Zobrazeno 1 - 10
of 1 296
pro vyhledávání: '"B, Lindner"'
Autor:
Antoine Levrier, Ioannis Karpathakis, Bruce Nash, Steven D. Bowden, Ariel B. Lindner, Vincent Noireaux
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Bacteriophages constitute an invaluable biological reservoir for biotechnology and medicine. The ability to exploit such vast resources is hampered by the lack of methods to rapidly engineer, assemble, package genomes, and select phages. Cel
Externí odkaz:
https://doaj.org/article/ca6a35bacd264b17bc6ee783365176cb
Autor:
Yifan Yang, Omer Karin, Avi Mayo, Xiaohu Song, Peipei Chen, Ana L. Santos, Ariel B. Lindner, Uri Alon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Genetically identical cells in the same stressful condition die at different times. The origin of this stochasticity is unclear; it may arise from different initial conditions that affect the time of demise, or from a stochastic damage accum
Externí odkaz:
https://doaj.org/article/f4c5c6eb09364973a87d9cc6c5c56541
Autor:
Nadine Bongaerts, Zainab Edoo, Ayan A. Abukar, Xiaohu Song, Sebastián Sosa-Carrillo, Sarah Haggenmueller, Juline Savigny, Sophie Gontier, Ariel B. Lindner, Edwin H. Wintermute
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Whole-cell screening for Mycobacterium tuberculosis inhibitors is complicated by the pathogen’s slow growth and biocontainment requirements. Here the authors develop engineered E. coli as a synthetic biology tool to express and screen metabolic tar
Externí odkaz:
https://doaj.org/article/954339c29a5245b5a82434151be0eb50
Publikováno v:
PLoS Biology, Vol 19, Iss 12, p e3001489 (2021)
A recent commentary raised concerns about aspects of the model and assumptions used in a previous study which demonstrated that selection can favor chromosomal alleles that confer higher plasmid donation rates. Here, the authors of that previous stud
Externí odkaz:
https://doaj.org/article/132a3b076e574accbec5513ae93451d8
Autor:
Arno Klein, Jon Clucas, Anirudh Krishnakumar, Satrajit S Ghosh, Wilhelm Van Auken, Benjamin Thonet, Ihor Sabram, Nino Acuna, Anisha Keshavan, Henry Rossiter, Yao Xiao, Sergey Semenuta, Alessandra Badioli, Kseniia Konishcheva, Sanu Ann Abraham, Lindsay M Alexander, Kathleen R Merikangas, Joel Swendsen, Ariel B Lindner, Michael P Milham
Publikováno v:
Journal of Medical Internet Research, Vol 23, Iss 11, p e22369 (2021)
BackgroundUniversal access to assessment and treatment of mental health and learning disorders remains a significant and unmet need. There are many people without access to care because of economic, geographic, and cultural barriers, as well as the l
Externí odkaz:
https://doaj.org/article/7e73b5116a394f5fb65375019560d61d
Autor:
Antoine L Decrulle, Antoine Frénoy, Thomas A Meiller-Legrand, Aude Bernheim, Chantal Lotton, Arnaud Gutierrez, Ariel B Lindner
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 10, p e1009475 (2021)
Evolution is often an obstacle to the engineering of stable biological systems due to the selection of mutations inactivating costly gene circuits. Gene overlaps induce important constraints on sequences and their evolution. We show that these constr
Externí odkaz:
https://doaj.org/article/f2bd32c24ae24d3ca118ea95cdf465b0
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245718 (2021)
Massive Open Online Course (MOOC) platforms incorporate large course catalogs from which individual students may register multiple courses. We performed a network-based analysis of student achievement, considering how course-course interactions may p
Externí odkaz:
https://doaj.org/article/9ed6f19ce126459e83f6f03831e95638
Autor:
Aïda Bafeta, Jason Bobe, Jon Clucas, Pattie Pramila Gonsalves, Célya Gruson-Daniel, Kathy L Hudson, Arno Klein, Anirudh Krishnakumar, Anna McCollister-Slipp, Ariel B Lindner, Dusan Misevic, John A Naslund, Camille Nebeker, Aki Nikolaidis, Irene Pasquetto, Gabriela Sanchez, Matthieu Schapira, Tohar Scheininger, Félix Schoeller, Anibal Sólon Heinsfeld, François Taddei
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 9, p e1007846 (2020)
Externí odkaz:
https://doaj.org/article/1499f0dbe40945719c672b7a3ebde618
Publikováno v:
PLoS Biology, Vol 18, Iss 8, p e3000814 (2020)
Plasmid-mediated horizontal gene transfer of antibiotic resistance and virulence in pathogenic bacteria underlies a major public health issue. Understanding how, in the absence of antibiotic-mediated selection, plasmid-bearing cells avoid being outnu
Externí odkaz:
https://doaj.org/article/8e122dac967340abbd58c9a7ccace49a
Autor:
Zoran S Marinkovic, Clément Vulin, Mislav Acman, Xiaohu Song, Jean-Marc Di Meglio, Ariel B Lindner, Pascal Hersen
Publikováno v:
eLife, Vol 8 (2019)
Microbial colonies are fascinating structures in which growth and internal organization reflect complex morphogenetic processes. Here, we generated a microfluidics device with arrays of long monolayer yeast colonies to further global understanding of
Externí odkaz:
https://doaj.org/article/0ea0d97f1b5b475ab8e94f58a02e27ba