Zobrazeno 1 - 10
of 119
pro vyhledávání: '"B, Schaffhausen"'
Publikováno v:
Molecular and Cellular Biology. 13:1657-1665
We identified a serine/threonine protein kinase that is associated with and phosphorylates phosphoinositide 3-kinase (PtdIns 3-kinase). The serine kinase phosphorylates both the 85- and 110-kDa subunits of PtdIns 3-kinase and purifies with it from ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::462af9e68da22a73390337fd60840e98
https://doi.org/10.1128/mcb.13.3.1657
https://doi.org/10.1128/mcb.13.3.1657
Autor:
B. Schaffhausen
Murine polyomavirus (polyoma) is widely distributed in the mouse population. This article discusses the structure and life cycle of the virus. The virus particle consists of a 5.3 kbp circular, double-stranded DNA molecule, cellular histones, and thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0158daee97dedcb1b0f7fc20f15ce3f
https://doi.org/10.1016/b978-012374410-4.00474-x
https://doi.org/10.1016/b978-012374410-4.00474-x
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 5(2)
The expression of polyomavirus large T antigen in stably transfected C2 myoblast cells inhibits terminal differentiation without inducing a transformed phenotype. In the present work, we report on the lifting of this inhibition by a mutation that pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0b817f345be1e76e59b7033b4cb484ed
https://pubmed.ncbi.nlm.nih.gov/8180137
https://pubmed.ncbi.nlm.nih.gov/8180137
Autor:
C L, Carpenter, K R, Auger, M, Chanudhuri, M, Yoakim, B, Schaffhausen, S, Shoelson, L C, Cantley
Publikováno v:
The Journal of biological chemistry. 268(13)
Tyrosine-phosphorylated peptides based on the regions of polyoma virus middle t antigen and the platelet-derived growth factor receptor that bind phosphoinositide 3-kinase are shown to activate this enzyme 2-3-fold in vitro. The concentrations of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::43e429e3e186370fd8ba73d7a649b34a
https://pubmed.ncbi.nlm.nih.gov/7683653
https://pubmed.ncbi.nlm.nih.gov/7683653
Autor:
B, Schaffhausen
Publikováno v:
CRC critical reviews in biochemistry. 13(3)
The small DNA-containing viruses, SV40 and polyoma, transform cells in vitro and induce tumors in vivo. For both viruses two genes required for transformation have been found. The genes required for transformation are also involved in productive infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef026118cf1f00ac0db743e113dd0f91
https://pubmed.ncbi.nlm.nih.gov/6293767
https://pubmed.ncbi.nlm.nih.gov/6293767
Publikováno v:
The Journal of biological chemistry. 257(21)
Middle T antigen of polyoma virus has an associated tyrosine kinase activity which phosphorylates tyrosine residue 315 on middle T in immunoprecipitates. A peptide representing the sequence of middle T from residue 311 to 319 has been synthesized. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b82b04ef53cc0b83257cedf1a0d19ea7
https://pubmed.ncbi.nlm.nih.gov/6290466
https://pubmed.ncbi.nlm.nih.gov/6290466
Publikováno v:
Gene amplification and analysis. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9b850754f74adc1571ffaf248e7d55e
https://pubmed.ncbi.nlm.nih.gov/6400699
https://pubmed.ncbi.nlm.nih.gov/6400699
Publikováno v:
Federation proceedings. 45(11)
We have used the DNA tumor virus polyoma as a model system to examine whether the phosphatidylinositol (PI) turnover pathway is a critical target for transforming gene products. Polyoma-infected cells show elevated levels of polyphosphoinositides and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96e97d906432e0b247dd66257715f618
https://pubmed.ncbi.nlm.nih.gov/3019785
https://pubmed.ncbi.nlm.nih.gov/3019785
Publikováno v:
Chemischer Informationsdienst. Organische Chemie. 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be90cbbf596d8fa0689e700a1936afb5
https://doi.org/10.1002/chin.197144094
https://doi.org/10.1002/chin.197144094
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