Zobrazeno 1 - 10
of 237
pro vyhledávání: '"B, Neuhauser"'
Autor:
Dale A. Begley, Debra M. Krupke, John P. Sundberg, Emily L. Jocoy, Joel E. Richardson, Steven B. Neuhauser, Carol J. Bult
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 4 (2023)
Externí odkaz:
https://doaj.org/article/b28c3576686e494f9189eab951250d02
Autor:
Xing Yi Woo, Anuj Srivastava, Philip C. Mack, Joel H. Graber, Brian J. Sanderson, Michael W. Lloyd, Mandy Chen, Sergii Domanskyi, Regina Gandour-Edwards, Rebekah A. Tsai, James Keck, Mingshan Cheng, Margaret Bundy, Emily L. Jocoy, Jonathan W. Riess, William Holland, Stephen C. Grubb, James G. Peterson, Grace A. Stafford, Carolyn Paisie, Steven B. Neuhauser, R. Krishna Murthy Karuturi, Joshy George, Allen K. Simons, Margaret Chavaree, Clifford G. Tepper, Neal Goodwin, Susan D. Airhart, Primo N. Lara, Thomas H. Openshaw, Edison T. Liu, David R. Gandara, Carol J. Bult
Publikováno v:
Cancer Res
Cancer research, vol 82, iss 22
Cancer research, vol 82, iss 22
Patient-derived xenograft (PDX) models are an effective preclinical in vivo platform for testing the efficacy of novel drugs and drug combinations for cancer therapeutics. Here we describe a repository of 79 genomically and clinically annotated lung
Autor:
Carol J. Bult, David R. Gandara, Edison T. Liu, Thomas H. Openshaw, Primo N. Lara, Susan D. Airhart, Neal Goodwin, Clifford G. Tepper, Margaret Chavaree, Allen K. Simons, Joshy George, R. Krishna Murthy Karuturi, Steven B. Neuhauser, Carolyn Paisie, Grace A. Stafford, James G. Peterson, Stephen C. Grubb, William Holland, Jonathan W. Riess, Emily L. Jocoy, Margaret Bundy, Mingshan Cheng, James Keck, Rebekah A. Tsai, Regina Gandour-Edwards, Sergii Domanskyi, Mandy Chen, Michael W. Lloyd, Brian J. Sanderson, Joel H. Graber, Philip C. Mack, Anuj Srivastava, Xing Yi Woo
Patient-derived xenograft (PDX) models are an effective preclinical in vivo platform for testing the efficacy of novel drugs and drug combinations for cancer therapeutics. Here we describe a repository of 79 genomically and clinically annotated lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5cefc3df68748c1456699cbfa512e4c
https://doi.org/10.1158/0008-5472.c.6514248.v1
https://doi.org/10.1158/0008-5472.c.6514248.v1
Autor:
Carol J. Bult, David R. Gandara, Edison T. Liu, Thomas H. Openshaw, Primo N. Lara, Susan D. Airhart, Neal Goodwin, Clifford G. Tepper, Margaret Chavaree, Allen K. Simons, Joshy George, R. Krishna Murthy Karuturi, Steven B. Neuhauser, Carolyn Paisie, Grace A. Stafford, James G. Peterson, Stephen C. Grubb, William Holland, Jonathan W. Riess, Emily L. Jocoy, Margaret Bundy, Mingshan Cheng, James Keck, Rebekah A. Tsai, Regina Gandour-Edwards, Sergii Domanskyi, Mandy Chen, Michael W. Lloyd, Brian J. Sanderson, Joel H. Graber, Philip C. Mack, Anuj Srivastava, Xing Yi Woo
Supplementary Table from A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non–Small Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b1a58d4d6ddc9eaba431d6c2bee5b6
https://doi.org/10.1158/0008-5472.22432782
https://doi.org/10.1158/0008-5472.22432782
Autor:
Carol J. Bult, David R. Gandara, Edison T. Liu, Thomas H. Openshaw, Primo N. Lara, Susan D. Airhart, Neal Goodwin, Clifford G. Tepper, Margaret Chavaree, Allen K. Simons, Joshy George, R. Krishna Murthy Karuturi, Steven B. Neuhauser, Carolyn Paisie, Grace A. Stafford, James G. Peterson, Stephen C. Grubb, William Holland, Jonathan W. Riess, Emily L. Jocoy, Margaret Bundy, Mingshan Cheng, James Keck, Rebekah A. Tsai, Regina Gandour-Edwards, Sergii Domanskyi, Mandy Chen, Michael W. Lloyd, Brian J. Sanderson, Joel H. Graber, Philip C. Mack, Anuj Srivastava, Xing Yi Woo
Supplementary Figure from A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non–Small Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b25cbe2de39330bf2d95fba69463be
https://doi.org/10.1158/0008-5472.22432803
https://doi.org/10.1158/0008-5472.22432803
Autor:
Carol J. Bult, Atul J. Butte, Helen Parkinson, Marcel Kool, Stefan M. Pfister, Frédéric Amant, S. John Weroha, Alana Welm, David M. Weinstock, Robert J. Wechsler-Reya, Emilie Vinolo, Livio Trusolino, Je Kyung Seong, Oscar M. Rueda, Daniel S. Peeper, James M. Olson, Steven B. Neuhauser, Enzo Medico, Jeremy Mason, K.C. Kent Lloyd, Michael T. Lewis, Tin O. Khor, Kristel Kemper, Jos Jonkers, Peter J. Houghton, Els Hermans, Melissa A. Haendel, Danielle Greenawalt, Neal C. Goodwin, Kristopher K. Frese, Stephane Ferretti, Yvonne A. Evrard, Olivier Duchamp, James H. Doroshow, Jonathan R. Dry, Heidi Dowst, Dominic A. Clark, Amanda L. Christie, Carlos Caldas, Annette T. Byrne, Matthew H. Brush, Alejandra Bruna, Andrea Bertotti, Debra M. Krupke, Dale A. Begley, Patrick Dunn, Jeffrey A. Wiser, Zhiping Gu, Sebastian Brabetz, Mark A. Murakami, Giorgio Inghirami, Theodore Goldstein, Nathalie Conte, Terrence F. Meehan
Patient-derived tumor xenograft (PDX) mouse models have emerged as an important oncology research platform to study tumor evolution, mechanisms of drug response and resistance, and tailoring chemotherapeutic approaches for individual patients. The la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0373627dabe0ae72d83c81ddf8478d17
https://doi.org/10.1158/0008-5472.c.6510291.v1
https://doi.org/10.1158/0008-5472.c.6510291.v1
Autor:
Carol J. Bult, Atul J. Butte, Helen Parkinson, Marcel Kool, Stefan M. Pfister, Frédéric Amant, S. John Weroha, Alana Welm, David M. Weinstock, Robert J. Wechsler-Reya, Emilie Vinolo, Livio Trusolino, Je Kyung Seong, Oscar M. Rueda, Daniel S. Peeper, James M. Olson, Steven B. Neuhauser, Enzo Medico, Jeremy Mason, K.C. Kent Lloyd, Michael T. Lewis, Tin O. Khor, Kristel Kemper, Jos Jonkers, Peter J. Houghton, Els Hermans, Melissa A. Haendel, Danielle Greenawalt, Neal C. Goodwin, Kristopher K. Frese, Stephane Ferretti, Yvonne A. Evrard, Olivier Duchamp, James H. Doroshow, Jonathan R. Dry, Heidi Dowst, Dominic A. Clark, Amanda L. Christie, Carlos Caldas, Annette T. Byrne, Matthew H. Brush, Alejandra Bruna, Andrea Bertotti, Debra M. Krupke, Dale A. Begley, Patrick Dunn, Jeffrey A. Wiser, Zhiping Gu, Sebastian Brabetz, Mark A. Murakami, Giorgio Inghirami, Theodore Goldstein, Nathalie Conte, Terrence F. Meehan
A figure showing the process of generating and using PDX models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e07c88d40f7248397f4cc8053bf7da
https://doi.org/10.1158/0008-5472.22419099
https://doi.org/10.1158/0008-5472.22419099
Autor:
Li Chen, Jacqueline Mudd, Michael Ittmann, Carol J. Bult, Amanda R. Kirane, Jelena Randjelovic, Stephen Scott, Yige Wu, Li Ding, Vashisht G. Yennu-Nanda, Jing Wang, Christopher D. Lanier, Maihi Fujita, Emilio Cortes-Sanchez, Sienna Rocha, Susan G. Hilsenbeck, Kian-Huat Lim, Fernanda Martins Rodrigues, Jill Rubinstein, Nicholas Mitsiades, Haiyin Lin, Jayamanna Wickramasinghe, Andrew Butterfield, Bryan E. Welm, Alana L. Welm, Jose P. Zevallos, Jason Held, Nicole B. Coggins, Song Cao, Yuanxin Xi, Brenda C. Timmons, Paul Lott, David Menter, Shunqiang Li, Tina Primeau, Fei Yang, Andrea Wang-Gillam, Ramaswamy Govindan, Dali Li, Brandi Davis-Dusenbery, Sara Seepo, Michael C. Wendl, Jeffrey Grover, Brian S. White, Clifford G. Tepper, Peter N. Robinson, Michael A. Davies, Zhengtao Chu, Michael W. Lloyd, Hua Sun, Xiaoshan Zhang, Tamara Stankovic, Dylan Fingerman, Anuj Srivastava, Luis G. Carvajal-Carmona, Don L. Gibbons, Lijun Yao, Rebecca Aft, Hongyong Zhang, Ismail Meraz, John DiGiovanna, Scott Kopetz, Ling Zhao, Guadalupe Polanco-Echeverry, Feng Chen, Jeremy Hoog, Matthew A. Wyczalkowski, George Xu, John D. Minna, Yi Xu, Julie Belmar, Xiaowei Xu, Luc Girard, Dennis A. Dean, Tijana Borovski, Chong-xian Pan, Cynthia X. Ma, Alexa Morales Arana, Yize Li, Turcin Saridogan, Steven B. Neuhauser, Sandra Scherer, Vicki Chin, Rose Tipton, David R. Gandara, Sherri R. Davies, Argun Akcakanat, Rajesh Patidar, Julie K. Schwarz, Soner Koc, Gao Boning, Michael Kim, Bryce P. Kirby, Yvonne A. Evrard, Hyunsil Park, Christian Frech, Chia-Kuei Mo, Ran Zhang, Brian A. Van Tine, Jonathan W. Reiss, Min Xiao, Xing Yi Woo, Tiffany Le, Ana Estrada, Xiaofeng Zheng, Jeffrey A. Moscow, Mourad Majidi, Nadezhda V. Terekhanova, Katherine Fuh, Erkan Yuca, Timothy A. Yap, Jianhua Zhang, Matthew J. Ellis, Shannon Westin, James H. Doroshow, Vito W. Rebecca, Moon S. Chen, Coya Tapia, Reyka G Jayasinghe, Jack A. Roth, Jithesh Augustine, Ryan C. Fields, Michae T. Tetzlaff, Michael T. Lewis, Kurt W. Evans, Ralph W. deVere White, Brian J. Sanderson, May Cho, Jeffrey H. Chuang, Tiffany Wallace, Ryan Jeon, Ted Toal, Matthew H. Bailey, Bert W. O'Malley, Katherine L. Nathanson, Qin Liu, Benjamin J. Raphael, Jingqin Luo, Salma Kaochar, Huiqin Chen, Rajasekharan Somasundaram, Daniel Cui Zhou, John F. DiPersio, Andrew V. Kossenkov, Bingliang Fang, Vanessa Jensen, Simone Zaccaria, Alexey Sorokin, Ai-Hong Ma, Sidharth V. Puram, Min Jin Ha, Meenhard Herlyn, R. Jay Mashl, Kelly Gale, Bingbing Dai, Lacey E. Dobrolecki, Chieh-Hsiang Yang, Funda Meric-Bernstam
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications
Nature Communications
Development of candidate cancer treatments is a resource-intensive process, with the research community continuing to investigate options beyond static genomic characterization. Toward this goal, we have established the genomic landscapes of 536 pati
Autor:
Brian S. White, Xing Yi Woo, Soner Koc, Todd Sheridan, Steven B. Neuhauser, Shidan Wang, Yvonne A. Evrard, John David Landua, R Jay Mashl, Sherri R. Davies, Bingliang Fang, Maria Gabriela Raso, Kurt W. Evans, Matthew H. Bailey, Yeqing Chen, Min Xiao, Jill Rubinstein, Ali Foroughi pour, Lacey Elizabeth Dobrolecki, Maihi Fujita, Junya Fujimoto, Guanghua Xiao, Ryan C. Fields, Jacqueline L. Mudd, Xiaowei Xu, Melinda G. Hollingshead, Shahanawaz Jiwani, PDXNet consortium, Tiffany A. Wallace, Jeffrey A. Moscow, James H. Doroshow, Nicholas Mitsiades, Salma Kaochar, Chong-xian Pan, Moon S. Chen, Luis G. Carvajal-Carmona, Alana L. Welm, Bryan E. Welm, Ramaswamy Govindan, Shunqiang Li, Michael A. Davies, Jack A. Roth, Funda Meric-Bernstam, Yang Xie, Meenhard Herlyn, Li Ding, Michael T. Lewis, Carol J. Bolt, Dennis A. Dean, Jeffrey H. Chuang
Publikováno v:
Cancer Research. 83:5407-5407
Patient-derived xenografts (PDXs) model human intra-tumoral heterogeneity in the context of the intact tissue of immunocompromised mice. Histological imaging via hematoxylin and eosin (H&E) staining is performed on PDX samples for routine assessment
Autor:
Dale A. Begley, Debra M. Krupke, Steven B. Neuhauser, Emily L. Jocoy, John P. Sundberg, Carol J. Bult
Publikováno v:
Cancer Research. 83:14-14
The laboratory mouse is the premier animal model system for in vivo studies of the genetic and genomic basis of cancer in humans. Although thousands of mouse models have been generated, finding relevant data and knowledge about these models is compli