquita, Gabriel Rodrigues Coutinho Pereira, Bárbara de Azevedo Abrahim Vieira
Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0247841 (2021)
Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disorder, with a significant social and economic burden. ALS remains incurable, and the only drugs approved for its treatments confers a survival benefit of a few months for the pa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84998c5317bb36a659806496dff704c5
http://europepmc.org/articles/PMC7906464
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10
Brazilian stingless bee propolis and geopropolis: promising sources of biologically active compounds
Autor: Flávia Conde Lavinas, Gabriel B.L. Sá, Igor A. Rodrigues, Carla da Silva Carneiro, Thaisa Francielle Souza Domingos, Alane Beatriz Vermelho, Ellis Helena B.C. Macedo, Jefferson Rocha de A. Silva, Mariana M. B. Azevedo, Ana Claudia F. Amaral, Bárbara de Azevedo Abrahim Vieira
Publikováno v: Revista Brasileira de Farmacognosia, Volume: 29, Issue: 3, Pages: 389-399, Published: 26 AUG 2019
Revista Brasileira de Farmacognosia, Vol 29, Iss 3, Pp 389-399 (2019)
Revista Brasileira de Farmacognosia v.29 n.3 2019
Revista Brasileira de Farmacognosia
Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
Stingless bee products such as honey, pollen, propolis, and geopropolis have been used for centuries in traditional medicine for the treatment of several illnesses. Investigation of the biological activity of stingless bee products, especially propol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a49ff60de07d934f14eab85346b57b
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2019000300389&lng=en&tlng=en
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