Zobrazeno 1 - 10
of 213
pro vyhledávání: '"B, Lammek"'
Publikováno v:
Acta hydrochimica et hydrobiologica. 27:350-356
Fourteen polycyclic aromatic hydrocarbons (PAH), six monosaccharides (SA) formed following the hydrolysis of polysaccharides, as well as water and organic matter contents were determined in river sediments sampled in thirteen points in the Odra basin
Publikováno v:
Experientia. 47:83-86
Substitution of arginine for glutamine in the 4-position of a vasopressin V1 antagonist has been reported to turn it into an agonist. We resynthesized this 4-arginine analog and synthesized additional cyclic and linear vasopressin antagonists contain
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 63(4)
Two cyclic analogs of vasopressin, -Pro-Arg-Gly-NH(2) (1) and -Pro-Arg-Gly-NH(2) (2) were synthesized by the solid phase method. Their structure was determined in aqueous solution by two-dimensional NMR techniques and simulated annealing algorithm fr
Autor:
O, Dawidowska, A, Prahl, W, Kowalczyk, I, Derdowska, B, Lammek, T H, Wierzba, W, Juzwa, K, Neubert, J, Zabrocki, B, Olejniczak
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 63(1)
Two new analogues of a previously designed bradykinin (BK) antagonist, d-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-d-Phe-Thi-Arg, substituted in position 8 by N-benzylglycine and N-benzyl-l-alanine were designed, synthesized and bioassayed. The results show an imp
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 62(2)
In this study we describe the synthesis and some pharmacological properties of seven new analogues of arginine vasopressin (AVP) substituted in position 2 or 3 with 1-aminocyclohexane-1-carboxylic acid (Acc). All peptides were tested for the pressor,
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 57(2)
In this study we describe the synthesis and some pharmacological properties of four analogs of oxytocin. Three of these peptides contain the ethylene-bridged dipeptide D-Phe-D-Phe at positions 2 and 3; one had two N-Me-D-Phe residues. All analogs wer
Autor:
I, Derdowska, A, Prahl, K, Neubert, B, Hartrodt, A, Kania, D, Dobrowolski, S, Melhem, H I, Trzeciak, T, Wierzba, B, Lammek
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 57(1)
The present paper describes the synthesis and some pharmacological properties of two new bradykinin analogues containing the ethylene-bridged dipeptide Phe-Phe in their molecules. In a further two peptides this modification was combined with acylatio
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 56(6)
Introduction of the naphthylalanine residue into either position 3 of arginine vasopressin (AVP), or its analogs results in peptides with interesting pharmacological properties. The single substituted analog of AVP with L-2-Nal in position 3 causes m
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 53(5)
This study describes the synthesis and some pharmacological properties of three new analogs of arginine vasopressin (AVP) substituted in position 3 with (R)-alpha-hydroxymethylphenylalanine ([R]-HmPhe). All new peptides were tested for vasopressor an
Publikováno v:
Journal of computer-aided molecular design. 13(1)
Subject of this work is the analysis of molecular dynamics (MD) trajectories of neurophysins I (NPI) and II (NPII) and their complexes with the neurophyseal nonapeptide hormones oxytocin (OT) and vasopresssin (VP), respectively, simulated in water. N