Zobrazeno 1 - 10
of 53
pro vyhledávání: '"B, Van Snick"'
Autor:
B. Bekaert, B. Van Snick, K. Pandelaere, J. Dhondt, G. Di Pretoro, T. De Beer, C. Vervaet, V. Vanhoorne
Publikováno v:
International Journal of Pharmaceutics: X, Vol 4, Iss , Pp 100110- (2022)
In this study, an empirical predictive model was developed based on the quantitative relationships between blend properties, critical quality attributes (CQA) and critical process parameters (CPP) related to blending and tableting. The blend uniformi
Externí odkaz:
https://doaj.org/article/ddf887247a9e45bfbe253f7fed59de88
Autor:
T. De Beer, Valérie Vanhoorne, Jens Dhondt, Chris Vervaet, Maxim Verstraeten, Ashish Kumar, B. Van Snick, G. Di Pretoro, Kenny Pandelaere
Publikováno v:
International Journal of Pharmaceutics. 556:200-216
Screw feeders are integrated as dispensing units in most continuous manufacturing platforms. Hence, characterizing and modelling the residence time distribution (RTD) of materials in feeders is indispensable to understand the traceability of raw mate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b165edc1f24061875aacf49ca493702
https://doi.org/10.1016/j.ijpharm.2018.11.076
https://doi.org/10.1016/j.ijpharm.2018.11.076
Autor:
Jens Dhondt, J. Boeckx, Chris Vervaet, L. Penne, J. Vogeleer, W. Grymonpré, Valérie Vanhoorne, B. Bekaert, B. Van Snick, T. De Beer
Publikováno v:
INTERNATIONAL JOURNAL OF PHARMACEUTICS
In this study, a quantitative relationship between material properties, process settings and screw feeding responses of a high-throughput feeder was established via multivariate models (PLS). Thirteen divergent powders were selected and characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69244f00600ee256236ef75e29f0ee38
https://biblio.ugent.be/publication/8740275
https://biblio.ugent.be/publication/8740275
Autor:
B, Bekaert, B, Van Snick, K, Pandelaere, J, Dhondt, G, Di Pretoro, T, De Beer, C, Vervaet, V, Vanhoorne
Publikováno v:
INTERNATIONAL JOURNAL OF PHARMACEUTICS
This study determined the feasibility of long-term continuous powder feeding and its effect on the overall process performance. Additionally, quantitative relationships were established between material properties, process settings and screw feeding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ec01ba8b7c477350e87497693a5f5a
https://doi.org/10.1016/j.ijpharm.2022.121454
https://doi.org/10.1016/j.ijpharm.2022.121454
Autor:
F. Detobel, Chris Vervaet, T. De Beer, J.P. Remon, B. Blahova Prudilova, B. Van Snick, Valérie Vanhoorne, W. Grymonpré
Publikováno v:
International Journal of Pharmaceutics. 550:477-485
With the current transformation of the pharmaceutical industry towards continuous manufacturing, there is an inherent need to embrace this concept already during the early stages of drug formulation. Therefore, this research paper investigated the fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4850abfb77cb1140f0cf2b03dbe5ddff
https://doi.org/10.1016/j.ijpharm.2018.09.006
https://doi.org/10.1016/j.ijpharm.2018.09.006
Autor:
J.P. Remon, Chris Vervaet, F. Detobel, B. Blahova Prudilova, Valérie Vanhoorne, T. De Beer, W. Grymonpré, B. Van Snick
Publikováno v:
International Journal of Pharmaceutics. 548:54-61
Despite the high quantities of tablets produced daily, many tableting processes are still operated at sub-optimal settings and hence lack the necessary flexibility to mitigate for possible process deviations. However, to ensure this flexibility on ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb98cc10cd5606de8a2e5a142b468566
https://doi.org/10.1016/j.ijpharm.2018.06.047
https://doi.org/10.1016/j.ijpharm.2018.06.047
Autor:
Tom Hellemans, Aseel Samaro, Matthieu Boone, Valérie Vanhoorne, Jean Paul Remon, L. Van Hoorebeke, W. Grymonpré, B. Van Snick, Chris Vervaet, G. Verstraete
Publikováno v:
International Journal of Pharmaceutics. 536:318-325
It was the aim of this study to develop high drug loaded (>30%, w/w), thermoplastic polyurethane (TPU)-based dosage forms via fused deposition modelling (FDM). Model drugs with different particle size and aqueous solubility were pre-processed in comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::858c94805d7c3067edcd21487d3b89aa
https://doi.org/10.1016/j.ijpharm.2017.12.002
https://doi.org/10.1016/j.ijpharm.2017.12.002
Autor:
Valérie Vanhoorne, Jens Dhondt, Edina Szabó, N. Bostijn, T. De Beer, Alexander Ryckaert, W. Dhondt, Chris Vervaet, B. Van Snick
Publikováno v:
INTERNATIONAL JOURNAL OF PHARMACEUTICS
In this study, the volumetric and gravimetric feeding behavior of 15 pharmaceutical powders on a low feed rate feeder was correlated with their material properties through a multivariate approach. The powders under investigation differ substantially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7aa8dbfc98beef105f59b445482d55
https://biblio.ugent.be/publication/8610747
https://biblio.ugent.be/publication/8610747
Autor:
Jens Dhondt, Kenny Pandelaere, G. Di Pretoro, J.P. Remon, Chris Vervaet, T. De Beer, Valérie Vanhoorne, B. Van Snick, W. Grymonpré
Publikováno v:
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Based on characterization of a wide range of fillers and APIs, thirty divergent blends were composed and subsequently compressed on a rotary tablet press, varying paddle speed and turret speed. The tablet weight variability was determined of 20 grab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27852bd3d579feef79e883ccc783267
https://biblio.ugent.be/publication/8609698
https://biblio.ugent.be/publication/8609698
Autor:
B. Van Snick, J.P. Remon, J. Holman, T. De Beer, Valérie Vanhoorne, Chris Vervaet, Ashish Kumar
Publikováno v:
International journal of pharmaceutics. 529(1-2)
In this work a continuous direct compression process was developed for a low-dosed drug product. Each unit operation of the GEA CDC-50 system was thoroughly investigated. This paper aimed to tackle the macroscopic and microscopic blend uniformity cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4e7026b64deb38880394b521fd2d88
https://pubmed.ncbi.nlm.nih.gov/28684361
https://pubmed.ncbi.nlm.nih.gov/28684361