Výsledky vyhledávání - "B, Wegrzynski"

Characterization of a 78-residue fragment of c-Raf-1 that comprises a minimal binding domain for the interaction with Ras-GTP

Autor: Kathleen Prinzo, Joseph E. LoSardo, B. Wegrzynski, S.E. Kiefer, S. D. Emerson, J. E. Scheffler, Kwei-Lan Tsao, Anthony Neri, Eva Bekesi, David S. Waugh

Publikováno v: Journal of Biological Chemistry. 269:22340-22346

Four overlapping peptide fragments of human c-Raf-1 (residues 55-132, 55-117, 77-132, and 77-117) were expressed in Escherichia coli as carboxyl-terminal extensions of maltose binding protein (MBP). The MBP-Raf fusions were purified by affinity chrom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87f1edc085e5dede0d57155fe12d76b1
https://doi.org/10.1016/s0021-9258(17)31795-7

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ChemInform Abstract: Natural Products. Antitubulin Effect of Congeners of N-Acetylcolchinyl Methyl Ether: Synthesis of Optically Active 5- Acetamidodeaminocolchinyl Methyl Ether and of Demethoxy Analogues of Deaminocolchinyl Methyl Ether

Autor: Herman J. C. Yeh, Arnold Brossi, Ernest Hamel, B. Wegrzynski, O. Boye, V. Toome

Publikováno v: ChemInform. 24

Trimethoxy-substituted dihydrodibenzocycloheptenes 4–7, required for a structure–activity study measuring the inhibition of tubulin polymerization in vitro, were synthesized by four different routes: (1) Synthesis of 4 was achieved from 2,3-dimet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe632e4ee1faae052504e4632b3df251
https://doi.org/10.1002/chin.199304255

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Natural products. Antitubulin effect of congeners of N-acetylcolchinyl methyl ether: synthesis of optically active 5-acetamidodeaminocolchinyl methyl ether and of demethoxy analogues of deaminocolchinyl methyl ether

Autor: Arnold Brossi, O. Boye, Herman J. C. Yeh, Ernest Hamel, B. Wegrzynski, V. Toome

Publikováno v: Canadian Journal of Chemistry. 70:1237-1249

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::823cc1deff4ce9baa87f9bfb07d817c8
https://doi.org/10.1139/v92-160

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A fast and simplein situ method for the determination of the absolute configuration of amino acid esters using the chiroptical properties of their Eu(FOD)3 complexes

Autor: B Wegrzynski, V Toome

Publikováno v: Amino Acids. 3:195-203

The NMR shift reagent, Europium(III)-tris-(1,1,1,2,2,3,3)-heptafluoro-7,7-dimethyl-4-6-octanedione [Eu(fod)3], complexes efficiently withα-amino acid esters in chloroform. These complexes exhibit characteristic circular dichroism (CD) spectral patte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf99890126ffe8bb27dc80835d685a0
https://doi.org/10.1007/bf00806784

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Characterization of a 78-residue fragment of c-Raf-1 that comprises a minimal binding domain for the interaction with Ras-GTP

Autor: J E, Scheffler, D S, Waugh, E, Bekesi, S E, Kiefer, J E, LoSardo, A, Neri, K M, Prinzo, K L, Tsao, B, Wegrzynski, S D, Emerson

Publikováno v: The Journal of biological chemistry. 269(35)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::54c5f0203e34fd3a0f6a5d5eab19f8d6
https://pubmed.ncbi.nlm.nih.gov/8071362

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Application of MDPF and fluorescamine XV chiroptical properties of MDPF condensation compounds with dipeptides in situ

Autor: V. Toome, B. Wegrzynski

Publikováno v: Biochemical and Biophysical Research Communications. 114:433-439

2-Methoxy-2,4-diphenyl-3(2 H )-furanone (MDPF) reacts readily with the free amino group of a dipeptide to form a pyrrolinone-type chromophore with absorption maxima at 275–285 and 370–390 nm. A simple test tube procedure is described which allows

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ff3444d18b2863b26d48a1082c97e4
https://doi.org/10.1016/0006-291x(83)90798-2

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Application of fluorescamine XII. Chiroptical properties of fluorescamine condensation compounds with some less common α-amino acids

Autor: V. Toome, B. Wegrzynski

Publikováno v: Biochemical and Biophysical Research Communications. 92:447-451

Fluorescamine (FLURAM®) reacts efficiently with less common chiral α-amino acids to form pyrrolinone-type chromophores. The characteristic Cotton effects at 324-300 and at 290-263 nm can be related to the absolute configuration of the parent α-ami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2bc80d5bab24de0790e03b312eb23f
https://doi.org/10.1016/0006-291x(80)90353-8

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Application Of Fluorescamine Xiv1. Determination Of Optical Purity Of A Small Amount Of Amino Acids By The Fluorescamine Method

Autor: B. Wegrzynski, V. Toome

Publikováno v: Analytical Letters. 14:1725-1733

A new simple and fast micro method has been established to determine the optical purity of a small amount of amino acids (0.1–1 μg/ml). The amino acids react readily with fluorescamine to form pyrrolinone-type chromophores, which show strong CD ba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c43cdea12fce29429ec02a32fb485dd7
https://doi.org/10.1080/00032718108059835

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Chiroptical Properties of Fluorescamine Derivatives of Chiral Primary Aminesin situ

Autor: B. Wegrzynski, J. Dell, V. Toome

Publikováno v: Spectroscopy Letters. 10:747-756

Primary amines react efficiently with fluorescamine (FLURAM®) to form pyrrolinone-type chromophores with long wavelength absorption maxima at 380–410 nm. When the primary amine is chiral, these chromophoric derivatives exhibit characteristic Cotto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6dfd9f9c116d41c5e11ac081d80c1aae
https://doi.org/10.1080/00387017708065008

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