Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Bálint Botz"'
Autor:
Ádám István Horváth, Kata Bölcskei, Nikolett Szentes, Éva Borbély, Valéria Tékus, Bálint Botz, Kitti Rusznák, Anett Futácsi, Boldizsár Czéh, Péter Mátyus, Zsuzsanna Helyes
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionMonoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxa
Externí odkaz:
https://doaj.org/article/7cfe2dd453ac46c1bfdceb5f12491f4b
Autor:
Balázs Sütő, Bálint Kolumbán, Éva Szabó, Sára Pásztor, Timea Németh, Teréz Bagoly, Bálint Botz, Erika Pintér, Zsuzsanna Helyes
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2154 (2023)
Somatostatin (SST) released from capsaicin-sensitive sensory nerves in response to stimulation exerts systemic anti-inflammatory, analgesic actions. Its elevation correlates with the extent of tissue injury. We measured plasma SST alterations during
Externí odkaz:
https://doaj.org/article/9904e718fe1d451caa6420bc54b9d8c4
Autor:
Noémi Bencze, Csaba Schvarcz, Gábor Kriszta, Lea Danics, Éva Szőke, Péter Balogh, Árpád Szállási, Péter Hamar, Zsuzsanna Helyes, Bálint Botz
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
There is growing interest in the role of nerve-driven mechanisms in tumorigenesis and tumor growth. Capsaicin-sensitive afferents have been previously shown to possess antitumoral and immune-regulatory properties, the mechanism of which is currently
Externí odkaz:
https://doaj.org/article/9b72cae0b74e46388cb4fbfdf0c45c8c
Autor:
Ádám Horváth, Éva Borbély, Kata Bölcskei, Nikolett Szentes, Tamás Kiss, Mátyás Belák, Tibor Rauch, Tibor Glant, Róza Zákány, Tamás Juhász, Edina Karanyicz, Ferenc Boldizsár, Zsuzsanna Helyes, Bálint Botz
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-12 (2018)
Abstract Objective The regulatory role of capsaicin-sensitive peptidergic sensory nerves has been shown in acute inflammation, but little is known about their involvement in T/B-cell driven autoimmune arthritis. This study integratively characterized
Externí odkaz:
https://doaj.org/article/caf56b2373f0485180b48577b7338bc7
Hemokinin-1 as a Mediator of Arthritis-Related Pain via Direct Activation of Primary Sensory Neurons
Autor:
Éva Borbély, Ágnes Hunyady, Krisztina Pohóczky, Maja Payrits, Bálint Botz, Attila Mócsai, Alexandra Berger, Éva Szőke, Zsuzsanna Helyes
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
The tachykinin hemokinin-1 (HK-1) is involved in immune cell development and inflammation, but little is known about its function in pain. It acts through the NK1 tachykinin receptor, but several effects are mediated by a yet unidentified target. The
Externí odkaz:
https://doaj.org/article/45778cb62aad4d08b8befeb81b6cb9d8
Autor:
Ádám Horváth, Bálint Botz, Tamás Kiss, Kata Csekő, Ibolya Kiss, Attila Felinger, Tamara Szabados, Éva Kenyeres, Péter Bencsik, Attila Mócsai, Péter Ferdinandy, Zsuzsanna Helyes
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Background: Rheumatoid arthritis (RA) is a chronic inflammatory joint disease hallmarked by irreversible damage of cartilage and bone. Matrix metalloproteinases (MMPs) involved in connective tissue remodeling play an important role in this process. N
Externí odkaz:
https://doaj.org/article/e337f10cb68246559515128348449a3e
Autor:
Réka Kugyelka, Lilla Prenek, Katalin Olasz, Zoltán Kohl, Bálint Botz, Tibor T. Glant, Timea Berki, Ferenc Boldizsár
Publikováno v:
Cells, Vol 8, Iss 5, p 504 (2019)
T cells play an essential role in the pathogenesis of both human rheumatoid arthritis (RA) and its murine models. A key molecule in T cell activation is ZAP-70, therefore we aimed to investigate the effects of partial ZAP-70 deficiency on the pathoge
Externí odkaz:
https://doaj.org/article/a74d5afd08354b84a3fbfba0bd44a795
Publikováno v:
Magyar Radiológia Online; 2024, Vol. 15 Issue 2, p1-8, 8p