Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Bálint Szeder"'
Autor:
Virag Vas, Tamás Kovács, Szandra Körmendi, Andrea Bródy, Gyöngyi Kudlik, Bálint Szeder, Diána Mező, Dóra Kállai, Kitti Koprivanacz, Balázs L. Merő, Metta Dülk, József Tóvári, Péter Vajdovich, Ş. Neslihan Şenel, Ilknur Özcan, Zsuzsanna Helyes, Csaba Dobó-Nagy, László Buday
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract The main driver of osteoporosis is an imbalance between bone resorption and formation. The pathogenesis of osteoporosis has also been connected to genetic alterations in key osteogenic factors and dysfunction of bone marrow mesenchymal stem/
Externí odkaz:
https://doaj.org/article/96550bcba65a4bb08c3d5a75f608f18c
Autor:
Sabine Schuster, Beáta Biri-Kovács, Bálint Szeder, Viktor Farkas, László Buday, Zsuzsanna Szabó, Gábor Halmos, Gábor Mező
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 756-771 (2018)
Gonadotropin releasing hormone-III (GnRH-III), a native isoform of the human GnRH isolated from sea lamprey, specifically binds to GnRH receptors on cancer cells enabling its application as targeting moieties for anticancer drugs. Recently, we report
Externí odkaz:
https://doaj.org/article/6ec30774b7a549dc8709643a02cb7791
Tailoring Uptake Efficacy of HSV-1 gD Tailoring Uptake Efficacy of Hsv-1 GD Derived Carrier Peptides
Autor:
Szilvia Bősze, Ferenc Zsila, Beáta Biri-Kovács, Bálint Szeder, Zsuzsa Majer, Ferenc Hudecz, Katalin Uray
Publikováno v:
Biomolecules, Vol 10, Iss 5, p 721 (2020)
Regions of the Herpes simplex virus-1 (HSV-1) glycoprotein D (gD) were chosen to design carrier peptides based on the known tertiary structure of the virus entry receptor complexes. These complexes consist of the following: HSV-1 gD–nectin-1 and HS
Externí odkaz:
https://doaj.org/article/4f8f3ee791864a25bbdc823dcacfbc76
Publikováno v:
Biomolecules, Vol 10, Iss 2, p 183 (2020)
Human epidermal growth factor (HER2) is a transmembrane tyrosine kinase receptor that is frequently overexpressed in breast cancer. Its increased level prognoses a poor patient outcome and a high mortality rate. Despite the widening spectrum of thera
Externí odkaz:
https://doaj.org/article/dcb4382f48594121b1280f252560bb8c
Autor:
Bálint Szeder, Júlia Tárnoki-Zách, Dóra Lakatos, Virág Vas, Gyöngyi Kudlik, Balázs Merő, Kitti Koprivanacz, László Bányai, Lilla Hámori, Gergely Róna, András Czirók, András Füredi, László Buday
Publikováno v:
Cells, Vol 8, Iss 11, p 1343 (2019)
Epithelial to mesenchymal transition (EMT) is a multipurpose process involved in wound healing, development, and certain pathological processes, such as metastasis formation. The Tks4 scaffold protein has been implicated in cancer progression; howeve
Externí odkaz:
https://doaj.org/article/84376eed26f24ff19d7331d4d3cfb4a9
Autor:
Virag Vas, Tamás Háhner, Gyöngyi Kudlik, Dávid Ernszt, Krisztián Kvell, Dániel Kuti, Krisztina J. Kovács, József Tóvári, Mária Trexler, Balázs L. Merő, Bálint Szeder, Kitti Koprivanacz, László Buday
Publikováno v:
Cells, Vol 8, Iss 8, p 831 (2019)
Obesity and adipocyte malfunction are related to and arise as consequences of disturbances in signaling pathways. Tyrosine kinase substrate with four Src homology 3 domains (Tks4) is a scaffold protein that establishes a platform for signaling cascad
Externí odkaz:
https://doaj.org/article/2c46c956370d452e98b8fd27f1d13040
Autor:
Kata Horváti, Bernadett Pályi, Judit Henczkó, Gyula Balka, Eleonóra Szabó, Viktor Farkas, Beáta Biri-Kovács, Bálint Szeder, Kinga Fodor
Publikováno v:
Vaccines, Vol 7, Iss 3, p 101 (2019)
Epitopes from different proteins expressed by Mycobacterium tuberculosis (Rv1886c, Rv0341, Rv3873) were selected based on previously reported antigenic properties. Relatively short linear T-cell epitope peptides generally have unordered structure, li
Externí odkaz:
https://doaj.org/article/20908dc4378c4eaabf4478507f232286
Autor:
Sabine Schuster, Beáta Biri-Kovács, Bálint Szeder, László Buday, János Gardi, Zsuzsanna Szabó, Gábor Halmos, Gábor Mező
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 223 (2018)
Receptors for gonadotropin releasing hormone (GnRH) are highly expressed in various human cancers including breast, ovarian, endometrial, prostate and colorectal cancer. Ligands like human GnRH-I or the sea lamprey analogue GnRH-III represent a promi
Externí odkaz:
https://doaj.org/article/9cc728b212af47738f4f3d11d57d26ee
Autor:
Bálint Szeder, Françoise Illien, Zoltán Bánóczi, Ildikò Szabò, Beáta Biri-Kovács, Mo'ath Yousef, Sandrine Sagan
Publikováno v:
ChemistrySelect. 6:10111-10120
Autor:
Edit Pári, Szilvia Bősze, Zsuzsanna Németh, Bálint Szeder, Martin Krátký, Johanna Budai, Éva Kiss, László Cervenak, Jarmila Vinšová, Lilla Horváth, Bence Kovács, Márta L. Debreczeni, Előd Méhes, Zsuzsa Baranyai, Beáta Biri-Kovács, Ferenc Zsila
Publikováno v:
Journal of Medicinal Chemistry. 64:2982-3005
Most therapeutic agents used for treating brain malignancies face hindered transport through the blood-brain barrier (BBB) and poor tissue penetration. To overcome these problems, we developed peptide conjugates of conventional and experimental antic