Zobrazeno 1 - 10
of 209
pro vyhledávání: '"B, Jump"'
Autor:
Jyothi Padiadpu, Manuel Garcia‐Jaramillo, Nolan K Newman, Jacob W Pederson, Richard Rodrigues, Zhipeng Li, Sehajvir Singh, Philip Monnier, Giorgio Trinchieri, Kevin Brown, Amiran K Dzutsev, Natalia Shulzhenko, Donald B Jump, Andrey Morgun
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 11, Pp 1-21 (2023)
Abstract Clinical and preclinical studies established that supplementing diets with ω3 polyunsaturated fatty acids (PUFA) can reduce hepatic dysfunction in nonalcoholic steatohepatitis (NASH) but molecular underpinnings of this action were elusive.
Externí odkaz:
https://doaj.org/article/d61e92523d9e4acf87080e7f0b5b8143
Autor:
Jyothi Padiadpu, Melinda H. Spooner, Zhipeng Li, Nolan Newman, Christiane V. Löhr, K. Denise Apperson, Amiran Dzutsev, Giorgio Trinchieri, Natalia Shulzhenko, Andrey Morgun, Donald B. Jump
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
BackgroundNonalcoholic fatty liver disease (NAFLD) is a global health problem. Identifying early gene indicators contributing to the onset and progression of NAFLD has the potential to develop novel targets for early therapeutic intervention. We repo
Externí odkaz:
https://doaj.org/article/46edeae843a44a259ad0dbc2f51e195b
Autor:
Melinda H Spooner, Manuel Garcia-Jaramillo, K Denise Apperson, Christiane V Löhr, Donald B Jump
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292432 (2023)
BackgroundNonalcoholic fatty liver disease (NAFLD) is a global health problem. Identification of factors contributing to the onset and progression of NAFLD have the potential to direct novel strategies to combat NAFLD.MethodsWe examined the time cour
Externí odkaz:
https://doaj.org/article/53a9654b84ec44cebf38a448fccc953d
Autor:
Richard R. Rodrigues, Manoj Gurung, Zhipeng Li, Manuel García-Jaramillo, Renee Greer, Christopher Gaulke, Franziska Bauchinger, Hyekyoung You, Jacob W. Pederson, Stephany Vasquez-Perez, Kimberly D. White, Briana Frink, Benjamin Philmus, Donald B. Jump, Giorgio Trinchieri, David Berry, Thomas J. Sharpton, Amiran Dzutsev, Andrey Morgun, Natalia Shulzhenko
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Abstract Western diet (WD) is one of the major culprits of metabolic disease including type 2 diabetes (T2D) with gut microbiota playing an important role in modulating effects of the diet. Herein, we use a data-driven approach (Transkingdom Network
Externí odkaz:
https://doaj.org/article/2d75b1d838834d4e88d47f7baca85691
Autor:
Stephen A Martin, Kenneth A Philbrick, Carmen P Wong, Dawn A Olson, Adam J Branscum, Donald B Jump, Charles K Marik, Jonathan M DenHerder, Jennifer L Sargent, Russell T Turner, Urszula T Iwaniec
Publikováno v:
Endocrine Connections, Vol 8, Iss 11, Pp 1455-1467 (2019)
Mice are a commonly used model to investigate aging-related bone loss but, in contrast to humans, mice exhibit cancellous bone loss prior to skeletal maturity. The mechanisms mediating premature bone loss are not well established. However, our previo
Externí odkaz:
https://doaj.org/article/907570d8c66745c4babfe90e48a0b1f0
Autor:
Yang Zhang, Gerd Bobe, Cristobal L Miranda, Malcolm B Lowry, Victor L Hsu, Christiane V Lohr, Carmen P Wong, Donald B Jump, Matthew M Robinson, Thomas J Sharpton, Claudia S Maier, Jan F Stevens, Adrian F Gombart
Publikováno v:
eLife, Vol 10 (2021)
We previously reported xanthohumol (XN), and its synthetic derivative tetrahydro-XN (TXN), attenuates high-fat diet (HFD)-induced obesity and metabolic syndrome in C57Bl/6J mice. The objective of the current study was to determine the effect of XN an
Externí odkaz:
https://doaj.org/article/2429acd383fb4e10be829a3c44468c2f
Autor:
D. Elizabeth Le, Manuel García-Jaramillo, Gerd Bobe, Armando Alcazar Magana, Ashish Vaswani, Jessica Minnier, Donald B. Jump, Diana Rinkevich, Nabil J. Alkayed, Claudia S. Maier, Sanjiv Kaul
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: While oxylipins have been linked to coronary artery disease (CAD), little is known about their diagnostic and prognostic potential.Objective: We tested whether plasma concentration of specific oxylipins may discriminate among number of di
Externí odkaz:
https://doaj.org/article/a2a4a033b1694a12b6d47c65600741e9
Autor:
Manoj Gurung, Zhipeng Li, Hannah You, Richard Rodrigues, Donald B Jump, Andrey Morgun, Natalia Shulzhenko
Publikováno v:
EBioMedicine, Vol 51, Iss , Pp - (2020)
A substantial body of literature has provided evidence for the role of gut microbiota in metabolic diseases including type 2 diabetes. However, reports vary regarding the association of particular taxonomic groups with disease. In this systematic rev
Externí odkaz:
https://doaj.org/article/8d904ed4cd154c21816da6edc9095e9f
Autor:
Manuel Garcia-Jaramillo, Melinda H Spooner, Christiane V Löhr, Carmen P Wong, Weijian Zhang, Donald B Jump
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214387 (2019)
BackgroundNonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, particularly in obese and type 2 diabetic individuals. NAFLD ranges in severity from benign steatosis to nonalcoholic steatohepatitis (NASH); and N
Externí odkaz:
https://doaj.org/article/e441729982ab453c99a9a68bd9549d92
Autor:
Melinda H. Spooner, Donald B. Jump
Publikováno v:
Annual Review of Nutrition. 43
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic fatty liver disease worldwide, particularly in obese and type 2 diabetic individuals. Currently, there are no therapies for NAFLD that have been approved by the US Food and Drug Admi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48cb51732415e89c3bd46c33da659043
https://doi.org/10.1146/annurev-nutr-061021-030223
https://doi.org/10.1146/annurev-nutr-061021-030223