Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Bárbara Lisboa Nogueira"'
Autor:
Rahyssa Rodrigues Sales, Bárbara Lisboa Nogueira, Jéssica Abdo Gonçalves Tosatti, Karina Braga Gomes, Marcelo Rizzatti Luizon
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Hydroxyurea has long been used for the treatment of sickle cell anemia (SCA), and its clinical effectiveness is related to the induction of fetal hemoglobin (HbF), a major modifier of SCA phenotypes. However, there is substantial variability in respo
Externí odkaz:
https://doaj.org/article/e0a5758e6370443da27d300af6210e33
Publikováno v:
Pharmacogenomics. 23:393-396
Autor:
Rahyssa Rodrigues Sales, Bárbara Lisboa Nogueira, André Rolim Belisário, Gabriela Faria, Fabiola Mendes, Marcos Borato Viana, Marcelo Rizzatti Luizon
Publikováno v:
Journal of human genetics. 67(12)
Single nucleotide polymorphisms (SNPs) of BCL11A gene and HBS1L-MYB intergenic region (named HMIP-2) affect both fetal hemoglobin (HbF) concentration and clinical outcomes in patients with sickle cell anemia (SCA). However, no previous study has exam