Zobrazeno 1 - 10
of 239
pro vyhledávání: '"B, Renstrom"'
Autor:
A. James Liedtke, T. L. Mulnix, Adrian D. Nunn, Charles K. Stone, Robert J. Nickles, Bruce L. Kuczynski, B. Renstrom, William L. Rumsey, S. H. Nellis
Publikováno v:
Circulation. 92:1246-1253
Background A new nitroimidazole complex, 99m Tc-propylene amine oxime-1,2-nitroimidazole (BMS-181321), has been developed to allow the positive imaging of hypoxic myocardium by standard gamma camera techniques. Methods and Results To determine the my
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 269:H246-H253
The purpose of this report was to directly measure the influence of antecedent ischemia or repetitive ischemia on subsequent rates of intermediary metabolism, specifically exogenous glucose utilization and fatty acid oxidation, with the use of myocar
Myocardial function and metabolism in pig hearts after relief from chronic partial coronary stenosis
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 267:H1312-H1319
Metabolic behavior was compared during acute extracorporeal reperfusion after removal of a chronic 4-day partial coronary stenosis in eight pig hearts (RCS group) and during comparable extracorporeal perfusion in seven chronically prepared hearts (Sh
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 265:H1614-H1622
The purpose of these studies was to evaluate metabolic behavior in a 4-day reperfusion model in pigs after induction of subendocardial infarction. Two groups of swine [sham and intervention (Int) groups, n = 7) and 10 hearts per group, respectively]
Publikováno v:
Circulation Research. 71:689-700
Studies were conducted in extracorporeally perfused, intact, working pig hearts to determine whether, in heart muscle, trace-labeled deoxyglucose serves as an accurate marker of glycolytic flux in reperfusion after exposures to mild to moderate regio
Distribution of carbon flux within fatty acid utilization during myocardial ischemia and reperfusion
Publikováno v:
Circulation Research. 69:779-790
Twenty-nine intact, working pig hearts were extracorporeally perfused and divided into two study groups (16 Aerobic and 13 Ischemic/Reflow hearts). Step function, equilibrium labeling with [14C]palmitate was used to develop uptake and washout curves
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 259:H317-H323
We previously reported in working swine hearts a preferred use of fatty acids during early myocardial reperfusion. The purpose of these studies was to test whether this pattern of substrate oxidation was the result of excess energy demands during mec
Autor:
B. Renstrom, A. J. Liedtke
Publikováno v:
Basic Research in Cardiology. 90:279-281
The purpose of this precis is to state and support a personal viewpoint concerning intermediary metabolism and substrate utilization in stunned and reperfused myocardium following an interval of nonnecrotizing myocardial ischemia. The data in support
Autor:
B, Renstrom, S, Rommelfanger, C K, Stone, T R, DeGrado, K J, Carlson, E, Scarbrough, R J, Nickles, A J, Liedtke, J E, Holden
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 39(10)
To study the sensitivity of two fatty acid tracers to changes in beta-oxidation, the myocardial retention kinetics of 125I-iodine-15-(p-iodophenyl)-3(R,S)-methylpentadecanoic acid (BMIPP) and 14-18F-fluoro-6-thia-heptadecanoic acid (FTHA) were compar
Autor:
C K, Stone, R A, Pooley, T R, DeGrado, B, Renstrom, R J, Nickles, S H, Nellis, A J, Liedtke, J E, Holden
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 39(10)
The fatty acid tracer 14-18F-fluoro-6-thia-heptadecanoic acid (FTHA) is a metabolically trapped tracer of exogenous fatty acid utilization. The objectives of this study were to determine the relationship of FTHA uptake to changes in perfusion and fat