Phosphorylation of multiple CD3 zeta tyrosine residues leads to formation of pp21 in vitro and in vivo. Structural changes upon T cell receptor stimulation

Autor: S, Koyasu, D J, McConkey, L K, Clayton, S, Abraham, B, Yandava, T, Katagiri, P, Moingeon, T, Yamamoto, E L, Reinherz

Publikováno v: The Journal of biological chemistry. 267(5)

T lymphocyte activation resulting from antigen recognition involves a protein tyrosine kinase pathway which triggers phosphorylation of several cellular substrates including the CD3 zeta subunit of the T cell receptor (TCR) to form pp21. The homologo

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https://pubmed.ncbi.nlm.nih.gov/1531339

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The impact of sMICA/sMICB on immunochemotherapy outcomes in newly diagnosed diffuse large B-cell lymphoma.

Autor: Yoon SE; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Park S; Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Cho J; Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Ryu KJ; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Korea., Yandava B; Samyang Biopharm USA, Cambridge, MA, United States., Lee S; Division of Hematology-Oncology, Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea., Kim SJ; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Kim WS; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Publikováno v: Frontiers in oncology [Front Oncol] 2023 Nov 16; Vol. 13, pp. 1194315. Date of Electronic Publication: 2023 Nov 16 (Print Publication: 2023).

The CD3 zeta cytoplasmic domain mediates CD2-induced T cell activation.

Autor: Howard FD; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, Massachusetts., Moingeon P, Moebius U, McConkey DJ, Yandava B, Gennert TE, Reinherz EL

Publikováno v: The Journal of experimental medicine [J Exp Med] 1992 Jul 01; Vol. 176 (1), pp. 139-45.