Zobrazeno 1 - 10
of 349
pro vyhledávání: '"B, Saltzman"'
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107283- (2023)
Summary: The cardiac fibroblast interacts with an extracellular matrix (ECM), enabling myofibroblast maturation via a process called mechanosensing. Although in the aging male heart, ECM is stiffer than in the young mouse, myofibroblast development i
Externí odkaz:
https://doaj.org/article/c8cfa963abd647768375a7e05f7bdf34
Autor:
Tiffany Chern, Annita Achilleos, Xuefei Tong, Matthew C. Hill, Alexander B. Saltzman, Lucas C. Reineke, Arindam Chaudhury, Swapan K. Dasgupta, Yushi Redhead, David Watkins, Joel R. Neilson, Perumal Thiagarajan, Jeremy B. A. Green, Anna Malovannaya, James F. Martin, David S. Rosenblatt, Ross A. Poché
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Combined methylmalonic acidemia (MMA) and hyperhomocysteinemias are inborn errors of vitamin B12 metabolism, and mutations in the transcriptional regulators HCFC1 and RONIN (THAP11) underlie some forms of these disorders. Here the authors generated m
Externí odkaz:
https://doaj.org/article/18e20d90d2e9439192ddff6d1fb4cef0
Autor:
Varduhi Petrosyan, Lacey E. Dobrolecki, Lillian Thistlethwaite, Alaina N. Lewis, Christina Sallas, Ramakrishnan R. Srinivasan, Jonathan T. Lei, Vladimir Kovacevic, Predrag Obradovic, Matthew J. Ellis, C. Kent Osborne, Mothaffar F. Rimawi, Anne Pavlick, Maryam Nemati Shafaee, Heidi Dowst, Antrix Jain, Alexander B. Saltzman, Anna Malovannaya, Elisabetta Marangoni, Alana L. Welm, Bryan E. Welm, Shunqiang Li, Gerburg M. Wulf, Olmo Sonzogni, Chen Huang, Suhas Vasaikar, Susan G. Hilsenbeck, Bing Zhang, Aleksandar Milosavljevic, Michael T. Lewis
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105799- (2023)
Summary: Although systemic chemotherapy remains the standard of care for TNBC, even combination chemotherapy is often ineffective. The identification of biomarkers for differential chemotherapy response would allow for the selection of responsive pat
Externí odkaz:
https://doaj.org/article/2b0f86504c374089a6c4e5c09a09e1cb
Autor:
Eliana B. Saltzman, MD, Daniel R. Evans, MSc, Albert Anastasio, MD, Ndeye Guisse, BS, Elshaday S. Belay, MD, Oke A. Anakwenze, MD, MBA, Mark J. Gage, MD, Tyler S. Pidgeon, MD, Marc J. Richard, MD, David S. Ruch, MD, Christopher S. Klifto, MD
Publikováno v:
JSES International, Vol 5, Iss 6, Pp 1111-1118 (2021)
Introduction: We hypothesized that the modified Fragility Index (mFI), which predicts surgical complications, would be applicable to surgical complications in patients older than 50 years with distal humerus fractures (DHF). Methods: We retrospective
Externí odkaz:
https://doaj.org/article/ab2dcb3d2c14464a83b6b675cec6b3fc
Autor:
Daniel R. Evans, MSc, Eliana B. Saltzman, MD, Albert T. Anastasio, MD, Ndeye F. Guisse, BS, Elshaday S. Belay, MD, Tyler S. Pidgeon, MD, Marc J. Richard, MD, David S. Ruch, MD, Oke A. Anakwenze, MD, MBA, Mark J. Gage, MD, Christopher S. Klifto, MD
Publikováno v:
JSES International, Vol 5, Iss 2, Pp 212-219 (2021)
Hypothesis: We hypothesized that the modified Fragility Index (mFI) would predict complications in patients older than 50 years who underwent operative intervention for a proximal humerus fracture. Methods: We retrospectively reviewed the American Co
Externí odkaz:
https://doaj.org/article/51a2e73a6edf4b66ba6fcfdc5164dd36
Autor:
Shankha Satpathy, Eric J. Jaehnig, Karsten Krug, Beom-Jun Kim, Alexander B. Saltzman, Doug W. Chan, Kimberly R. Holloway, Meenakshi Anurag, Chen Huang, Purba Singh, Ari Gao, Noel Namai, Yongchao Dou, Bo Wen, Suhas V. Vasaikar, David Mutch, Mark A. Watson, Cynthia Ma, Foluso O. Ademuyiwa, Mothaffar F. Rimawi, Rachel Schiff, Jeremy Hoog, Samuel Jacobs, Anna Malovannaya, Terry Hyslop, Karl R. Clauser, D. R. Mani, Charles M. Perou, George Miles, Bing Zhang, Michael A. Gillette, Steven A. Carr, Matthew J. Ellis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Connecting genomics and proteomics allows the development of more efficient and specific treatments for cancer. Here, the authors develop proteogenomic methods to defining cancer signaling in-vivo starting from core needle biopsies and with applicati
Externí odkaz:
https://doaj.org/article/1139337b9d47460b818a84e3816a1de9
Autor:
Mariah J. Berner, Lily Baek, Junegoo Lee, Philip L. Lorenzi, Mei Leng, Alexander B. Saltzman, Anna Malovannaya, Lacey E. Dobrolecki, Christina Sallas, Michael T. Lewis, Gloria V. Echeverria
Publikováno v:
Cancer Research. 83:P6-11
BACKGROUND: Nearly 50% of patients with triple negative breast cancer (TNBC) treated with neoadjuvant chemotherapy (NACT) retain residual tumors resulting in high rates of metastatic relapse and poor overall survival. Residual tumors surviving NACT (
Autor:
Jonathan T. Lei, Chen Huang, Ramakrishnan R. Srinivasan, Suhas Vasaikar, Lacey E. Dobrolecki, Alaina N. Lewis, Na Zhao, Jin Cao, Susan G. Hilsenbeck, C. Kent Osborne, Mothaffar Rimawi, Matthew J. Ellis, Varduhi Petrosyan, Alexander B. Saltzman, Anna Malovannaya, John D. Landua, Bo Wen, Antrix Jain, Gerburg M. Wulf, Shunqiang Li, Daniel C. Kraushaar, Tao Wang, Xi Chen, Gloria V. Echeverria, Meenakshi Anurag, Bing Zhang, Michael T. Lewis
Publikováno v:
Cancer Research. 83:P2-23
Background: Triple-negative breast cancer (TNBC) patients frequently receive combination chemotherapy treatment, but a direct comparison of response to carboplatin, docetaxel, and their combination in 50 TNBC patient-derived xenografts (PDXs) showed
Autor:
Eliana B. Saltzman, Jay M. Levin, Anna-Maria B. Dagher, Michael Messer, Ryan Kimball, John Lohnes, Bert R. Mandelbaum, Riley J. Williams, Annuziato Amendola, George Chiampas, Brian C. Lau
Publikováno v:
Journal of ISAKOS.
Autor:
Suhail K. Mithani, Amanda N. Fletcher, Nicholas Said, Eliana B. Saltzman, Elizabeth P. Wahl, Christopher S. Klifto
Publikováno v:
Hand (N Y)
Background: Scaphoid nonunion advanced collapse (SNAC) is a common form of wrist arthritis, the treatment of which depends on the arthritic stage. The Vender classification serves to describe SNAC arthritis based on a single posteroanterior (PA) radi