Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Bàrbara Laviña"'
Autor:
Elisa Vázquez-Liébanas, Giuseppe Mocci, Weihan Li, Bàrbara Laviña, Avril Reddy, Claire O’Connor, Natalie Hudson, Zaher Elbeck, Ioannis Nikoloudis, Konstantin Gaengel, Michael Vanlandewijck, Matthew Campbell, Christer Betsholtz, Maarja Andaloussi Mäe
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113911- (2024)
Summary: Claudin-5 (CLDN5) is an endothelial tight junction protein essential for blood-brain barrier (BBB) formation. Abnormal CLDN5 expression is common in brain disease, and knockdown of Cldn5 at the BBB has been proposed to facilitate drug delive
Externí odkaz:
https://doaj.org/article/d34577273d7342149fefcf704bebdf82
Autor:
Ruslan Rust, Tunahan Kirabali, Lisa Grönnert, Berre Dogancay, Yanuar D. P. Limasale, Andrea Meinhardt, Carsten Werner, Bàrbara Laviña, Luka Kulic, Roger M. Nitsch, Christian Tackenberg, Martin E. Schwab
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
The distinct organization of the brain’s vasculature ensures the adequate delivery of oxygen and nutrients during development and adulthood. Acute and chronic pathological changes of the vascular system have been implicated in many neurological dis
Externí odkaz:
https://doaj.org/article/c41fbfe134e64b1f856f20b02966e067
Autor:
Naoki Honkura, Mark Richards, Bàrbara Laviña, Miguel Sáinz-Jaspeado, Christer Betsholtz, Lena Claesson-Welsh
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Different stimuli can induce dynamic changes in blood flow velocity, vessel diameter and permeability. Here the authors develop a multi-photon microscopy-based image analysis tool allowing the identification of vessels and the assessment of rapid cha
Externí odkaz:
https://doaj.org/article/5f724ed68afa4984a0c4a2a53150e86d
Autor:
Lukas Stanczuk, Ines Martinez-Corral, Maria H. Ulvmar, Yang Zhang, Bàrbara Laviña, Marcus Fruttiger, Ralf H. Adams, Dieter Saur, Christer Betsholtz, Sagrario Ortega, Kari Alitalo, Mariona Graupera, Taija Mäkinen
Publikováno v:
Cell Reports, Vol 10, Iss 10, Pp 1708-1721 (2015)
Pathological lymphatic diseases mostly affect vessels in specific tissues, yet little is known about organ-specific regulation of the lymphatic vasculature. Here, we show that the vascular endothelial growth factor receptor 3 (VEGFR-3)/p110α PI3-kin
Externí odkaz:
https://doaj.org/article/424c2c5533a044f5ab605d5b452552b5
Autor:
Colin Niaudet, Jennifer J Hofmann, Maarja A Mäe, Bongnam Jung, Konstantin Gaengel, Michael Vanlandewijck, Elisabet Ekvärn, M Dolores Salvado, Annika Mehlem, Sahar Al Sayegh, Liqun He, Thibaud Lebouvier, Marco Castro-Freire, Kan Katayama, Kjell Hultenby, Christine Moessinger, Philip Tannenberg, Sara Cunha, Kristian Pietras, Bàrbara Laviña, JongWook Hong, Tove Berg, Christer Betsholtz
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137949 (2015)
Despite its known expression in both the vascular endothelium and the lung epithelium, until recently the physiological role of the adhesion receptor Gpr116/ADGRF5 has remained elusive. We generated a new mouse model of constitutive Gpr116 inactivati
Externí odkaz:
https://doaj.org/article/6f2f517b62c14130b740db03e8f5de3c
Autor:
Bàrbara Laviña
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 1, p 70 (2016)
Recent major improvements in a number of imaging techniques now allow for the study of the brain in ways that could not be considered previously. Researchers today have well-developed tools to specifically examine the dynamic nature of the blood vess
Externí odkaz:
https://doaj.org/article/b7cc53a8db4d4bfda4c1a75cc86e1f0f
Autor:
Anna Dimberg, Bàrbara Laviña, Maria Georganaki, Lei Liu Conze, Hua Huang, Luuk van Hooren, Kalyani Vemuri, Tiarne van de Walle, Liqun He, Lei Zhang, Roberta Lugano, Mohanraj Ramachandran, Peetra U. Magnusson, Fredrik Pontén, Christer Betsholtz, Michael Bergqvist, Elisabetta Dejana, Anja Smits
Publikováno v:
Neuro Oncol
Background Tumor vessels in glioma are molecularly and functionally abnormal, contributing to treatment resistance. Proteins differentially expressed in glioma vessels can change vessel phenotype and be targeted for therapy. ELTD1 (Adgrl4) is an orph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810ec56d98bdf9c70cf044019567adcd
https://pubmed.ncbi.nlm.nih.gov/35015881
https://pubmed.ncbi.nlm.nih.gov/35015881
Autor:
S. Lu, Colin Niaudet, Cord Brakebusch, Bàrbara Laviña, Christer Betsholtz, Milena Petkova, Stefan Offermanns, Bongnam Jung
Publikováno v:
Angiogenesis
Niaudet, C, Petkova, M, Jung, B, Lu, S, Laviña, B, Offermanns, S, Brakebusch, C & Betsholtz, C 2019, ' Adgrf5 contributes to patterning of the endothelial deep layer in retina ', Angiogenesis, vol. 22, no. 4, pp. 491-505 . https://doi.org/10.1007/s10456-019-09674-0
Niaudet, C, Petkova, M, Jung, B, Lu, S, Laviña, B, Offermanns, S, Brakebusch, C & Betsholtz, C 2019, ' Adgrf5 contributes to patterning of the endothelial deep layer in retina ', Angiogenesis, vol. 22, no. 4, pp. 491-505 . https://doi.org/10.1007/s10456-019-09674-0
Neovascularization of the inner retinal space is a major cause of vision loss. In retinal angiomatous proliferation (RAP) syndrome, newly formed vessels originate from the retinal plexus and invade the inner retinal space. However, the molecular path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dfa84b3bc1b6d6dc48e2a0a3cc577a0
https://doi.org/10.1007/s10456-019-09674-0
https://doi.org/10.1007/s10456-019-09674-0
Autor:
Amaury Cazenave-Gassiot, David L. Silver, Susan E. Quaggin, Maarja Andaloussi Mäe, Bàrbara Laviña, Elisa Vazquez-Liebanas, Bongnam Jung, Juat Chin Foo, Marie Jeansson, Annika Keller, Yvette Zarb, Michael Vanlandewijck, Markus R. Wenk, Liqun He, Khayrun Nahar, Chengua Gu, Bryan C. Tan, Eugene C. Butcher, Sofia Nordling, Christer Betsholtz, Xidan Li
Publikováno v:
Circulation Research
Rationale: Pericytes are capillary mural cells playing a role in stabilizing newly formed blood vessels during development and tissue repair. Loss of pericytes has been described in several brain disorders, and genetically induced pericyte deficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264129839b6a627479da7aa593cec962
https://doi.org/10.5167/uzh-196164
https://doi.org/10.5167/uzh-196164
Autor:
Bàrbara Laviña, Naoki Honkura, Miguel Sáinz-Jaspeado, Mark Richards, Lena Claesson-Welsh, Christer Betsholtz
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications
Nature Communications
The vasculature undergoes changes in diameter, permeability and blood flow in response to specific stimuli. The dynamics and interdependence of these responses in different vessels are largely unknown. Here we report a non-invasive technique to study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73782fe58d651c897787df8e37c7c02
http://link.springer.com/article/10.1038/s41467-018-04929-8
http://link.springer.com/article/10.1038/s41467-018-04929-8