Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Bálint, Sinkó"'
Autor:
Dóra Csicsák, Rita Szolláth, Szabina Kádár, Rita Ambrus, Csilla Bartos, Emese Balogh, István Antal, István Köteles, Petra Tőzsér, Vivien Bárdos, Péter Horváth, Enikő Borbás, Krisztina Takács-Novák, Bálint Sinkó, Gergely Völgyi
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 278 (2023)
Particle size reduction is a commonly used process to improve the solubility and the dissolution of drug formulations. The solubility of a drug in the gastrointestinal tract is a crucial parameter, because it can greatly influence the bioavailability
Externí odkaz:
https://doaj.org/article/818ecf934e124fd6b6c66a1e27eb8217
Autor:
Szabina Kádár, Dóra Csicsák, Petra Tőzsér, Attila Farkas, Tamás Pálla, Arash Mirzahosseini, Blanka Tóth, Gergő Tóth, Béla Fiser, Péter Horváth, János Madarász, Alex Avdeef, Krisztina Takács-Novák, Bálint Sinkó, Enikő Borbás, Gergely Völgyi
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1635 (2022)
Creating supersaturating drug delivery systems to overcome the poor aqueous solubility of active ingredients became a frequent choice for formulation scientists. Supersaturation as a solution phenomenon is, however, still challenging to understand, a
Externí odkaz:
https://doaj.org/article/1622635b265949a3bd393635b8beea63
Autor:
Petra Tőzsér, Luca L. Kovács, Szabina Kádár, Dóra Csicsák, Péter Sóti, Gergely Völgyi, Bálint Sinkó, Zsombor K. Nagy, Enikő Borbás
Publikováno v:
Periodica Polytechnica Chemical Engineering. 67:1-10
Solubility and permeability are key parameters for establishing in vitro-in vivo correlation for poorly water-soluble active pharmaceutical ingredients (APIs). Recent studies demonstrate that not only solubility, but also effective permeability of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81e2c8231c588785f33d4363b3c71372
https://doi.org/10.3311/ppch.20970
https://doi.org/10.3311/ppch.20970
Autor:
Bálint Sinkó, Vivien Bárdos, Dániel Vesztergombi, Szabina Kádár, Petra Malcsiner, Anne Moustie, Chantal Jouy, Krisztina Takács-Novák, Sebastien Grégoire
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1758 (2021)
Absorption through the skin of topically applied chemicals is relevant for both formulation development and safety assessment, especially in the early stages of development. However, the supply of human skin is limited, and the traditional in vitro m
Externí odkaz:
https://doaj.org/article/0a7f65e9216e43309bd3d7f6dabc0762
Publikováno v:
ADMET and DMPK, Vol 2, Iss 4, Pp 191-198 (2015)
Transdermal drug delivery has been growing extensively in the past decades, therefore new, reliable and cost-effective in vitro models were demanded to support the research and development on this field. Model membrane of PAMPA mimicking skin penetra
Externí odkaz:
https://doaj.org/article/5925ae0d73f846cea964df95c355ea95
Publikováno v:
International Journal of Pharmaceutics. 635:122692
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b80f51e69ee3217ba1159e75a91fe84
https://doi.org/10.1016/j.ijpharm.2023.122692
https://doi.org/10.1016/j.ijpharm.2023.122692
Autor:
Szabina Kádár, Petra Tőzsér, Brigitta Nagy, Attila Farkas, Zsombor K. Nagy, Oksana Tsinman, Konstantin Tsinman, Dóra Csicsák, Gergely Völgyi, Krisztina Takács-Novák, Enikő Borbás, Bálint Sinkó
Publikováno v:
The AAPS Journal. 24
The work aimed to develop the Absorption Driven Drug Formulation (ADDF) concept, which is a new approach in formulation development to ensure that the drug product meets the expected absorption rate. The concept is built on the solubility-permeabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21a2760169fbfad2a1127c3af785185a
https://doi.org/10.1208/s12248-021-00668-9
https://doi.org/10.1208/s12248-021-00668-9
Synthesis and Characterization of Long-Chain Tartaric Acid Diamides as Novel Ceramide-Like Compounds
Publikováno v:
Molecules, Vol 15, Iss 2, Pp 824-833 (2010)
Ceramides play a crucial role in the barrier function of the skin as well as in transmembrane signaling. In this study long aliphatic chain tartaric acid diamides able to replace ceramides in an in vitro model of the stratum corneum lipid matrix due
Externí odkaz:
https://doaj.org/article/6c51f42257c74849a167f4a816580012
Autor:
Chantal Jouy, Vivien Bárdos, Anne Moustie, Szabina Kádár, Sébastien Grégoire, Dániel Vesztergombi, Petra Malcsiner, Bálint Sinkó, Krisztina Takács-Novák
Publikováno v:
Pharmaceutics
Volume 13
Issue 11
Pharmaceutics, Vol 13, Iss 1758, p 1758 (2021)
Volume 13
Issue 11
Pharmaceutics, Vol 13, Iss 1758, p 1758 (2021)
Absorption through the skin of topically applied chemicals is relevant for both formulation development and safety assessment, especially in the early stages of development. However, the supply of human skin is limited, and the traditional in vitro m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c13f698b56747fa960855b389b26fa
http://europepmc.org/articles/PMC8625559
http://europepmc.org/articles/PMC8625559
Autor:
Szabina, Kádár, Petra, Tőzsér, Brigitta, Nagy, Attila, Farkas, Zsombor K, Nagy, Oksana, Tsinman, Konstantin, Tsinman, Dóra, Csicsák, Gergely, Völgyi, Krisztina, Takács-Novák, Enikő, Borbás, Bálint, Sinkó
Publikováno v:
The AAPS journal. 24(1)
The work aimed to develop the Absorption Driven Drug Formulation (ADDF) concept, which is a new approach in formulation development to ensure that the drug product meets the expected absorption rate. The concept is built on the solubility-permeabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ebda0b95d3e1bb09cafa0b0823805ec
https://pubmed.ncbi.nlm.nih.gov/34988721
https://pubmed.ncbi.nlm.nih.gov/34988721